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NASDAQ · Biotechnology · USD

Tyra Biosciences, Inc. (TYRA) Stock Analysis

Tyra Biosciences, Inc. (TYRA) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

TYRA

$28.65

+$3.79 (+15.25%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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TYRA Key Statistics

As of Sep 4, 2026
Trading
Open
$24.51
Previous Close
$24.86
Day's Range
24.51–29.56
52-Week Range
11.70–40.65
Volume
1.86M
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
0.73
Valuation
Market Cap
$1.71B
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−2.39
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$119.95M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
59.68M
1-Year Return
+136.00%
Dividend and dates
Earnings Date
November 4, 2026estimated
Avg Volume
734.20K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

TYRA Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+8.98%
2025+89.14%
2024+0.36%
2023+82.24%
2022−45.98%
2021 (partial year)−45.88%

As of September 4, 2026.

TYRA Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$119.95M—
2024$0.00−$86.48M—
2023$0.00−$69.13M—
2022$0.00−$55.33M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$132.76M−$119.95M—
2024$0.00—−$104.18M−$86.48M—
2023$0.00—−$79.95M−$69.13M—
2022$0.00—−$58.93M−$55.33M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

TYRA Valuation vs Biotechnology Median

Median of 656 stocks
MetricTYRABiotechnology medianvs median
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Tyra Biosciences, Inc. (TYRA) is capitalised at $1.71B on the latest close. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 87.

The most recent close on file for TYRA is $28.65, dated September 4, 2026. That is +$3.79 (+15.25%) against the previous close. The 52-week range on file runs from $11.70 to $40.65. The latest close sits 144.81% above that 52-week low.

Financial Health

In fiscal 2025, Tyra Biosciences, Inc. reported revenue of $0.00. The same year closed with a net loss of $119.95M. Profit margin runs at 0%. Trailing earnings per share are −2.39.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Over the trailing twelve months the price has returned +136.00%. Across 5 years the annualized return works out at +1.96%. Beta against the wider market is reported at 0.73. Daily returns over the trailing 5 years annualize to a volatility of 81.14%.

Growth & Income

The record shows no dividend for TYRA.

2026 is still running; the price is +8.98% year to date. The strongest complete calendar year on file is 2025 at +89.14%; the weakest is 2022 at −45.98%. Of the 4 complete calendar years on file, 3 finished higher.

Peer Comparison

Tyra Biosciences, Inc. (TYRA) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Tyra Biosciences, Inc. TYRA $1.71B —
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Tyra Biosciences, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Tyra Biosciences, Inc.

Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is FGFR3, which is in clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in clinical trial for intrahepatic cholangiocarcinoma; and TYRA-430 for the treatment of hepatocellular carcinoma. Tyra Biosciences, Inc. was incorporated in 2018 and is headquartered in Carlsbad, California.

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