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BeOne Medicines AG (ONC) Stock Analysis

Healthcare

BeOne Medicines AG

$302.44

$-7.81 (-2.52%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

BeOne Medicines AG is an oncology-focused entity dedicated to the discovery and development of novel treatments for cancer patients across the United States, China, Europe, and international markets. Operating within the healthcare sector and specifically the biotechnology industry, the company leverages biological and chemical sciences to advance therapies that target specific disease mechanisms. The firm currently maintains a substantial market capitalization of $32.47B, supported by annual revenue of $5.34B and an organizational scale comprising approximately 12,000 employees. These valuation and revenue figures indicate that the company holds a significant position within the global biotechnology landscape, reflecting a high level of market confidence and substantial operational footprint relative to peers in the specialized oncology space.

Financial Health

The company reported revenue of $5.34B over the trailing twelve months, generating a net income of $286.93M and an EBITDA of $578.82M during the same period. The substantial gap between the $5.34B revenue and the $286.93M net income reveals a cost structure where operating expenses, such as research and development and commercialization costs, absorb a significant portion of top-line growth before reaching the bottom line. Free cash flow stands at $727.12M, which provides the company with considerable financial flexibility to fund ongoing clinical trials, expand its commercial infrastructure, or return capital to stakeholders without relying on external financing. Profitability is characterized by a gross margin of 87.5%, an operating margin of 12.4%, and a profit margin of 5.4%, indicating high efficiency in production relative to sales but moderate operating leverage and net profitability typical of capital-intensive biotech firms. The balance sheet displays a cash position of $4.55B against total debt of $1.09B, while the debt-to-equity ratio is recorded at 25.06, suggesting a capital structure that relies heavily on equity financing rather than leverage. Liquidity is robust, evidenced by a current ratio of 3.41, which signifies that the company possesses more than three times the liquid assets required to cover its short-term liabilities. Return on equity is 7.5% and return on assets is 4.0%, metrics that reveal management's effectiveness in generating returns on shareholder capital and utilizing the company's asset base to produce earnings.

Valuation Assessment

Valuation multiples show a trailing P/E ratio of 114.93 and a forward P/E of 30.41, where the significant difference implies that the market expects a dramatic expansion in earnings per share over the coming years to justify the current high multiple. The price-to-book ratio is 7.19, indicating that the market values the company at more than seven times its net asset book value, reflecting a premium assigned to its intangible assets and future drug pipeline potential. Alternative valuation metrics include a price-to-sales ratio of 6.08 and an EV/EBITDA of 698.49, which suggest that investors are pricing the stock based on future revenue generation and cash flow potential rather than current profitability or asset backing. The stock has traded within a 52-week range with a high of $385.22 and a low of $196.45, placing the current price contextually within this historical volatility band. The beta value is 0.52, which indicates that the stock's price volatility is less than half that of the broader market, suggesting a defensive characteristic often found in large-cap biotechnology firms despite the inherent risks of the sector.

Growth & Income

Revenue growth year-over-year is recorded at 32.8%, while earnings growth year-over-year is listed as N/A, implying that current earnings figures do not yet reflect the rapid expansion of the top line seen in the revenue stream. Since earnings growth data is not available in the provided facts, the analysis focuses on the revenue trajectory, which suggests the company is scaling its commercial operations faster than its reported profitability is currently capturing. The company does not pay a dividend, with a dividend yield of N/A and a payout ratio of 0.0%, meaning that all generated earnings are retained within the organization to fuel research, development, and market expansion initiatives. This reinvestment strategy aligns with the typical lifecycle of a biotechnology company prioritizing pipeline growth over immediate income distribution to shareholders.

Peer Comparison

BeOne Medicines AG (ONC) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
BeOne Medicines AG ONC $32.19B 70.3
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. BeOne Medicines AG trades at a P/E of 70.3.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About BeOne Medicines AG

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.

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Key Statistics

Market Cap
$32.19B
P/E Ratio
70.35
52-Week High
$385.22
52-Week Low
$235.35
Avg Volume
242.78K
Beta
0.50

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
Switzerland
Employees
12,000