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Apellis Pharmaceuticals, Inc. (APLS) 株式分析

ヘルスケア

Apellis Pharmaceuticals, Inc.

$41.03

+$0.00 (+0.00%)

最終更新日: 2026年5月15日

株価推移

分析

企業概要

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical enterprise dedicated to the discovery, development, and commercialization of novel therapeutic compounds designed to address diseases with significant unmet medical needs. The company operates within the broader Healthcare sector, specifically functioning in the Biotechnology industry, a classification that signifies its focus on innovation-driven research and development rather than established consumer goods or services. In terms of scale, the entity holds a market capitalization of $5.20B, generated annual revenue of $1.00B, and maintains an employee count of 733 individuals. These valuation figures indicate that the market assigns a substantial premium to the company's intellectual property and pipeline potential, positioning it as a mid-to-large-cap player despite the inherent risks associated with the biotechnology industry's reliance on future clinical success and regulatory approvals.

財務健全性

The company reported a revenue of $1.00B over the trailing twelve months, with a corresponding net income of $22.39M and an EBITDA of $56.98M. The distinct gap between the $1.00B revenue figure and the $22.39M net income reveals a challenging cost structure where significant operating expenses, likely driven by research and development or sales overhead, consume a large portion of top-line growth before reaching the bottom line. The free cash flow stands at $-15,464,500, indicating a period where capital expenditures and operational burn exceed operating cash generation, which limits immediate financial flexibility for large-scale acquisitions or aggressive share buybacks without additional external financing. Margin analysis shows a gross margin of 60.3%, suggesting efficient manufacturing and supply chain management relative to the cost of goods sold, yet this is offset by an operating margin of -25.6% and a profit margin of 2.2%, highlighting the struggle to cover overhead costs and generate substantial operating profitability. On the balance sheet, the company holds $467.79M in cash against $474.36M in debt, resulting in a debt-to-equity ratio of 128.15, which characterizes the capital structure as highly leveraged given that debt significantly exceeds liquid cash reserves. Despite the leverage, the current ratio of 3.14 suggests a robust position in managing short-term liabilities with available assets, providing a buffer against immediate liquidity crises. Furthermore, the return on equity of 7.5% and return on assets of 3.5% indicate that while the company is profitable on a net basis, the high leverage and asset base dilute the efficiency of management in generating returns relative to the capital employed.

バリュエーション評価

The trailing twelve-month P/E ratio is 225.83, while the forward P/E is negative at -166.43, a disparity that implies the market expects earnings to be negative or volatile in the near future, preventing a meaningful price-to-earnings comparison for upcoming periods. The price-to-book ratio of 13.91 indicates that the stock trades at a substantial premium relative to its book value, reflecting investor confidence in the intangible value of the pharmaceutical pipeline and future revenue streams. Alternative valuation metrics such as the price-to-sales ratio of 5.18 and an EV/EBITDA of 91.30 suggest that investors are pricing the company based on sales growth potential and enterprise value rather than current profitability, which is typical for biotechnology firms in the commercial stage. Regarding trading range, the 52-week high is $40.76 and the low is $16.10, meaning the current price sits somewhere within this historical volatility band, subject to market sentiment regarding clinical data and regulatory milestones. The beta value of -0.20 is anomalous for a large-cap stock and indicates an inverse correlation to the broader market, suggesting that the stock price moves in the opposite direction of the general market index, which could be attributed to specific idiosyncratic factors or data errors in the reporting metrics provided.

Growth & Income

The revenue growth year-over-year is -5.9%, while earnings growth is listed as N/A, indicating that the company is currently contracting its sales base rather than expanding it, which contradicts typical growth expectations for a commercial-stage biopharmaceutical firm. Since the earnings growth is not available and the company does not pay a dividend, there is no payout ratio or dividend yield to analyze for sustainability. Consequently, the company reinvests its limited earnings and cash reserves into ongoing research, development, and commercialization efforts rather than distributing capital to shareholders, a strategy necessary to sustain the pipeline but which foregoes immediate income generation for investors. The overall growth and income profile is characterized by a contraction in revenue and a lack of dividend distribution, highlighting a focus on long-term product lifecycle extension and new indications rather than short-term financial returns or income stability for the shareholder base.

同業他社比較

Apellis Pharmaceuticals, Inc. (APLS) はバイオテクノロジー業界で事業を展開しています。時価総額による最も近い同業他社との比較は以下の通りです:

企業名 ティッカー 時価総額 PER
Apellis Pharmaceuticals, Inc. APLS $5.25B 38.4
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

バイオテクノロジー業界の平均PERは53.8倍です。Apellis Pharmaceuticals, Inc.のPERは38.4です。

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Apellis Pharmaceuticals, Inc.について

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, focal segmental glomerulosclerosis, and delayed graft function; and APL-3007, a small interfering RNA, or siRNA for the treatment of GA. In addition, it conducts preclinical studies for APL-9099, a treatment targeting the neonatal Fc receptor, or FcRn, which has the potential to be a first-in-class gene editing treatment for future target indications with one-time dosing; and developing other programs with its proprietary in-house capabilities and under its Beam collaboration. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics, Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is headquartered in Waltham, Massachusetts. As of May 14, 2026, Apellis Pharmaceuticals, Inc. operates as a subsidiary of Biogen Inc.

企業説明は英語で表示されています。

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主要指標

時価総額
$5.25B
PER
38.35
52週高値
$41.14
52週安値
$16.61
平均出来高
6.37M
ベータ
-0.25

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企業情報

取引所
NASDAQ
United States
従業員数
733