NVDA+0.84%AAPL−2.51%GOOGL−1.17%MSFT−2.04%AMZN−0.15%TSM+2.85%SPCX−1.20%AVGO+0.21%
StockVS

NASDAQ · Biotechnology · USD

Phio Pharmaceuticals Corp. (PHIO) Stock Analysis

Phio Pharmaceuticals Corp. (PHIO) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

PHIO

$1.08

−$0.03 (−2.70%)

Sep 4, 2026 · Market close

Compare

Price History

Hover for the daily close. The dotted line marks the period open.

Compare PHIO with… →

PHIO Key Statistics

As of Sep 4, 2026
Trading
Open
$1.10
Previous Close
$1.11
Day's Range
1.08–1.13
52-Week Range
0.81–4.19
Volume
86.60K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
0.80
Valuation
Market Cap
$12.55M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−1.26
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$8.70M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
11.62M
1-Year Return
−47.57%
Dividend and dates
Avg Volume
630.90K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

PHIO Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+2.86%
2025−41.67%
2024−73.68%
2023−82.97%
2022−62.80%
2021−62.83%
2020−71.40%
2019−48.18%
2018−94.06%
2017−22.24%
2016 (partial year)−70.58%

As of September 4, 2026.

PHIO Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$8.70M—
2024$0.00−$7.15M—
2023$0.00−$10.83M—
2022$0.00−$11.48M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$9.22M−$8.70M—
2024$0.00—−$7.39M−$7.15M—
2023$0.00—−$10.70M−$10.83M—
2022$0.00—−$11.46M−$11.48M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

PHIO Valuation vs Biotechnology Median

Median of 656 stocks
MetricPHIOBiotechnology medianvs median
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Phio Pharmaceuticals Corp. (PHIO) carries a market capitalisation of $12.55M. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 6.

PHIO last closed at $1.08 on September 4, 2026. That is −$0.03 (−2.70%) against the previous close. Over the past 52 weeks the price has ranged from $0.81 to $4.19. The latest close sits 32.84% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $8.70M. Profit margin runs at 0%. Earnings per share on a trailing basis come to −1.26.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

The reported beta is 0.8. Annualized volatility over the trailing 10 years is 150.17%. The trailing one-year price return is −47.57%. Measured over 10 years, that is −68.96% a year compounded.

Growth & Income

The record shows no dividend for PHIO.

So far in 2026 the price is +2.86%. The strongest complete calendar year on file is 2017 at −22.24%; the weakest is 2018 at −94.06%. Of the 9 complete calendar years on file, 0 finished higher.

Peer Comparison

Phio Pharmaceuticals Corp. (PHIO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Phio Pharmaceuticals Corp. PHIO $12.55M —
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Phio Pharmaceuticals Corp. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

Related Biotechnology Stocks

VRTX

Vertex Pharmaceuticals Incorporated

$138.42B

 REGN

Regeneron Pharmaceuticals, Inc.

$85.22B

 ARGX

argenx SE

$64.25B

 MRNA

Moderna, Inc.

$58.11B

 RVMD

Revolution Medicines, Inc.

$45.01B

 ONC

BeOne Medicines AG

$40.53B
View all Biotechnology stocks →

Popular Healthcare Stocks

LLY

Eli Lilly and Company

$1.02T

 JNJ

Johnson & Johnson

$663.28B

 ABBV

AbbVie Inc.

$453.19B

 MRK

Merck & Co., Inc.

$370.89B

 UNH

UnitedHealth Group Incorporated

$356.47B
View all Healthcare stocks →

About Phio Pharmaceuticals Corp.

Phio Pharmaceuticals Corp., a clinical stage biopharmaceutical company, engages in the development of immuno-oncology therapeutics in the United States. It develops PH-762, an INTASYL compound designed to reduce the expression of PD-1 in multi-center Phase 1b dose-escalating clinical trials; PH-894, an INTASYL compound that is designed to specifically silence BRD4, a protein that controls gene expression in both T cells and tumor cells in preclinical studies. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. Phio Pharmaceuticals Corp. was founded in 2003 and is based in King Of Prussia, Pennsylvania.

Visit website →