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NASDAQ · Biotechnology · USD

Mereo BioPharma Group plc (MREO) Stock Analysis

Mereo BioPharma Group plc (MREO) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

MREO

$0.29

−$0.00 (−1.32%)

Oct 21, 2026 · Market close

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Price History

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MREO Key Statistics

As of Oct 21, 2026
Trading
Open
$0.30
Previous Close
$0.30
Day's Range
0.29–0.31
52-Week Range
0.20–2.37
Volume
329.28K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
0.14
Valuation
Market Cap
$46.50M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.20
Financials (FY)
Revenue (FY)
$500.00K
Net Income (FY)
−$41.88M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
159.69M
1-Year Return
−86.33%
Dividend and dates
Earnings Date
November 9, 2026estimated
Avg Volume
4.05M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, MREO closed at $0.29, −86.33% over 1 year.

Mereo BioPharma Group plc (MREO) has a market capitalization of $46.50M.

In fiscal 2025, MREO reported revenue of $500.00K.

MREO Stock Return by Calendar Year

Mereo BioPharma Group plc (MREO) return since Apr 2019: what $10,000 became

1 year
$10,000 $1,367
−86.33%
5 years
$10,000 $1,342
−86.58%
Since Apr 2019
$10,000 $448
−95.52%

If you had invested $10,000 in Mereo BioPharma Group plc (MREO) at the close on April 24, 2019, the earliest close on record here, it would have been worth $448 at the close on October 21, 2026: −95.52% in total, −33.93% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−30.17%
2025−88.09%
2024+51.52%
2023+208.00%
2022−53.13%
2021−55.31%
2020+9.15%
2019 (partial year)−49.54%

As of October 21, 2026.

MREO Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$500.00K−$41.88M−8,375.6%
2024$0.00−$43.25M—
2023$10.00M−$29.47M−294.7%
2022$0.00−$42.22M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$500.00K$367.00K−$38.26M−$41.88M−8,375.6%
2024$0.00$0.00−$45.72M−$43.25M—
2023$10.00M$7.43M−$27.14M−$29.47M−294.7%
2022$0.00$1.15M−$52.70M−$42.22M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Mereo BioPharma Group plc (MREO) is capitalised at $46.50M on the latest close. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 39 employees.

Over the past 52 weeks the price has ranged from $0.20 to $2.37. MREO last closed at $0.29 on October 21, 2026. That is $0.00 (−1.32%) against the previous close. The latest close sits 45.6% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $500.00K. The same year closed with a net loss of $41.88M. Earnings per share on a trailing basis come to −0.2.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $500.00K in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative.

Beta against the wider market is reported at 0.14. Annualized volatility over the trailing 7 years is 113.28%. Over the trailing twelve months the total return is −86.33%. Across 5 years the annualized return works out at −33.08%.

Growth & Income

The record shows no dividend for MREO.

The strongest complete calendar year on file is 2023 at +208.00%; the weakest is 2025 at −88.09%. Of the 6 complete calendar years on file, 3 finished higher. 2026 is still running; the total return is −30.17% year to date.

Peer Comparison

Mereo BioPharma Group plc (MREO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Mereo BioPharma Group plc MREO $46.50M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Mereo BioPharma Group plc has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Mereo BioPharma Group plc

Mereo BioPharma Group plc, a biopharmaceutical company, develops and commercializes therapeutics for the treatment of rare diseases in the United Kingdom and the United States. The company develops Setrusumab, an antibody for the treatment of osteogenesis imperfecta; Alvelestat, an oral small molecule that is in Phase II clinical trial to treat Alpha-1 anti-trypsin deficiency associated lung disease; and Vantictumab, an anti-FZD monoclonal antibody for the treatment of autosomal dominant osteopetrosis type 2. It also develops Leflutrozole, an oral aromatase inhibitor, which is in Phase 2 trials for use in the treatment of hypogonadotropic hypogonadism; Navicixizumab, which has completed Phase 1b clinical trials for the treatment of the late line ovarian cancer; Etigilimab, an IgG1 monoclonal antibody which binds to the human TIGIT receptor on immune cells for the Treatment of advanced solid tumors; and Acumapimod, a p38 MAP kinase inhibitor that is in Phase II clinical trials to treat acute exacerbations of chronic obstructive pulmonary disease. The company has a license agreement with Feng Biosciences for the development and commercialization of navicixizumab; license agreement with ReproNovo for the development and commercialization of leflutrozole; and licensing agreement with AstraZeneca. Mereo BioPharma Group plc was incorporated in 2015 and is headquartered in London, United Kingdom.

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