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NASDAQ · Biotechnology · USD

Ligand Pharmaceuticals Incorporated (LGND) Stock Analysis

Ligand Pharmaceuticals Incorporated (LGND) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

LGND

$314.78

+$8.38 (+2.73%)

Oct 21, 2026 · Market close

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Price History

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LGND Key Statistics

As of Oct 21, 2026
Trading
Open
$305.36
Previous Close
$306.40
Day's Range
303.93–317.64
52-Week Range
175.89–326.63
Volume
222.60K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.01
Valuation
Market Cap
$6.28B
P/E Ratio
33.17
Forward P/EShare price divided by forecast earnings for the year ahead, rather than the year just past.
26.32
PEG RatioThe P/E ratio divided by the expected earnings growth rate. It puts a high P/E in the context of how fast profits are growing.
1.53
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
21.60
EPS (ttm)Profit attributable to each share over the last twelve months.
9.49
Financials (FY)
Revenue (FY)
$268.09M+60.40%
Net Income (FY)
$124.45M
Profit marginThe share of revenue left as profit after all costs and taxes.
67.88%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
19.94M
1-Year Return
+68.64%
Dividend and dates
Earnings Date
October 29, 2026
Avg Volume
245.55K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, LGND closed at $314.78, +68.64% over 1 year.

Ligand Pharmaceuticals Incorporated (LGND) has a market capitalization of $6.28B.

In fiscal 2025, LGND reported revenue of $268.09M.

LGND Stock Return by Calendar Year

Ligand Pharmaceuticals Incorporated (LGND) 10-year return: what $10,000 became

1 year
$10,000 $16,864
+68.64%
5 years
$10,000 $38,120
+281.20%
10 years
$10,000 $53,961
+439.61%

If you had invested $10,000 in Ligand Pharmaceuticals Incorporated (LGND) 10 years ago, at the close on October 21, 2016, it would have been worth $53,961 at the close on October 21, 2026: +439.61% in total, +18.36% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+66.49%
2025+76.45%
2024+50.03%
2023+6.92%
2022−30.67%
2021+55.31%
2020−4.64%
2019−23.15%
2018−0.90%
2017+34.76%
2016 (partial year)−13.49%

As of October 21, 2026.

LGND Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$268.09M$124.45M46.4%
2024$167.13M−$4.03M−2.4%
2023$131.31M$52.15M39.7%
2022$196.25M−$33.36M−17.0%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$268.09M$253.54M$47.20M$124.45M46.4%
2024$167.13M$156.06M$23.02M−$4.03M−2.4%
2023$131.31M$120.80M$9.82M$52.15M39.7%
2022$196.25M$143.42M$3.04M−$33.36M−17.0%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

LGND Valuation vs Biotechnology Median

Median of 608 stocks
MetricLGNDBiotechnology medianvs median
P/E33.1716.60100% above
P/S ratio21.6013.3062% above
Profit margin67.88%−38.31%106.2 pts above

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 20 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Ligand Pharmaceuticals Incorporated (LGND) at $6.28B. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 47.

The 52-week range on file runs from $175.89 to $326.63. LGND last closed at $314.78 on October 21, 2026. That is +$8.38 (+2.73%) against the previous close. The latest close sits 78.96% above that 52-week low.

Financial Health

The most recent full year on file, fiscal 2025, shows revenue of $268.09M. That is +60.40% against the prior fiscal year, when revenue was $167.13M. Net income for the same year was $124.45M. Profit margin runs at 67.88%. That is 106.2 percentage points above the Biotechnology median of −38.31%. Earnings per share on a trailing basis come to 9.49.

Across the 4 fiscal years on file, revenue moves from $196.25M in 2022 to $268.09M in 2025. Of those 4 years, 2 report positive net income.

Valuation Assessment

The trailing P/E ratio stands at 33.17. That is 99.82% above the Biotechnology median of 16.6. The forward P/E on file is 26.32. The PEG ratio, which sets the P/E against expected earnings growth, reads 1.53. The price-to-sales ratio is 21.6. On price-to-sales that is 62.41% above the Biotechnology median of 13.3. 608 Biotechnology companies report these metrics, and the medians quoted come from that group.

The trailing one-year total return is +68.64%. Measured over 10 years, that is +18.36% a year compounded. The reported beta is 1.01. Annualized volatility over the trailing 10 years is 45.66%.

Growth & Income

The record shows no dividend for LGND.

Across the complete calendar years on file, 2025 returned +76.45% and 2022 returned −30.67%. Of the 9 complete calendar years on file, 5 finished higher. 2026 is still running; the total return is +66.49% year to date.

Peer Comparison

Ligand Pharmaceuticals Incorporated (LGND) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Ligand Pharmaceuticals Incorporated LGND $6.28B 33.2
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Ligand Pharmaceuticals Incorporated trades at a P/E of 33.2.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Ligand Pharmaceuticals Incorporated

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL, MenFive, and ZELSUVMI for infectious disease; EVOMELA and KYPROLIS for multiple myeloma; FILSPARI for the treatment of immunoglobulin a nephropathy; PNEUMOSIL, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia in children; and QARZIBA to treat neuroblastoma. The company also provides Teriparatide injection product for osteoporosis; RYLAZE, a recombinant erwinia asparaginase for acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes in adults and children aged 8 years and older with Stage 2 T1D; and VAXNEUVANCE for the prevention of invasive disease caused by streptococcus pneumoniae serotypes. In addition, it offers Duavee for menopause; Frovatriptan to treat Neurology; FYCOMPA and SESQUIENT for CNS; MEKINIST for cardiology; Nexterone, a captisol-enabled formulation of amiodarone; VEKLURY, an antiviral treatment for COVID-19; and Viviant for osteoporosis. Further, the company develops ACLX-002, Ciforadenant, UGN-301, Viright, MB07133, BOT/BAL, and Lasofoxifene for oncology; Ensifentrine for respiratory disease; QTORIN for rare disease; Sparsentan for kidney disease; VK2809 for hepatology; ANEB-001 for acute cannabinoid intoxication; Reproxalap for opthamology; VK0214 for Rare Disease; and VK5211 for musculoskeletal disorder. The company was incorporated in 1987 and is based in Jupiter, Florida.

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