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NYSE American · Biotechnology · USD

Calidi Biotherapeutics, Inc. (CLDI) Stock Analysis

Calidi Biotherapeutics, Inc. (CLDI) is a Biotechnology stock listed on NYSE American and quoted in US Dollar.

CLDI

$1.39

+$0.03 (+2.59%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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CLDI Key Statistics

As of Sep 4, 2026
Trading
Open
$1.38
Previous Close
$1.35
Day's Range
1.35–1.40
52-Week Range
1.25–27.84
Volume
19.00K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.32
Valuation
Market Cap
$3.58M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−38.00
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$19.91M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
2.58M
1-Year Return
−94.49%
Dividend and dates
Avg Volume
293.93K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

CLDI Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−92.60%
2025−91.52%
2024−92.38%
2023−85.15%
2022+3.67%
2021 (partial year)+0.31%

As of September 4, 2026.

CLDI Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$19.91M—
2024$0.00−$22.14M—
2023$0.00−$29.22M—
2022$45.00K−$25.43M−56504.4%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$20.19M−$19.91M—
2024$0.00—−$21.60M−$22.14M—
2023$0.00$0.00−$26.11M−$29.22M—
2022$45.00K$31.00K−$23.13M−$25.43M−56504.4%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

CLDI Valuation vs Biotechnology Median

Median of 656 stocks
MetricCLDIBiotechnology medianvs median
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Calidi Biotherapeutics, Inc. (CLDI) carries a market capitalisation of $3.58M. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 29 employees.

CLDI last closed at $1.39 on September 4, 2026. That is +$0.03 (+2.59%) against the previous close. The 52-week range on file runs from $1.25 to $27.84. The latest close sits 10.8% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $19.91M. The reported profit margin is 0%. Trailing earnings per share are −38.

Across the 4 fiscal years on file, revenue moves from $45.00K in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative.

Beta against the wider market is reported at 1.32. Annualized volatility over the trailing 4 years is 147.66%. The trailing one-year price return is −94.49%. Across 3 years the annualized return works out at −95.71%.

Growth & Income

No dividend is on file for CLDI.

2026 is still running; the price is −92.60% year to date. The strongest complete calendar year on file is 2022 at +3.67%; the weakest is 2024 at −92.38%. Of the 4 complete calendar years on file, 1 finished higher.

Peer Comparison

Calidi Biotherapeutics, Inc. (CLDI) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Calidi Biotherapeutics, Inc. CLDI $3.58M —
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Calidi Biotherapeutics, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Calidi Biotherapeutics, Inc.

Calidi Biotherapeutics, Inc., a biotechnology company, develops targeted therapies to deliver genetic medicines to distal sites of disease. The company offers CLD-101, which is in Phase 1b/2 clinical trial for the treatment of newly diagnosed high grade glioma, as well as in Phase 1 dose-escalation clinical trial for recurrent high-grade glioma; CLD-201 product for solid tumors, such as breast cancer, head and neck cancer, and sarcoma; and CLD-401 for the treatment of metastatic solid tumors. It also offers oncolytic virus platforms, such as NeuroNova and SuperNova. Calidi Biotherapeutics, Inc. was founded in 2014 and is headquartered in San Diego, California.

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