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NASDAQ · Biotechnology · USD

Avalo Therapeutics, Inc. (AVTX) Stock Analysis

Avalo Therapeutics, Inc. (AVTX) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

AVTX

$19.23

+$0.23 (+1.21%)

Sep 4, 2026 · Market close

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Price History

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AVTX Key Statistics

As of Sep 4, 2026
Trading
Open
$18.81
Previous Close
$19.00
Day's Range
18.79–19.62
52-Week Range
9.54–24.27
Volume
633.20K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
0.79
Valuation
Market Cap
$1.03B
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−4.46
Financials (FY)
Revenue (FY)
$59.00K−86.62%
Net Income (FY)
−$78.26M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
53.63M
1-Year Return
+89.27%
Dividend and dates
Earnings Date
November 12, 2026estimated
Avg Volume
1.24M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

AVTX Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+5.89%
2025+144.41%
2024−18.35%
2023−99.25%
2022−75.29%
2021−35.61%
2020−51.02%
2019+66.87%
2018+0.94%
2017+263.64%
2016 (partial year)−78.80%

As of September 4, 2026.

AVTX Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$59.00K−$78.26M−132642.4%
2024$441.00K−$35.13M−7965.8%
2023$1.92M−$31.54M−1639.5%
2022$18.05M−$41.66M−230.8%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$59.00K$59.00K−$72.93M−$78.26M−132642.4%
2024$441.00K$807.00K−$40.87M−$35.13M−7965.8%
2023$1.92M$640.00K−$23.44M−$31.54M−1639.5%
2022$18.05M$14.62M−$37.44M−$41.66M−230.8%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

AVTX Valuation vs Biotechnology Median

Median of 656 stocks
MetricAVTXBiotechnology medianvs median
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Avalo Therapeutics, Inc. (AVTX) is capitalised at $1.03B on the latest close. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 33.

Over the past 52 weeks the price has ranged from $9.54 to $24.27. AVTX last closed at $19.23 on September 4, 2026. That is +$0.23 (+1.21%) against the previous close. The latest close sits 101.57% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $59.00K. Against the prior fiscal year total of $441.00K, that is a change of −86.62%. The same year closed with a net loss of $78.26M. Profit margin runs at 0%. Earnings per share on a trailing basis come to −4.46.

Across the 4 fiscal years on file, revenue moves from $18.05M in 2022 to $59.00K in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Beta against the wider market is reported at 0.79. Daily returns over the trailing 10 years annualize to a volatility of 165.09%. Over the trailing twelve months the price has returned +89.27%. Measured over 10 years, that is −47.13% a year compounded.

Growth & Income

No dividend is on file for AVTX.

Across the complete calendar years on file, 2017 returned +263.64% and 2023 returned −99.25%. Of the 9 complete calendar years on file, 4 finished higher. So far in 2026 the price is +5.89%.

Peer Comparison

Avalo Therapeutics, Inc. (AVTX) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Avalo Therapeutics, Inc. AVTX $1.03B
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Avalo Therapeutics, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Avalo Therapeutics, Inc.

Avalo Therapeutics, Inc., a clinical stage biotechnology company, develops IL-1ß-based treatments for immune-mediated inflammatory diseases in the Unites States. Its lead product includes AVTX-009, a humanized monoclonal antibody that binds to interleukin-1ß, which is in phase 2 clinical trial to treat inflammatory diseases. The company was formerly known as Cerecor Inc. and changed its name to Avalo Therapeutics, Inc. in August 2021. Avalo Therapeutics, Inc. was incorporated in 2011 and is headquartered in Wayne, Pennsylvania.

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