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NASDAQ · Biotechnology · USD

Actuate Therapeutics, Inc. Common stock (ACTU) Stock Analysis

Actuate Therapeutics, Inc. Common stock (ACTU) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

ACTU

$0.56

−$0.05 (−8.75%)

Oct 21, 2026 · Market close

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Price History

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ACTU Key Statistics

As of Oct 21, 2026
Trading
Open
$0.60
Previous Close
$0.62
Day's Range
0.56–0.64
52-Week Range
0.41–7.90
Volume
220.37K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.20
Valuation
Market Cap
$13.50M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.87
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$22.23M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
24.01M
1-Year Return
−92.34%
Dividend and dates
Earnings Date
November 12, 2026estimated
Avg Volume
351.19K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, ACTU closed at $0.56, −92.34% over 1 year.

Actuate Therapeutics, Inc. Common stock (ACTU) has a market capitalization of $13.50M.

In fiscal 2025, ACTU reported revenue of $0.00.

ACTU Stock Return by Calendar Year

Actuate Therapeutics, Inc. Common stock (ACTU) return since Aug 2024: what $10,000 became

1 year
$10,000 $766
−92.34%
Since Aug 2024
$10,000 $653
−93.47%

If you had invested $10,000 in Actuate Therapeutics, Inc. Common stock (ACTU) at the close on August 13, 2024, the earliest close on record here, it would have been worth $653 at the close on October 21, 2026: −93.47% in total, −71.28% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−90.81%
2025−23.12%
2024 (partial year)−7.55%

As of October 21, 2026.

ACTU Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$22.23M—
2024$0.00−$27.29M—
2023$0.00−$24.74M—
2022$0.00−$20.16M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$22.50M−$22.23M—
2024$0.00—−$25.16M−$27.29M—
2023$0.00—−$24.97M−$24.74M—
2022$0.00—−$20.21M−$20.16M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Actuate Therapeutics, Inc. Common stock (ACTU) at $13.50M. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 12 employees.

The 52-week range on file runs from $0.41 to $7.90. ACTU last closed at $0.56 on October 21, 2026. That is −$0.05 (−8.75%) against the previous close. The latest close sits 37.12% above that 52-week low.

Financial Health

In fiscal 2025, Actuate Therapeutics, Inc. Common stock reported revenue of $0.00. The same year closed with a net loss of $22.23M. Trailing earnings per share are −0.87.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Beta against the wider market is reported at 1.2. Annualized volatility over the trailing 2 years is 99.2%. The trailing one-year total return is −92.34%. The stored price history starts on August 13, 2024, and the total return since then is −93.47%.

Growth & Income

No dividend is on file for ACTU.

The record holds one complete calendar year, 2025, which returned −23.12%. So far in 2026 the total return is −90.81%.

Peer Comparison

Actuate Therapeutics, Inc. Common stock (ACTU) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Actuate Therapeutics, Inc. Common stock ACTU $13.50M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Actuate Therapeutics, Inc. Common stock has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Actuate Therapeutics, Inc. Common stock

Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancers in the United States. The company's lead product candidate is elraglusib injection, a glycogen synthase kinase-3 inhibitor that is in Phase 2 trial to treat metastatic pancreatic ductal adenocarcinoma. It also develops elraglusib, which is in Phase 1/2 trial for the treatment of refractory pediatric malignancies, including Ewing sarcoma, as well as neuroblastoma and pediatric leukemias. The company was formerly known as Apotheca Therapeutics, Inc. and changed its name to Actuate Therapeutics, Inc. in October 2015. Actuate Therapeutics, Inc. was incorporated in 2015 and is headquartered in Fort Worth, Texas.

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