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NASDAQ · Biotechnology · USD

Unicycive Therapeutics, Inc. (UNCY) Stock Analysis

Unicycive Therapeutics, Inc. (UNCY) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

UNCY

$5.16

−$0.14 (−2.64%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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UNCY Key Statistics

As of Sep 4, 2026
Trading
Open
$5.24
Previous Close
$5.30
Day's Range
5.12–5.24
52-Week Range
3.71–8.74
Volume
492.90K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.78
Valuation
Market Cap
$141.35M
P/E Ratio
unprofitable
Forward P/EShare price divided by forecast earnings for the year ahead, rather than the year just past.
3.65
EPS (ttm)Profit attributable to each share over the last twelve months.
−1.71
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$26.56M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
27.39M
1-Year Return
+19.44%
Dividend and dates
Earnings Date
November 12, 2026estimated
Avg Volume
1.51M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

UNCY Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−10.57%
2025−27.33%
2024−8.53%
2023+60.74%
2022−73.79%
2021 (partial year)−58.80%

As of September 4, 2026.

UNCY Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$26.56M—
2024$0.00−$36.73M—
2023$675.00K−$30.54M−4525.0%
2022$951.00K−$18.06M−1898.8%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$29.52M−$26.56M—
2024$0.00—−$32.12M−$36.73M—
2023$675.00K—−$20.77M−$30.54M−4525.0%
2022$951.00K—−$18.05M−$18.06M−1898.8%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

UNCY Valuation vs Biotechnology Median

Median of 656 stocks
MetricUNCYBiotechnology medianvs median
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Unicycive Therapeutics, Inc. (UNCY) carries a market capitalisation of $141.35M. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 21 employees.

The 52-week range on file runs from $3.71 to $8.74. The most recent close on file for UNCY is $5.16, dated September 4, 2026. That is −$0.14 (−2.64%) against the previous close. The latest close sits 39.08% above that 52-week low.

Financial Health

The most recent full year on file, fiscal 2025, shows revenue of $0.00. The same year closed with a net loss of $26.56M. The reported profit margin is 0%. Earnings per share on a trailing basis come to −1.71.

Across the 4 fiscal years on file, revenue moves from $951.00K in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative. The forward P/E on file is 3.65.

The trailing one-year price return is +19.44%. Across 5 years the annualized return works out at −28.34%. The reported beta is 1.78. Annualized volatility over the trailing 5 years is 118.72%.

Growth & Income

No dividend is on file for UNCY.

So far in 2026 the price is −10.57%. The strongest complete calendar year on file is 2023 at +60.74%; the weakest is 2022 at −73.79%. Of the 4 complete calendar years on file, 1 finished higher.

Peer Comparison

Unicycive Therapeutics, Inc. (UNCY) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Unicycive Therapeutics, Inc. UNCY $141.35M —
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Unicycive Therapeutics, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Unicycive Therapeutics, Inc.

Unicycive Therapeutics, Inc., a clinical-stage biotechnology company, identifies, develops, and commercializes therapies for the treatment of kidney diseases in the United States. It develops oxylanthanum carbonate, a lanthanum-based phosphate binding agent, which is for the treatment of hyperphosphatemia in patients with chronic kidney disease on dialysis; and UNI-494, a nicotinamide ester derivative and a selective ATP-sensitive mitochondrial potassium channel activator, which is in Phase I clinical trial for the treatment of acute kidney injury and pre-clinical stage for the treatment of chronic kidney disease. The company was incorporated in 2016 and is headquartered in Mountain View, California.

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