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TScan Therapeutics, Inc. (TCRX) Stock Analysis

Healthcare

TScan Therapeutics, Inc.

$1.07

+$0.01 (+0.94%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

TScan Therapeutics, Inc. operates as a clinical-stage biotechnology company dedicated to developing T cell receptor-engineered T cell (TCR-T) therapies specifically for treating cancer patients within the United States. The firm functions within the broader Healthcare sector and the specialized Biotechnology industry, positioning itself to address high-value therapeutic needs through innovative cell engineering. The company's financial scale is characterized by a market capitalization of $56.25M and annual revenue of $10.32M, supported by an organizational structure comprising 142 employees. These valuation and revenue figures indicate that TScan Therapeutics is a small-cap entity with a relatively modest revenue base, typical for early-stage biotechnology firms that prioritize clinical development over immediate profitability.

Financial Health

The company reported revenue of $10.32M over the trailing twelve months, yet this generated a net income of -$129,766,000 and an EBITDA of -$130,947,000, revealing a cost structure where expenses significantly exceed operational revenue. The resulting free cash flow of -$97,246,752 underscores a capital-intensive business model where cash burn is substantial, limiting immediate financial flexibility for expansion without external funding. Marginal performance is stark across all metrics, with a gross margin of 0.0%, an operating margin of -851.5%, and a profit margin of 0.0%, indicating that the company is not yet generating profit from its core operations or sales. On the balance sheet, the company holds $152.41M in cash against $94.14M in debt, resulting in a debt-to-equity ratio of 76.46, which suggests a leveraged position despite the high absolute cash balance. Liquidity is robust in the short term, evidenced by a current ratio of 8.41, which implies the company possesses ample current assets to cover its short-term obligations. Return metrics reflect the developmental stage, with a return on equity of -71.3% and a return on assets of -27.9%, demonstrating that management has not yet achieved positive returns on the capital invested in the business.

Valuation Assessment

Valuation metrics for TScan Therapeutics reflect its lack of profitability, with a trailing P/E ratio of N/A and a forward P/E of -1.29, implying that traditional earnings-based valuation models are not currently applicable due to negative earnings projections. The price-to-book ratio stands at 0.46, indicating that the market values the company's equity at a significant discount relative to its book value, a common characteristic for distressed or pre-revenue biotech firms. Alternative valuation measures such as the price-to-sales ratio of 5.45 and an EV/EBITDA of 0.01 provide context for investors analyzing the company based on revenue multiples rather than earnings power. Price action over the last year has seen the stock trade between a 52-week high of $2.57 and a 52-week low of $0.88, placing the current valuation within a wide historical range that reflects high market volatility. The stock exhibits a beta of 1.03, suggesting that its price volatility moves in tandem with, or slightly more than, the broader market, making it a non-defensive holding for portfolios seeking exposure to high-risk biotechnology innovation.

Growth & Income

Revenue growth for the year-over-year period reached 286.0%, while earnings growth is listed as N/A, illustrating a scenario where revenue expansion is occurring while profitability remains absent due to high clinical and operational costs. As a non-dividend payer, the company does not distribute a dividend yield or maintain a payout ratio, as evidenced by the 0.0% payout ratio, meaning all available cash resources are reinvested into research and development rather than returned to shareholders. This reinvestment strategy is standard for clinical-stage companies that must allocate capital to advance their lead product, TSC-101, through clinical trials to achieve commercial approval. The overall growth and income profile is defined by aggressive top-line expansion coupled with a complete lack of current earnings or dividend income, creating a high-risk, high-potential reward dynamic typical of the biotechnology sector.

Peer Comparison

TScan Therapeutics, Inc. (TCRX) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
TScan Therapeutics, Inc. TCRX $69.93M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. TScan Therapeutics, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About TScan Therapeutics, Inc.

TScan Therapeutics, Inc., a clinical-stage biotechnology company, develops T cell receptor-engineered T cell (TCR-T) therapies for the treatment of patients with cancer in the United States. The company's lead product is TSC-101, for the treatment of patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and acute lymphoblastic leukemia (ALL) in patients undergoing allogeneic hematopoietic cell transplantation (HCT), which is in Phase I clinical trial, as well as eliminates residual disease and promotes donor chimerism. It also develops TSC-102-A01 and TSC-102-A03, which are allogeneic and donor-derived TCR-T therapy candidates targeting epitopes. In addition, the company develops TSC-200, TSC-201, TSC-202, TSC-203, and TSC-204 for the treatment of solid tumors. It has a research collaboration and license agreement with Amgen Inc. to identify antigens recognized by T cells in patients with Crohn's disease. TScan Therapeutics, Inc. was incorporated in 2018 and is headquartered in Waltham, Massachusetts.

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Key Statistics

Market Cap
$69.93M
P/E Ratio
N/A
52-Week High
$2.57
52-Week Low
$0.88
Avg Volume
899.49K
Beta
1.06

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
142