StockVS

uniQure N.V. (QURE) Stock Analysis

Healthcare

uniQure N.V.

$25.15

+$0.96 (+3.97%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

uniQure N.V. specializes in the development of therapeutic treatments designed for patients suffering from rare and other devastating diseases within the United States market. The company operates within the healthcare sector, specifically targeting the biotechnology industry where it focuses on innovative solutions to lower bleeding risks for individuals living with hemophilia B through its lead product candidate, AMT-130. As of the latest reporting period, the organization employs 221 individuals and maintains a market capitalization of $958.26M with annual revenue reaching $16.10M. These financial figures indicate that the company functions as a mid-cap biotechnology entity with a significant market capitalization relative to its revenue, suggesting a valuation that places a premium on future potential rather than current earnings power.

Financial Health

The company reported revenue of $16.10M for the trailing twelve months, while net income stood at a loss of $198,971,008 and EBITDA was negative $164,343,008. The substantial gap between the modest revenue of $16.10M and the net loss of $198,971,008 reveals an aggressive cost structure typical of early-stage biotechnology firms that incur high research and development expenses before achieving commercial profitability. Free cash flow for the period was negative $106,758,000, indicating that the company is currently burning cash to fund its operations and development pipeline rather than generating liquidity from its core business activities. All three margin metrics reflect this developmental stage, with a gross margin of 0.0%, an operating margin of -900.9%, and a profit margin of 0.0%, which collectively indicate that the company has not yet established a profitable economic model. The balance sheet shows a cash position of $622.54M against total debt of $536.59M, resulting in a debt-to-equity ratio of 269.78. Despite the high leverage indicated by the debt-to-equity ratio of 269.78, the company holds more cash than debt, suggesting a conservative liquidity position regarding its immediate solvency obligations. The current ratio is reported at 10.43, which indicates an extremely strong ability to meet short-term liabilities with its current assets. Return on Equity stands at -207.1% and return on assets is -16.2%, metrics that reveal that the company is currently destroying value from an accounting perspective due to the heavy losses incurred during its product development phase.

Valuation Assessment

The valuation metrics present a complex picture, with a P/E ratio (TTM) listed as N/A and a forward P/E of -5.68. The difference between a non-existent trailing P/E and a negative forward P/E implies that the market is pricing the stock based on future expectations of earnings recovery or sustained losses, as traditional price-to-earnings multiples cannot be applied to a loss-making entity. The price-to-book ratio is 4.80, which indicates that the market is valuing the company at a significant premium over its book value, reflecting high expectations for the success of its pipeline assets. Alternative valuation measures such as the price-to-sales ratio of 59.53 and an EV/EBITDA of -5.60 suggest that investors are assigning a high multiple to every dollar of sales, prioritizing the potential of the gene therapy platform over current financial performance. The stock has a 52-week high of $71.50 and a 52-week low of $7.76, meaning the current trading price sits significantly below the yearly peak while remaining well above the yearly trough. The beta value is 0.77, which suggests that the stock price exhibits lower volatility relative to the broader market, moving less dramatically than the overall index despite its high valuation multiple.

Growth & Income

Revenue growth year-over-year is recorded at 6.6%, while earnings growth is N/A due to the company's net loss position. The absence of earnings growth compared to the positive revenue growth implies that while sales are expanding, the costs associated with generating those sales and developing the product are outpacing revenue expansion, preventing profitability. As the company does not pay a dividend, with a dividend yield of N/A and a payout ratio of 0.0%, it reinvests all available earnings and cash flow directly back into research and development rather than distributing income to shareholders. This strategy prioritizes long-term growth in the biotechnology sector over immediate income generation for investors, utilizing its substantial cash reserves to fuel the development of treatments for rare diseases.

Peer Comparison

uniQure N.V. (QURE) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
uniQure N.V. QURE $1.59B N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. uniQure N.V. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About uniQure N.V.

uniQure N.V. develops treatments for patients suffering from rare and other devastating diseases in the United States. The company offers HEMGENIX that allows people living with hemophilia B to produce factor IX, which can lower the risk of bleeding. Its lead product candidate is AMT-130, a gene therapy candidate, which is in Phase I/II clinical study for the treatment of Huntington's disease. The company also develops AMT-260, which is in Phase I/IIa clinical trial for the treatment of mesial temporal lobe epilepsy; AMT-162, which is in Phase I/IIa clinical trial to treat superoxide dismutase enzyme-amyotrophic lateral sclerosis; and AMT-191, an investigational gene therapy candidate which is in phase I/IIa clinical trial for the treatment of fabry disease. It has a licensing agreement with Apic Bio to develop, manufacture, and commercialize intrathecally administered investigational gene therapy for ALS caused by mutations in SOD-1; and development and commercial supply agreement with CLS Bhering. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.

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Key Statistics

Market Cap
$1.59B
P/E Ratio
N/A
52-Week High
$71.50
52-Week Low
$8.73
Avg Volume
2.97M
Beta
0.87

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
Netherlands
Employees
221