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StockVS

NASDAQ · Biotechnology · USD

PolyPid Ltd. (PYPD) Stock Analysis

PolyPid Ltd. (PYPD) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

PYPD

$5.07

−$0.08 (−1.55%)

Oct 21, 2026 · Market close

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Price History

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PYPD Key Statistics

As of Oct 21, 2026
Trading
Open
$5.19
Previous Close
$5.15
Day's Range
5.00–5.21
52-Week Range
3.10–5.73
Volume
136.73K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.38
Valuation
Market Cap
$102.98M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−1.44
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$34.17M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
20.31M
1-Year Return
+57.45%
Dividend and dates
Earnings Date
November 11, 2026
Avg Volume
132.32K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, PYPD closed at $5.07, +57.45% over 1 year.

PolyPid Ltd. (PYPD) has a market capitalization of $102.98M.

In fiscal 2025, PYPD reported revenue of $0.00.

PYPD Stock Return by Calendar Year

PolyPid Ltd. (PYPD) return since Jun 2020: what $10,000 became

1 year
$10,000 $15,745
+57.45%
5 years
$10,000 $221
−97.79%
Since Jun 2020
$10,000 $89
−99.11%

If you had invested $10,000 in PolyPid Ltd. (PYPD) at the close on June 26, 2020, the earliest close on record here, it would have been worth $89 at the close on October 21, 2026: −99.11% in total, −52.64% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+16.82%
2025+42.76%
2024−20.00%
2023−81.85%
2022−87.84%
2021−42.02%
2020 (partial year)−47.89%

As of October 21, 2026.

PYPD Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$34.17M—
2024$0.00−$29.02M—
2023$0.00−$23.87M—
2022$0.00−$39.56M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$32.97M−$34.17M—
2024$0.00—−$28.03M−$29.02M—
2023$0.00—−$22.87M−$23.87M—
2022$0.00—−$38.89M−$39.56M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

All 10 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

PolyPid Ltd. (PYPD) is capitalised at $102.98M on the latest close. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 69.

PYPD last closed at $5.07 on October 21, 2026. That is −$0.08 (−1.55%) against the previous close. The 52-week range on file runs from $3.10 to $5.73. The latest close sits 63.55% above that 52-week low.

Financial Health

In fiscal 2025, PolyPid Ltd. reported revenue of $0.00. The same year closed with a net loss of $34.17M. Earnings per share on a trailing basis come to −1.44.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Over the trailing twelve months the total return is +57.45%. Across 5 years the annualized return works out at −53.34%. The reported beta is 1.38. Daily returns over the trailing 6 years annualize to a volatility of 83.01%.

Growth & Income

No dividend is on file for PYPD.

Across the complete calendar years on file, 2025 returned +42.76% and 2022 returned −87.84%. Of the 5 complete calendar years on file, 1 finished higher. So far in 2026 the total return is +16.82%.

Peer Comparison

PolyPid Ltd. (PYPD) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
PolyPid Ltd. PYPD $102.98M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. PolyPid Ltd. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About PolyPid Ltd.

PolyPid Ltd., a biopharmaceutical company, developing targeted, locally administered, and prolonged-release therapeutics using its proprietary polymer-lipid encapsulation matrix (PLEX) technology to address unmet medical needs. Its lead product candidate is D-PLEX100, which is in a pivotal Phase 3 confirmatory trial for prevention of surgical site infections (SSIs) in patients undergoing abdominal colorectal surgery with large incisions. The company is also developing OncoPLEX, which is in preclinical stage for the treatment of intra-tumoral cancer. The company has a research and development collaboration with ImmunoGenesis, Inc. for the development of formulations to treat solid tumors. PolyPid Ltd. was incorporated in 2008 and is headquartered in Petah Tikva, Israel.

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