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NASDAQ · Biotechnology · USD

Plus Therapeutics, Inc. (PSTV) Stock Analysis

Plus Therapeutics, Inc. (PSTV) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

PSTV

$3.84

−$0.02 (−0.57%)

Last trade August 7, 2026

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Price History

Hover for the daily close. The dotted line marks the period open.

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PSTV Key Statistics

As of Aug 7, 2026
Trading
Open
$3.78
Previous Close
$3.86
Day's Range
3.77–3.96
52-Week Range
2.90–23.43
Volume
67.47K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.42
Valuation
Market Cap
$26.64M
P/E Ratio
0.18
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
5.14
EPS (ttm)Profit attributable to each share over the last twelve months.
21.56
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$22.39M
Profit marginThe share of revenue left as profit after all costs and taxes.
−230.24%
1-Year Return
−79.77%
Dividend and dates
Avg Volume
159.34K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

PSTV Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−70.03%
2025−55.45%
2024−34.29%
2023−63.19%
2022−69.81%
2021−48.02%
2020−15.83%
2019−83.45%
2018−90.38%
2017−80.03%
2016 (partial year)−26.70%

As of August 7, 2026.

PSTV Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$22.39M
2024$0.00−$12.98M
2023$0.00−$13.32M
2022$0.00−$20.28M
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00−$15.30M−$22.39M
2024$0.00−$14.70M−$12.98M
2023$0.00−$13.32M−$13.32M
2022$0.00−$19.71M−$20.28M

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

PSTV Valuation vs Biotechnology Median

Median of 656 stocks
MetricPSTVBiotechnology medianvs median
P/E0.1812.570.0x the median
P/S ratio5.1415.2666% below
Profit margin−230.24%0.00%230.2 pts below

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Plus Therapeutics, Inc. (PSTV) at $26.64M. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 28 employees.

The 52-week range on file runs from $2.90 to $23.43. PSTV last closed at $3.84 on August 7, 2026. That is −$0.02 (−0.57%) against the previous close. The latest close sits 32.34% above that 52-week low.

Financial Health

The most recent full year on file, fiscal 2025, shows revenue of $0.00. The same year closed with a net loss of $22.39M. The reported profit margin is −230.24%. That is 230.2 percentage points below the Biotechnology median of 0%. Earnings per share on a trailing basis come to 21.56.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

On trailing earnings, the shares are priced at 0.18 times earnings. That is 0 times the Biotechnology median of 12.57. The price-to-sales ratio is 5.14. On price-to-sales that is 66.32% below the Biotechnology median of 15.26. 656 Biotechnology companies report these metrics, and the medians quoted come from that group.

Beta against the wider market is reported at 1.42. Annualized volatility over the trailing 10 years is 183.98%. Over the trailing twelve months the price has returned −79.77%. Measured over 10 years, that is −68.40% a year compounded.

Growth & Income

No dividend is on file for PSTV.

The strongest complete calendar year on file is 2020 at −15.83%; the weakest is 2018 at −90.38%. Of the 9 complete calendar years on file, 0 finished higher. So far in 2026 the price is −70.03%.

Peer Comparison

Plus Therapeutics, Inc. (PSTV) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Plus Therapeutics, Inc. PSTV $26.64M 0.2
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Plus Therapeutics, Inc. trades at a P/E of 0.2.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of August 7, 2026.

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About Plus Therapeutics, Inc.

Plus Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. The company's lead radiotherapeutic candidate is rhenium obisbemeda, a patented radiotherapy for patients with central nervous system and other cancers, including recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers. It also develops Rhenium-188 NanoLiposome Biodegradable Alginate Microsphere to treat various solid organ cancers, such as primary and secondary liver cancers by intra-arterial injection. In addition, it develops and commercializes laboratory-developed tests comprising the CNSide Test to identify tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas. The company was formerly known as Cytori Therapeutics, Inc. and changed its name to Plus Therapeutics, Inc. in July 2019. Plus Therapeutics, Inc. was founded in 1996 and is headquartered in Houston, Texas.

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