StockVS

Vaxcyte, Inc. (PCVX) Stock Analysis

Healthcare

Vaxcyte, Inc.

$50.11

+$2.81 (+5.94%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Vaxcyte, Inc. operates as a clinical-stage vaccine innovation company dedicated to the development of conjugate and novel protein vaccines designed to prevent or treat bacterial infectious diseases. The firm functions within the broader healthcare sector, specifically targeting the biotechnology industry where it focuses on creating immunological solutions for specific pathogens. Currently, the company employs 507 individuals and holds a reported market capitalization of $7.84 billion. While the company reports a market cap of $7.84 billion, the annual revenue figure is not available in the provided financial data, indicating that valuation is currently driven by pipeline potential rather than established sales streams. This disparity between the substantial market capitalization and the lack of reported revenue suggests the company is in a pre-commercialization phase where investor sentiment is priced based on future clinical trial outcomes and regulatory pathways rather than current cash generation. The scale of the organization, evidenced by its workforce size and market cap, positions it as a significant entity within the biotechnology space despite the absence of traditional earnings metrics.

Financial Health

The company's financial statements reflect a pre-revenue or early-stage commercial profile, as revenue for the trailing twelve months is not available in the provided data. Consequently, the net income stands at a loss of $-766,627,968, and the EBITDA is reported at $-907,278,976, highlighting the heavy capital expenditure required for clinical research and development. The gap between the non-existent revenue and the substantial net loss reveals a cost structure dominated by R&D expenses, personnel costs, and clinical trial overheads rather than cost of goods sold. Free cash flow is reported at $-430,852,864, which indicates a current lack of financial flexibility for capital returns but demonstrates the company is consuming cash to fuel its innovation pipeline. All three margin metrics—gross margin, operating margin, and profit margin—are listed as 0.0%, which is consistent with a company that has not yet generated meaningful commercial sales to establish a margin profile. On the liability side, the company holds $1.56 billion in cash against $117.48 million in debt, resulting in a debt-to-equity ratio of 4.38. Although the debt-to-equity ratio is numerically high, the substantial cash balance provides a robust buffer, suggesting the balance sheet is less leveraged in a risk sense than the ratio implies. The current ratio stands at 7.91, a figure that indicates strong short-term liquidity and a significant excess of current assets over current liabilities. Return on Equity is negative at -25.6% and Return on Assets is negative at -17.7%, metrics that reveal that management is currently generating losses relative to the capital invested in the company.

Valuation Assessment

The trailing twelve-month P/E ratio is not available due to the lack of earnings, while the forward P/E is reported at -7.41, implying that the market prices the stock based on anticipated future profitability rather than historical performance. The price-to-book ratio is 2.63, indicating that the market values the company at a premium of 163% over its net book value, likely reflecting the high value placed on its intellectual property and clinical pipeline. The price-to-sales ratio is not available in the provided facts, and the EV/EBITDA stands at -6.97, which is a negative multiple typical of early-stage biotechnology firms that have not yet reached profitability. The stock has traded within a 52-week range between a low of $27.66 and a high of $76.61. Without a specific current price in the provided data, the position relative to this range cannot be calculated, but the volatility suggests significant market movement over the past year. The beta value is 1.38, which indicates that the stock price is expected to be 38% more volatile than the broader market, exposing investors to higher fluctuations during periods of market stress.

Growth & Income

The revenue growth year-over-year and earnings growth year-over-year are both listed as not available in the provided financial facts, meaning historical growth trajectories cannot be quantified from this dataset. Since the company does not pay a dividend, the dividend yield is not available and the payout ratio is 0.0%, indicating that all available cash flow is retained within the company to fund operations and research. This reinvestment strategy is standard for clinical-stage biotechnology firms, where earnings are channeled back into the development of new vaccine candidates rather than distributed to shareholders. The overall growth and income profile is characterized by a complete absence of current income generation, with the company relying entirely on external capital markets and its existing cash reserves to sustain operations until commercialization milestones are achieved.

Peer Comparison

Vaxcyte, Inc. (PCVX) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Vaxcyte, Inc. PCVX $6.83B N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Vaxcyte, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Vaxcyte, Inc.

Vaxcyte, Inc., a clinical-stage vaccine innovation company, develops conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent carrier-sparing investigational pneumococcal conjugate vaccine (PCV) for the prevention of invasive pneumococcal disease (IPD) in infants. The company also develops VAX-31, a 31-valent, carrier-sparing investigational PCV for the prevention of IPD in adults and children; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting the keystone pathogen responsible for periodontitis; VAX-GI, a novel preclinical vaccine candidate for the treatment of dysentery and shigellosis, which is caused by Shigella bacteria; and VAX-XL, a third-generation pneumococcal conjugate vaccine. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.

Visit website →

Key Statistics

Market Cap
$6.83B
P/E Ratio
N/A
52-Week High
$65.00
52-Week Low
$29.08
Avg Volume
1.42M
Beta
1.30

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
507