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StockVS

NASDAQ · Biotechnology · USD

Omeros Corporation (OMER) Stock Analysis

Omeros Corporation (OMER) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

OMER

$16.26

−$0.29 (−1.75%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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OMER Key Statistics

As of Oct 21, 2026
Trading
Open
$16.56
Previous Close
$16.55
Day's Range
16.21–16.67
52-Week Range
6.24–21.24
Volume
698.11K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.57
Valuation
Market Cap
$1.18B
P/E Ratio
13.33
Forward P/EShare price divided by forecast earnings for the year ahead, rather than the year just past.
13.22
PEG RatioThe P/E ratio divided by the expected earnings growth rate. It puts a high P/E in the context of how fast profits are growing.
0.81
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
30.63
EPS (ttm)Profit attributable to each share over the last twelve months.
1.22
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$3.35M
Profit marginThe share of revenue left as profit after all costs and taxes.
324.88%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
72.39M
1-Year Return
+106.61%
Dividend and dates
Earnings Date
November 12, 2026estimated
Avg Volume
1.74M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, OMER closed at $16.26, +106.61% over 1 year.

Omeros Corporation (OMER) has a market capitalization of $1.18B.

In fiscal 2025, OMER reported revenue of $0.00.

OMER Stock Return by Calendar Year

Omeros Corporation (OMER) 10-year return: what $10,000 became

1 year
$10,000 $20,661
+106.61%
5 years
$10,000 $25,170
+151.70%
10 years
$10,000 $19,085
+90.85%

If you had invested $10,000 in Omeros Corporation (OMER) 10 years ago, at the close on October 21, 2016, it would have been worth $19,085 at the close on October 21, 2026: +90.85% in total, +6.68% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−5.36%
2025+73.89%
2024+202.14%
2023+44.69%
2022−64.85%
2021−55.00%
2020+1.42%
2019+26.48%
2018−42.67%
2017+95.87%
2016 (partial year)−20.64%

As of October 21, 2026.

OMER Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$3.35M—
2024$0.00−$156.82M—
2023$0.00−$117.81M—
2022$0.00$47.42M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$122.80M−$3.35M—
2024$0.00—−$166.95M−$156.82M—
2023$0.00—−$164.53M−$117.81M—
2022$0.00—−$163.39M$47.42M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

OMER Valuation vs Biotechnology Median

Median of 608 stocks
MetricOMERBiotechnology medianvs median
P/E13.3316.6020% below
P/S ratio30.6313.30130% above
Profit margin324.88%−38.31%363.2 pts above

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 17 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Omeros Corporation (OMER) at $1.18B. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 175 employees.

The 52-week range on file runs from $6.24 to $21.24. OMER last closed at $16.26 on October 21, 2026. That is −$0.29 (−1.75%) against the previous close. The latest close sits 160.58% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $3.35M. Profit margin runs at 324.88%. That is 363.2 percentage points above the Biotechnology median of −38.31%. Trailing earnings per share are 1.22.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 1 report positive net income.

Valuation Assessment

The trailing P/E ratio stands at 13.33. That is 19.7% below the Biotechnology median of 16.6. The forward P/E on file is 13.22. The PEG ratio, which sets the P/E against expected earnings growth, reads 0.81. Measured against sales, the shares trade at 30.63 times revenue. On price-to-sales that is 130.36% above the Biotechnology median of 13.3. The medians here are taken across 608 Biotechnology companies that report the metric.

Beta against the wider market is reported at 2.57. Annualized volatility over the trailing 10 years is 111.69%. The trailing one-year total return is +106.61%. Across 10 years the annualized return works out at +6.68%.

Growth & Income

The record shows no dividend for OMER.

So far in 2026 the total return is −5.36%. Across the complete calendar years on file, 2024 returned +202.14% and 2022 returned −64.85%. Of the 9 complete calendar years on file, 6 finished higher.

Peer Comparison

Omeros Corporation (OMER) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Omeros Corporation OMER $1.18B 13.3
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Omeros Corporation trades at a P/E of 13.3.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Omeros Corporation

Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory distress syndrome. It also develops OMS1029 that has completed phase I clinical trials for mannan-binding lectin-associated serine protease 2 (MASP-2) and lectin pathway disorders; and OMS527 that is in phase I clinical trials for addictions and compulsive disorders, and movement disorders, as well as cocaine use disorder. In addition, the company's products under preclinical development comprise MASP-2, a pro-inflammatory protein target for the treatment of lectin pathway disorders; MASP-3 small-molecule inhibitors for alternative pathway disorders; OncotoX-AML, to treat acute myeloid leukemia; and Targeted Complement Activating Therapy, for Multidrug-resistant organisms. Omeros Corporation was incorporated in 1994 and is headquartered in Seattle, Washington.

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