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NYSE American · Biotechnology · USD

Oragenics, Inc. (OGEN) Stock Analysis

Oragenics, Inc. (OGEN) is a Biotechnology stock listed on NYSE American and quoted in US Dollar.

Last Updated: October 21, 2026

OGEN

$0.41

−$0.02 (−4.88%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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OGEN Key Statistics

As of Oct 21, 2026
Trading
Open
$0.44
Previous Close
$0.43
Day's Range
0.41–0.43
52-Week Range
0.41–1.36
Volume
5.33K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.26
Valuation
Market Cap
$1.86M
P/E Ratio
unprofitable
PEG RatioThe P/E ratio divided by the expected earnings growth rate. It puts a high P/E in the context of how fast profits are growing.
−8.96
EPS (ttm)Profit attributable to each share over the last twelve months.
−2.44
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$9.84M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
4.51M
1-Year Return
−69.87%
Dividend and dates
Avg Volume
29.60K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, OGEN closed at $0.41, −69.87% over 1 year.

Oragenics, Inc. (OGEN) has a market capitalization of $1.86M.

In fiscal 2025, OGEN reported revenue of $0.00.

OGEN Stock Return by Calendar Year

Oragenics, Inc. (OGEN) 10-year return: what $10,000 became

1 year
$10,000 $3,013
−69.87%
5 years
$10,000 $4
−99.96%
10 years
$10,000 $0.52
−99.99%

If you had invested $10,000 in Oragenics, Inc. (OGEN) 10 years ago, at the close on October 21, 2016, it would have been worth $0.52 at the close on October 21, 2026: −99.99% in total, −62.70% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−47.08%
2025−92.97%
2024−93.43%
2023−14.70%
2022−75.56%
2021+0.00%
2020−13.46%
2019−39.53%
2018−62.61%
2017−57.41%
2016 (partial year)−28.00%

As of October 21, 2026.

OGEN Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$9.84M—
2024$0.00−$10.57M—
2023$0.00−$20.66M—
2022$0.00−$14.29M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$9.36M−$9.84M—
2024$0.00—−$10.56M−$10.57M—
2023$0.00—−$20.90M−$20.66M—
2022$0.00—−$14.42M−$14.29M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Oragenics, Inc. (OGEN) at $1.86M. It is classified in the Biotechnology industry, within the Healthcare sector. The company reports 3 employees.

Over the past 52 weeks the price has ranged from $0.41 to $1.36. The most recent close on file for OGEN is $0.41, dated October 21, 2026. That is −$0.02 (−4.88%) against the previous close. The latest close sits 0.68% above that 52-week low.

Financial Health

The most recent full year on file, fiscal 2025, shows revenue of $0.00. The same year closed with a net loss of $9.84M. Trailing earnings per share are −2.44.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. The PEG ratio, which sets the P/E against expected earnings growth, reads −8.96.

Over the trailing twelve months the total return is −69.87%. Across 10 years the annualized return works out at −62.70%. The reported beta is 1.26. Annualized volatility over the trailing 10 years is 126.83%.

Growth & Income

No dividend is on file for OGEN.

2026 is still running; the total return is −47.08% year to date. Across the complete calendar years on file, 2021 returned 0.00% and 2024 returned −93.43%. Of the 9 complete calendar years on file, 0 finished higher.

Peer Comparison

Oragenics, Inc. (OGEN) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Oragenics, Inc. OGEN $1.86M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Oragenics, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Oragenics, Inc.

Oragenics, Inc., a development-stage company, engages in the research and development of nasal delivery pharmaceutical therapies neurological conditions and infectious diseases in the United States. Its lead product is ONP-002, a fully synthetic, non-naturally occurring neurosteroid, which is lipophilic and can cross the blood-brain barrier to reduce swelling, oxidative stress, and inflammation while restoring proper blood flow through gene amplification for the treatment of mild traumatic brain injury. The company was formerly known as Oragen, Inc. Oragenics, Inc. was incorporated in 1996 and is headquartered in Lakewood Ranch, Florida.

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