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NASDAQ · Biotechnology · USD

Oculis Holding AG (OCS) Stock Analysis

Oculis Holding AG (OCS) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

OCS

$7.87

+$0.38 (+5.07%)

Oct 21, 2026 · Market close

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Price History

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OCS Key Statistics

As of Oct 21, 2026
Trading
Open
$7.54
Previous Close
$7.49
Day's Range
7.40–8.02
52-Week Range
7.11–34.48
Volume
324.10K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
0.27
Valuation
Market Cap
$484.70M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
413.21
EPS (ttm)Profit attributable to each share over the last twelve months.
−1.74
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$98.96M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
61.59M
1-Year Return
−63.93%
Dividend and dates
Earnings Date
November 3, 2026
Avg Volume
264.76K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, OCS closed at $7.87, −63.93% over 1 year.

Oculis Holding AG (OCS) has a market capitalization of $484.70M.

In fiscal 2025, OCS reported revenue of $0.00.

OCS Stock Return by Calendar Year

Oculis Holding AG (OCS) return since May 2021: what $10,000 became

1 year
$10,000 $3,607
−63.93%
5 years
$10,000 $8,105
−18.95%
Since May 2021
$10,000 $8,113
−18.87%

If you had invested $10,000 in Oculis Holding AG (OCS) at the close on May 18, 2021, the earliest close on record here, it would have been worth $8,113 at the close on October 21, 2026: −18.87% in total, −3.78% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−60.59%
2025+17.47%
2024+51.38%
2023+11.19%
2022+4.23%
2021 (partial year)−0.10%

As of October 21, 2026.

OCS Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$98.96M—
2024$0.00−$85.78M—
2023$0.00−$88.80M—
2022$0.00−$38.70M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$81.67M−$98.96M—
2024$0.00—−$73.20M−$85.78M—
2023$0.00—−$45.85M−$88.80M—
2022$0.00—−$32.38M−$38.70M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

OCS Valuation vs Biotechnology Median

Median of 608 stocks
MetricOCSBiotechnology medianvs median
P/S ratio413.2113.3031.1x the median

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 19 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Oculis Holding AG (OCS) at $484.70M. The company sits in the Healthcare sector, in the Biotechnology industry. Headcount on file is 60.

The 52-week range on file runs from $7.11 to $34.48. The most recent close on file for OCS is $7.87, dated October 21, 2026. That is +$0.38 (+5.07%) against the previous close. The latest close sits 10.69% above that 52-week low.

Financial Health

In fiscal 2025, Oculis Holding AG reported revenue of $0.00. The same year closed with a net loss of $98.96M. Earnings per share on a trailing basis come to −1.74.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. Measured against sales, the shares trade at 413.21 times revenue. On price-to-sales that is 31.1 times the Biotechnology median of 13.3. 608 Biotechnology companies report these metrics, and the medians quoted come from that group.

Beta against the wider market is reported at 0.27. Annualized volatility over the trailing 5 years is 47.18%. Over the trailing twelve months the total return is −63.93%. Across 5 years the annualized return works out at −4.11%.

Growth & Income

The record shows no dividend for OCS.

The strongest complete calendar year on file is 2024 at +51.38%; the weakest is 2022 at +4.23%. Of the 4 complete calendar years on file, 4 finished higher. So far in 2026 the total return is −60.59%.

Peer Comparison

Oculis Holding AG (OCS) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Oculis Holding AG OCS $484.70M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Oculis Holding AG has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Oculis Holding AG

Oculis Holding AG, a clinical-stage biopharmaceutical company, develops drug candidates to treat ophthalmic, neuro-ophthalmic, and neurological diseases in Switzerland and internationally. The company's lead product candidate is OCS-01, a topical dexamethasone optireach formulation, which is in Phase 3 clinical trials for the treatment of diabetic macular edema; OCS-02, a topical biologic candidate that is in Phase 2b clinical trials for the treatment for dry eye disease; and OCS-05, a disease modifying neuroprotective agent for neurological damage with indications for glaucoma, dry age-related macular degeneration and diabetic retinopathy, and acute optic neuritis. Oculis Holding AG was formerly known as Oculis SA and changed its name to Oculis Holding AG in March 2023. The company was founded in 2017 and is based in Zug, Switzerland.

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