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NASDAQ · Biotechnology · USD

Mineralys Therapeutics, Inc. (MLYS) Stock Analysis

Mineralys Therapeutics, Inc. (MLYS) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

MLYS

$21.10

−$0.48 (−2.22%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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MLYS Key Statistics

As of Oct 21, 2026
Trading
Open
$21.74
Previous Close
$21.58
Day's Range
21.10–22.24
52-Week Range
20.12–47.65
Volume
807.79K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
0.69
Valuation
Market Cap
$1.87B
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−4.22
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$154.65M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
88.41M
1-Year Return
−51.35%
Dividend and dates
Earnings Date
November 10, 2026estimated
Avg Volume
1.13M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, MLYS closed at $21.10, −51.35% over 1 year.

Mineralys Therapeutics, Inc. (MLYS) has a market capitalization of $1.87B.

In fiscal 2025, MLYS reported revenue of $0.00.

MLYS Stock Return by Calendar Year

Mineralys Therapeutics, Inc. (MLYS) return since Feb 2023: what $10,000 became

1 year
$10,000 $4,865
−51.35%
3 years
$10,000 $25,239
+152.39%
Since Feb 2023
$10,000 $11,443
+14.43%

If you had invested $10,000 in Mineralys Therapeutics, Inc. (MLYS) at the close on February 10, 2023, the earliest close on record here, it would have been worth $11,443 at the close on October 21, 2026: +14.43% in total, +3.72% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−41.86%
2025+194.80%
2024+43.14%
2023 (partial year)−53.36%

As of October 21, 2026.

MLYS Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$154.65M—
2024$0.00−$177.81M—
2023$0.00−$71.90M—
2022$0.00−$29.80M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$170.60M−$154.65M—
2024$0.00—−$192.40M−$177.81M—
2023$0.00—−$84.66M−$71.90M—
2022$0.00—−$31.48M−$29.80M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

All 18 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Mineralys Therapeutics, Inc. (MLYS) is capitalised at $1.87B on the latest close. It is classified in the Biotechnology industry, within the Healthcare sector. The company reports 76 employees.

The most recent close on file for MLYS is $21.10, dated October 21, 2026. That is −$0.48 (−2.22%) against the previous close. Over the past 52 weeks the price has ranged from $20.12 to $47.65. The latest close sits 4.87% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $154.65M. Trailing earnings per share are −4.22.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Over the trailing twelve months the total return is −51.35%. Across 3 years the annualized return works out at +36.15%. The reported beta is 0.69. Annualized volatility over the trailing 3 years is 85.43%.

Growth & Income

The record shows no dividend for MLYS.

Across the complete calendar years on file, 2025 returned +194.80% and 2024 returned +43.14%. So far in 2026 the total return is −41.86%.

Peer Comparison

Mineralys Therapeutics, Inc. (MLYS) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Mineralys Therapeutics, Inc. MLYS $1.87B —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Mineralys Therapeutics, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Mineralys Therapeutics, Inc.

Mineralys Therapeutics, Inc., a biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States. It is developing lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor for the treatment of cardiorenal conditions affected by dysregulated aldosterone, such as hypertension, chronic kidney disease, and obstructive sleep apnea. The company was formerly known as Catalys SC1, Inc. and changed its name to Mineralys Therapeutics, Inc. in May 2020. Mineralys Therapeutics, Inc. was incorporated in 2019 and is headquartered in Radnor, Pennsylvania.

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