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StockVS

NYSE American · Medical Instruments & Supplies · USD

Milestone Scientific Inc. (MLSS) Stock Analysis

Milestone Scientific Inc. (MLSS) is a Medical Instruments & Supplies stock listed on NYSE American and quoted in US Dollar.

Last Updated: October 21, 2026

MLSS

$0.31

−$0.03 (−8.31%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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MLSS Key Statistics

As of Oct 21, 2026
Trading
Open
$0.33
Previous Close
$0.34
Day's Range
0.31–0.34
52-Week Range
0.22–0.58
Volume
129.14K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.13
Valuation
Market Cap
$28.09M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
2.98
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.04
Financials (FY)
Revenue (FY)
$8.97M+3.99%
Net Income (FY)
−$5.72M
Profit marginThe share of revenue left as profit after all costs and taxes.
−43.98%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
90.61M
1-Year Return
−31.11%
Dividend and dates
Earnings Date
November 12, 2026
Avg Volume
123.48K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, MLSS closed at $0.31, −31.11% over 1 year.

Milestone Scientific Inc. (MLSS) has a market capitalization of $28.09M.

In fiscal 2025, MLSS reported revenue of $8.97M.

MLSS Stock Return by Calendar Year

Milestone Scientific Inc. (MLSS) 10-year return: what $10,000 became

1 year
$10,000 $6,889
−31.11%
5 years
$10,000 $1,455
−85.45%
10 years
$10,000 $1,512
−84.88%

If you had invested $10,000 in Milestone Scientific Inc. (MLSS) 10 years ago, at the close on October 21, 2016, it would have been worth $1,512 at the close on October 21, 2026: −84.88% in total, −17.21% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+14.81%
2025−71.88%
2024+39.13%
2023+43.75%
2022−76.70%
2021−2.83%
2020+52.52%
2019+321.21%
2018−72.03%
2017−15.71%
2016 (partial year)−45.31%

As of October 21, 2026.

MLSS Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$8.97M−$5.72M−63.8%
2024$8.63M−$4.71M−54.6%
2023$9.83M−$6.93M−70.5%
2022$8.81M−$8.71M−98.9%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$8.97M$6.41M−$5.70M−$5.72M−63.8%
2024$8.63M$6.43M−$6.76M−$4.71M−54.6%
2023$9.83M$6.79M−$7.11M−$6.93M−70.5%
2022$8.81M$4.90M−$8.83M−$8.71M−98.9%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

MLSS Valuation vs Medical Instruments & Supplies Median

Median of 50 stocks
MetricMLSSMedical Instruments & Supplies medianvs median
P/S ratio2.982.6015% above
Profit margin−43.98%1.62%45.6 pts below

Medians across 50 Medical Instruments & Supplies stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 10 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Milestone Scientific Inc. (MLSS) carries a market capitalisation of $28.09M. It is classified in the Medical Instruments & Supplies industry, within the Healthcare sector. Headcount on file is 15.

MLSS last closed at $0.31 on October 21, 2026. That is −$0.03 (−8.31%) against the previous close. Over the past 52 weeks the price has ranged from $0.22 to $0.58. The latest close sits 40.91% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $8.97M. Against the prior fiscal year total of $8.63M, that is a change of +3.99%. The same year closed with a net loss of $5.72M. The reported profit margin is −43.98%. That is 45.6 percentage points below the Medical Instruments & Supplies median of 1.62%. Earnings per share on a trailing basis come to −0.04.

Across the 4 fiscal years on file, revenue moves from $8.81M in 2022 to $8.97M in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. The price-to-sales ratio is 2.98. On price-to-sales that is 14.78% above the Medical Instruments & Supplies median of 2.6. The medians here are taken across 50 Medical Instruments & Supplies companies that report the metric.

The reported beta is 1.13. Daily returns over the trailing 10 years annualize to a volatility of 88.01%. Over the trailing twelve months the total return is −31.11%. Measured over 10 years, that is −17.21% a year compounded.

Growth & Income

No dividend is on file for MLSS.

2026 is still running; the total return is +14.81% year to date. The strongest complete calendar year on file is 2019 at +321.21%; the weakest is 2022 at −76.70%. Of the 9 complete calendar years on file, 4 finished higher.

Peer Comparison

Milestone Scientific Inc. (MLSS) operates in the Medical Instruments & Supplies industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Milestone Scientific Inc. MLSS $28.09M —
Intuitive Surgical, Inc. ISRG $151.25B 51.8
Becton, Dickinson and Company BDX $52.79B 45.1
Medline Inc. MDLN $47.51B 88.3

The Medical Instruments & Supplies industry average P/E ratio is 31.2x. Milestone Scientific Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Milestone Scientific Inc.

Milestone Scientific Inc., a biomedical technology company, patents, designs, develops, and commercializes diagnostic and therapeutic injection technologies, and devices for medical and dental use in the United States, China, and internationally. It operates through Dental and Medical segments. The company provides the Wand, a single use disposable handpiece device for dental procedures that require local anesthetic under the CompuDent and STA Single Tooth Anesthesia System names. It also offers CompuFlo, a computer-controlled drug delivery system for the painless delivery of drugs, anesthetics, and other medicaments, as well as for the aspiration of bodily fluids or previously injected substances; and disposable injection handpiece for the tactile control during the injection. In addition, the company provides CompuFlo Epidural, a computer-controlled anesthesia system for use in various medical applications. Further, it offers CompuMed for use in various medical procedures performed in plastic, hair restoration, and colorectal surgery, as well as podiatry, dermatology, orthopedics, and various other disciplines. Milestone Scientific Inc. was incorporated in 1989 and is headquartered in Roseland, New Jersey.

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