StockVS

TSX · Biotechnology · CAD

Medicenna Therapeutics Corp. (MDNA.TO) Stock Analysis

Medicenna Therapeutics Corp. (MDNA.TO) is a Biotechnology stock listed on TSX and quoted in Canadian Dollar.

Last Updated: October 21, 2026

MDNA.TO

CA$0.41

+CA$0.02 (+5.13%)

Oct 21, 2026 · Market close

Compare

Price History

Hover for the daily close. The dotted line marks the period open.

Compare MDNA.TO with… →

MDNA.TO Key Statistics

As of Oct 21, 2026
Trading
Open
CA$0.39
Previous Close
CA$0.39
Day's Range
0.39–0.43
52-Week Range
0.34–1.97
Volume
89.29K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.10
Valuation
Market Cap
CA$37.84M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.22
Financials (FY)
Revenue (FY)
CA$0.00
Net Income (FY)
−CA$18.41M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
92.30M
1-Year Return
−56.38%
Dividend and dates
Earnings Date
November 12, 2026estimated
Avg Volume
45.30K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, MDNA.TO closed at CA$0.41, −56.38% over 1 year.

Medicenna Therapeutics Corp. (MDNA.TO) has a market capitalization of CA$37.84M.

In fiscal 2025, MDNA.TO reported revenue of CA$0.00.

MDNA.TO Stock Return by Calendar Year

Medicenna Therapeutics Corp. (MDNA.TO) return since Mar 2017: what CA$10,000 became

1 year
CA$10,000 CA$4,362
−56.38%
5 years
CA$10,000 CA$1,302
−86.98%
Since Mar 2017
CA$10,000 CA$1,519
−84.81%

If you had invested CA$10,000 in Medicenna Therapeutics Corp. (MDNA.TO) at the close on March 8, 2017, the earliest close on record here, it would have been worth CA$1,519 at the close on October 21, 2026: −84.81% in total, −17.79% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−55.43%
2025−44.24%
2024+292.86%
2023−34.38%
2022−69.52%
2021−64.71%
2020+75.00%
2019+385.71%
2018−65.00%
2017 (partial year)−25.93%

As of October 21, 2026.

MDNA.TO Revenue and Earnings by Fiscal Year

FY ends March
Fiscal yearRevenueNet incomeNet margin
2025CA$0.00−CA$18.41M—
2024CA$0.00−CA$11.81M—
2023CA$0.00−CA$25.47M—
2022CA$0.00−CA$10.05M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025CA$0.00—−CA$22.42M−CA$18.41M—
2024CA$0.00—−CA$20.41M−CA$11.81M—
2023CA$0.00—−CA$18.67M−CA$25.47M—
2022CA$0.00—−CA$16.30M−CA$10.05M—

Annual figures as reported, in the company's reporting currency. As of March 31, 2026.

Analysis

Data-derived

Company Overview

Medicenna Therapeutics Corp. (MDNA.TO) carries a market capitalisation of CA$37.84M. The company sits in the Healthcare sector, in the Biotechnology industry. Headcount on file is 15.

MDNA.TO last closed at CA$0.41 on October 21, 2026. That is +CA$0.02 (+5.13%) against the previous close. The 52-week range on file runs from CA$0.34 to CA$1.97. The latest close sits 22.39% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to CA$0.00. The same year closed with a net loss of CA$18.41M. Earnings per share on a trailing basis come to −0.22.

Across the 4 fiscal years on file, revenue moves from CA$0.00 in 2022 to CA$0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative.

The reported beta is 2.1. Annualized volatility over the trailing 9 years is 92.36%. The trailing one-year total return is −56.38%. Measured over 5 years, that is −33.49% a year compounded.

Growth & Income

The record shows no dividend for MDNA.TO.

The strongest complete calendar year on file is 2019 at +385.71%; the weakest is 2022 at −69.52%. Of the 8 complete calendar years on file, 3 finished higher. So far in 2026 the total return is −55.43%.

Peer Comparison

Medicenna Therapeutics Corp. (MDNA.TO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Medicenna Therapeutics Corp. MDNA.TO CA$37.84M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

Market caps are shown in each company's own trading currency, without conversion, and the peers are listed in order of these unconverted figures.

The Biotechnology industry average P/E ratio is 16.6x. Medicenna Therapeutics Corp. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

Related Biotechnology Stocks

View all Biotechnology stocks →

Popular Healthcare Stocks

View all Healthcare stocks →

About Medicenna Therapeutics Corp.

Medicenna Therapeutics Corp., a clinical-stage immunotherapy company, engages in the development and commercialization of Superkines and empowered Superkines for the treatment of cancer, inflammation, and immune-mediated diseases. It develops bizaxofusp, an interleukin- 4 (IL-4) targeted therapy for the treatment of recurrent glioblastoma. The company also develops MDNA11, an interleukin-2 (IL-2) to activate anti-cancer immune cells over immunosuppressive Tregs; and MDNA113, a tumor-targeting and activatable bifunctional anti-PD-1-IL-2 superkine for cancer. In addition, its preclinical products are MDNA209, an IL-2/IL-15 antagonist for autoimmune diseases, such as multiple sclerosis and graft versus host diseases, including transplant rejection; and MDNA413, an IL-4/IL-13 antagonist to inflammatory, asthma, and atopic dermatitis, as well as other allergic diseases. Medicenna Therapeutics Corp. is headquartered in Toronto, Canada.

Visit website →