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Lixte Biotechnology Holdings, Inc. (LIXT) Stock Analysis

Healthcare

Lixte Biotechnology Holdings, Inc.

$5.65

$-0.23 (-3.91%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Lixte Biotechnology Holdings, Inc. operates as a clinical-stage biopharmaceutical entity dedicated to identifying therapeutic targets for cancer drug development and commercializing associated cancer therapies. The company functions within the Healthcare sector, specifically the Biotechnology industry, where operational focus is typically directed toward early-stage research and clinical trials rather than mature product sales. As of the latest available data, Lixte Biotechnology Holdings, Inc. carries a market capitalization of $26.89M and employs a workforce of 2 individuals. The combination of a market cap under $30 million and a minimal employee count of two suggests the company is in a very early development phase with limited operational footprint, indicating that its current financial position is primarily supported by capital raised for future clinical progression rather than established commercial revenue streams.

Financial Health

The company reports no revenue over the trailing twelve months, resulting in a net income of $-4,133,687 and an EBITDA figure that is not available due to the lack of revenue operations. The substantial gap between zero revenue and a net loss exceeding four million dollars reveals a cost structure heavily weighted toward research, development, and clinical trial expenses rather than cost of goods sold. Free cash flow stands at $-3,476,484, which indicates that the company is consuming cash reserves to fund its clinical-stage activities rather than generating liquidity from operations. All three margin metrics—gross margin, operating margin, and profit margin—are recorded at 0.0%, reflecting the standard financial profile of a pre-revenue biotechnology firm where no sales have occurred to generate profitability. The balance sheet shows a cash position of $2.89M with no debt on record, as the debt and debt-to-equity ratio are not available, suggesting a conservative capital structure reliant entirely on equity financing. A current ratio of 10.42 indicates strong short-term liquidity relative to current liabilities, providing ample buffer to cover immediate obligations despite the lack of operational cash inflows. Return on Equity is -130.1% and Return on Assets is -68.3%, metrics that reflect the negative returns typical of a company investing capital into high-risk, long-term clinical development projects before achieving commercialization.

Valuation Assessment

The trailing twelve-month P/E ratio and forward P/E ratio are both not available, as these metrics cannot be calculated without reported earnings or projected profitability in a clinical-stage entity. The price-to-book ratio is 7.46, which indicates that the market values the company at a significant premium over its net asset book value, likely driven by the potential value of its pipeline assets rather than tangible current assets. Price-to-sales and EV/EBITDA are also not available given the absence of revenue and earnings data, rendering these alternative valuation metrics inapplicable for this specific asset. The stock has traded between a 52-week low of $0.64 and a 52-week high of $6.26, illustrating a wide trading range that reflects the high volatility common in small-cap biotechnology stocks. The beta value is 1.00, meaning the stock's price volatility has historically moved in line with the broader market rather than exhibiting higher or lower sensitivity to general market fluctuations.

Growth & Income

Revenue growth year-over-year and earnings growth year-over-year are not available due to the absence of historical revenue data and the current lack of profitability. Since the company has not generated revenue, there is no growth trajectory in earnings relative to sales to analyze, implying that any future earnings growth will depend entirely on the successful transition from clinical trials to commercial sales. The company does not pay dividends, evidenced by a dividend yield of N/A and a payout ratio of 0.0%, which means the company retains all available capital to reinvest into its research and development efforts rather than distributing income to shareholders. The overall growth and income profile is characterized by a complete reliance on future clinical success to generate any financial return, with no current income generation or historical growth metrics to evaluate.

Peer Comparison

Lixte Biotechnology Holdings, Inc. (LIXT) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Lixte Biotechnology Holdings, Inc. LIXT $69.96M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Lixte Biotechnology Holdings, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Lixte Biotechnology Holdings, Inc.

Lixte Biotechnology Holdings, Inc., a clinical-stage biopharmaceutical and proton cancer therapy company, focuses on identifying targets for cancer drug development, and developing and commercializing cancer therapies. Its lead product candidate, LB-100 is in phase 1b clinical trials combined with Atezolizumab for patients with microsatellite stable metastatic colorectal cancer. The company's LB-100 combined with doxorubicin in advanced soft tissue sarcoma is under Phase 1b portion; and LB-100 combined with dostarlimab that is in phase 1b/2 for ovarian clear cell carcinoma. The company has a clinical trial research agreement with the Netherlands Cancer Institute; collaboration agreement for an investigator-initiated clinical trial with the Spanish Sarcoma Group; and a development collaboration agreement with the Netherlands Cancer Institute. Lixte Biotechnology Holdings, Inc. was founded in 2005 and is based in Boca Raton, Florida.

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Key Statistics

Market Cap
$69.96M
P/E Ratio
N/A
52-Week High
$6.26
52-Week Low
$0.64
Avg Volume
56.36K
Beta
1.05

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
3