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Jazz Pharmaceuticals plc (JAZZ) Stock Analysis

Healthcare

Jazz Pharmaceuticals plc

$237.41

$-2.42 (-1.01%)

Last Updated: May 26, 2026

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Analysis

Company Overview

Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products across the United States, Europe, and international markets, offering specific therapies such as Xywav for treating cataplexy or excessive daytime sleepiness with narcolepsy and idiopathic hypersomnia, as well as Epidiolex for seizures. Operating within the healthcare sector and specifically the biotechnology industry, the company focuses on the research and commercialization of specialized medicinal products rather than broad consumer goods. The entity maintains a substantial scale with a market capitalization of $11.19B, annual revenue of $4.27B, and an employee base of 2890. These valuation and revenue figures indicate that the company holds a significant position in the biotechnology landscape, commanding a market cap that reflects investor confidence in its pipeline and established product portfolio despite current profitability challenges.

Financial Health

The company reported revenue of $4.27B for the trailing twelve months, with a net income of $-356,148,000 and an EBITDA of $1.69B. The substantial gap between the positive revenue and negative net income reveals a cost structure where significant expenses, likely driven by research and development or restructuring costs, are eroding bottom-line profitability despite strong top-line performance. Jazz generates robust free cash flow of $1.34B, which provides the company with considerable financial flexibility to fund ongoing operations, invest in new drug candidates, or manage debt obligations without immediate need for external capital raising. The margins reflect a mixed financial picture with a gross margin of 91.7%, an operating margin of 24.6%, and a profit margin of -8.3%; the high gross margin indicates efficient production and pricing power, while the negative profit margin suggests high operating overheads are currently exceeding earnings before interest and taxes. Regarding liquidity and leverage, the firm holds $2.44B in cash against $5.43B in debt, resulting in a debt-to-equity ratio of 125.67, which characterizes a leveraged balance sheet rather than a conservative one. Short-term liquidity is supported by a current ratio of 1.86, indicating that the company possesses sufficient current assets to cover its short-term liabilities with a comfortable buffer. Return on equity stands at -8.5% while return on assets is 5.2%, revealing that while asset utilization is generating positive returns, the negative equity return indicates that shareholder equity is being diluted by net losses in the current reporting period.

Valuation Assessment

The valuation metrics show a trailing P/E ratio of N/A and a forward P/E of 7.29, implying that the market expects earnings to improve significantly in the future to justify the current price relative to anticipated profitability. The price-to-book ratio is 2.59, indicating that the market values the company at a premium of roughly 159% over its book value, likely reflecting the intangible value of its intellectual property and pipeline potential. Alternative valuation measures include a price-to-sales ratio of 2.62 and an EV/EBITDA of 8.41, which suggest the company is trading at a valuation that is sensitive to sales growth but also accounts for its high debt load and negative earnings. The stock has a 52-week high of $198.00 and a 52-week low of $95.49, meaning the current trading price sits within this wide range, though specific current pricing is not provided in the available facts to calculate an exact percentage distance from the highs. The beta value is 0.23, which signifies that the stock exhibits low price volatility relative to the broader market, moving much less than the general index and offering a more stable price profile during market fluctuations.

Growth & Income

Revenue growth stands at 10.1% year-over-year, while earnings growth is 3.2% year-over-year, indicating that earnings are growing slower than revenue, which often implies that top-line expansion is being partially offset by increased costs or amortization of intangible assets. As a non-dividend payer, the company reports a dividend yield of N/A and a payout ratio of 0.0%, meaning it does not distribute cash to shareholders and instead reinvests all earnings and cash flow back into the business to fund growth initiatives and research. This reinvestment strategy is typical for biotechnology firms in growth phases where capital allocation toward asset development is prioritized over income generation for shareholders. The overall growth and income profile presents a high-growth trajectory driven by revenue expansion but tempered by a lack of current dividend income, creating a share class suitable for investors seeking capital appreciation from a volatile but expanding pharmaceutical portfolio.

Peer Comparison

Jazz Pharmaceuticals plc (JAZZ) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Jazz Pharmaceuticals plc JAZZ $14.90B 1978.4
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Jazz Pharmaceuticals plc trades at a P/E of 1978.4.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Jazz Pharmaceuticals plc

Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally. The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idiopathic hypersomnia (IH); Epidiolex for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC); Rylaze for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma; Enrylaze to treat acute lymphoblastic leukemia and lymphoblastic lymphoma; Zepzelca for the treatment of metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy; Ziihera to treat HER2-positive biliary tract cancers; Modeyso for the treatment of diffuse midline glioma harboring an H3 K27M mutation; and Defitelio to treat severe veno-occlusive disease. It also develops Zanidatamab in Phase 3 trial to treat HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancers (BTC); Dordaviprone to treat H3 K27M-mutant diffuse glioma; and Vyxeos for the treatment of newly-diagnosed therapy-related acute myeloid leukemia. In addition, the company is developing Zanidatamab to treat neoadjuvant and adjuvant breast cancer; Vyxeos for the treatment of High-risk MDS, newly diagnosed untreated patients with high-risk AML, and De novo intermediate or adverse risk AML stratified by genomics; and JZP3507 to treat pheochromocytoma and paraganglioma that are in Phase 2 clinical trials. Further, it develops JZP815 to treat Raf and Ras mutant tumors; JZP898 for the IFN INDUKIN molecule in solid tumors; and JZP047 to treat absence epilepsy that are in Phase 1 clinical trials. The company has licensing and collaboration agreements with Redx Pharma plc, Autifony Therapeutics Limited, Zymeworks Inc., Sumitomo Pharma Co., Ltd., and Werewolf Therapeutics, Inc. Jazz Pharmaceuticals plc was founded in 2003 and is headquartered in Dublin, Ireland.

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Key Statistics

Market Cap
$14.90B
P/E Ratio
1978.42
52-Week High
$243.32
52-Week Low
$105.00
Avg Volume
894.09K
Beta
0.27

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
Ireland
Employees
2,890