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Immunocore Holdings plc (IMCR) Stock Analysis

Healthcare

Immunocore Holdings plc

$29.41

+$0.58 (+2.01%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Immunocore Holdings plc is a biotechnology entity dedicated to the development and commercialization of immunomodulating medicines designed to treat patients suffering from cancer, infectious diseases, and autoimmune conditions across the United States, Europe, and international markets. The company operates within the healthcare sector, specifically the biotechnology industry, which is characterized by high capital expenditure requirements and a focus on innovative therapeutic discovery rather than traditional manufacturing or service delivery. With a market capitalization of $1.52B, annual revenue of $400.02M, and an employee count of 524, the organization represents a mid-to-large scale player in the biopharmaceutical landscape. These valuation and revenue figures indicate that the company has achieved a significant market position and substantial operational footprint, reflecting its ability to generate meaningful top-line revenue while maintaining a substantial workforce to support its extensive pipeline of drug candidates.

Financial Health

The company reported revenue of $400.02M over the trailing twelve months, yet recorded a net income of -$35,514,000 and an EBITDA of -$22,359,000, revealing a cost structure where operating expenses significantly outpace gross profits. The wide gap between the $400.02M in revenue and the negative net income underscores the heavy investment in research and development typical of the biotechnology sector, where current earnings are often sacrificed to fund future product launches. Despite the negative net income, the company generated positive free cash flow of $23.96M, which provides essential financial flexibility to fund ongoing operations and clinical trials without immediate reliance on external equity financing. Profitability analysis shows a gross margin of 96.5%, indicating highly efficient production and sales of core products, while an operating margin of 0.0% and a profit margin of -8.9% highlight the substantial overhead costs associated with running a global biotechnology business. Liquidity analysis reveals that the company holds $864.15M in cash against $436.69M in debt, resulting in a debt-to-equity ratio of 114.61%, which suggests a leveraged balance sheet typical for growth-stage biotech firms. However, the current ratio of 4.04 indicates a robust short-term liquidity position, ensuring the company can comfortably meet its obligations with its liquid assets. Return metrics show a return on equity of -9.6% and a return on assets of -1.5%, which reveals that management is currently deploying capital to generate value for future commercialization rather than producing immediate returns, a standard characteristic for companies in the early to mid-stages of product development.

Valuation Assessment

The valuation metrics present a picture of a growth-oriented asset, with a trailing P/E ratio listed as N/A due to negative earnings and a forward P/E of -21.24, which implies that the market is pricing in significant expected earnings growth or turnaround potential rather than current profitability. The price-to-book ratio stands at 3.98, indicating that the market values the company at nearly four times its book value, suggesting a premium assigned to the intellectual property and pipeline assets that are not fully captured on the balance sheet. Alternative valuation measures include a price-to-sales ratio of 3.80 and an EV/EBITDA of -48.78, which further emphasize that traditional earnings-based multiples are less relevant, while sales-based metrics reflect the market's focus on top-line expansion and market share capture. Price action over the last year shows a 52-week high of $40.72 and a 52-week low of $23.15, with the current trading price situated somewhere within this range, reflecting market volatility and sentiment regarding the company's clinical progress. The beta of 0.82 indicates that the stock's price volatility is lower than the broader market, suggesting that Immunocore Holdings plc may be less sensitive to general market fluctuations compared to high-beta biotechnology peers.

Growth & Income

Revenue growth stands at 24.3% year-over-year, while earnings growth is N/A due to the company's current losses, implying that the company is prioritizing revenue expansion over immediate profitability. As a non-dividend payer with a dividend yield of N/A and a payout ratio of 0.0%, the company reinvests all available earnings and cash flow into research, development, and commercialization efforts rather than distributing income to shareholders. The absence of a dividend yield aligns with the biotechnology business model, where capital retention is critical for advancing clinical trials and bringing new immunomodulating medicines to market. Overall, the company's growth and income profile is defined by strong top-line expansion funded by significant cash reserves and cash flow, with no reliance on dividend income for investors.

Peer Comparison

Immunocore Holdings plc (IMCR) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Immunocore Holdings plc IMCR $1.50B N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Immunocore Holdings plc trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Immunocore Holdings plc

Immunocore Holdings plc, together with its subsidiaries, engages in the development and commercialization of immunomodulating medicines for patients with cancer, infectious diseases, and autoimmune disease in the United States, Europe, and internationally. The company offers KIMMTRAK for the treatment of unresectable or metastatic uveal melanoma. It also develops oncology programs, including tebentafusp which is in Phase 3 clinical trial for the treatment of advanced cutaneous melanoma and adjuvant uveal melanoma; brenetafusp which is in Phase 3 clinical trial for the treatment of first-line advanced cutaneous melanoma and in Phase 1/2 clinical trial for the treatment of various tumor types; IMC-R117C which is in Phase 1/2 clinical trial for the treatment of advanced solid tumors, such as colorectal cancer; and IMC-P115C which is in Phase 1 clinical trial for patients with tumors that express PRAME. In addition, the company is involved in the development of IMC-M113V which is in Phase 1 clinical trial for a potential functional cure of human immunodeficiency virus; and IMC-I109V which is in Phase 1 clinical trial for a potential functional cure of hepatitis B virus. Further, it develops IMC-S118AI which is in pre-investigation stage for the treatment of type 1 diabetes; and IMC-U120AI which is in pre-investigation stage for the treatment of atopic dermatitis. The company was founded in 1999 and is headquartered in Abingdon, the United Kingdom.

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Key Statistics

Market Cap
$1.50B
P/E Ratio
N/A
52-Week High
$40.72
52-Week Low
$27.55
Avg Volume
380.65K
Beta
0.74

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United Kingdom
Employees
524