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TSX · Biotechnology · CAD

Helix BioPharma Corp. (HBP.TO) Stock Analysis

Helix BioPharma Corp. (HBP.TO) is a Biotechnology stock listed on TSX and quoted in Canadian Dollar.

Last Updated: October 21, 2026

HBP.TO

CA$0.98

CA$0.00 (0.00%)

Oct 21, 2026 · Market close

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Price History

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HBP.TO Key Statistics

As of Oct 21, 2026
Trading
Open
CA$0.91
Previous Close
CA$0.98
Day's Range
0.90–0.98
52-Week Range
0.85–2.60
Volume
9.50K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
−0.14
Valuation
Market Cap
CA$74.85M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.04
Financials (FY)
Revenue (FY)
CA$0.00
Net Income (FY)
−CA$9.26M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
76.38M
1-Year Return
−59.34%
Dividend and dates
Earnings Date
October 29, 2026estimated
Avg Volume
7.33K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, HBP.TO closed at CA$0.98, −59.34% over 1 year.

Helix BioPharma Corp. (HBP.TO) has a market capitalization of CA$74.85M.

In fiscal 2024, HBP.TO reported revenue of CA$0.00.

HBP.TO Stock Return by Calendar Year

Helix BioPharma Corp. (HBP.TO) 10-year return: what CA$10,000 became

1 year
CA$10,000 CA$4,066
−59.34%
5 years
CA$10,000 CA$3,843
−61.57%
10 years
CA$10,000 CA$1,233
−87.67%

If you had invested CA$10,000 in Helix BioPharma Corp. (HBP.TO) 10 years ago, at the close on October 21, 2016, it would have been worth CA$1,233 at the close on October 21, 2026: −87.67% in total, −18.89% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−58.65%
2025+166.29%
2024−15.24%
2023−4.55%
2022−26.67%
2021−40.00%
2020−62.69%
2019+152.83%
2018−43.62%
2017−38.96%
2016 (partial year)−22.22%

As of October 21, 2026.

HBP.TO Revenue and Earnings by Fiscal Year

FY ends July
Fiscal yearRevenueNet incomeNet margin
2024CA$0.00−CA$9.26M—
2023CA$0.00−CA$6.29M—
2022CA$0.00−CA$6.56M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2024CA$0.00—−CA$9.24M−CA$9.26M—
2023CA$0.00—−CA$6.33M−CA$6.29M—
2022CA$0.00—−CA$6.04M−CA$6.56M—

Annual figures as reported, in the company's reporting currency. As of July 31, 2024.

Analysis

Data-derived

Company Overview

The market values Helix BioPharma Corp. (HBP.TO) at CA$74.85M. It is classified in the Biotechnology industry, within the Healthcare sector.

The 52-week range on file runs from CA$0.85 to CA$2.60. The most recent close on file for HBP.TO is CA$0.98, dated October 21, 2026. The close was unchanged from the previous session. The latest close sits 15.29% above that 52-week low.

Financial Health

The most recent full year on file, fiscal 2024, shows revenue of CA$0.00. The same year closed with a net loss of CA$9.26M. Earnings per share on a trailing basis come to −0.04.

Across the 3 fiscal years on file, revenue moves from CA$0.00 in 2022 to CA$0.00 in 2024. Of those 3 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative.

Over the trailing twelve months the total return is −59.34%. Across 10 years the annualized return works out at −18.89%. Beta against the wider market is reported at −0.14. Daily returns over the trailing 10 years annualize to a volatility of 91.41%.

Growth & Income

The record shows no dividend for HBP.TO.

The strongest complete calendar year on file is 2025 at +166.29%; the weakest is 2020 at −62.69%. Of the 9 complete calendar years on file, 2 finished higher. So far in 2026 the total return is −58.65%.

Peer Comparison

Helix BioPharma Corp. (HBP.TO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Helix BioPharma Corp. HBP.TO CA$74.85M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

Market caps are shown in each company's own trading currency, without conversion, and the peers are listed in order of these unconverted figures.

The Biotechnology industry average P/E ratio is 16.6x. Helix BioPharma Corp. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Helix BioPharma Corp.

Helix BioPharma Corp. a clinical-stage biopharmaceutical company developing therapies in the field of immune-oncology in Canada. Its product pipeline comprises L-DOS47, a clinical-stage antibody-enzyme conjugate (AEC) that neutralizes the microenvironment of solid tumors; LDOS001, which is in phase I clinical trial to treat non-small cell lung cancer; LDOS002, which is in phase I/II clinical trial for the treatment of non-small cell lung cancer; LDOS003, which is in phase II clinical trial to treat non-small cell lung cancer; LDOS006, which is in phase Ib/II for the treatment of pancreatic cancer; and LDOS007, which is in phase Ib/II for the treatment of lung cancer. It develops V-DOS47, an antibody-DOS47 conjugate that targets the vascular endothelial growth factor 2 receptor. It has collaboration agreements with Moffitt Cancer Center to investigate the pharmacodynamics of L-DOS47 and determine the benefits of combining L-DOS47 with immune checkpoint inhibitors; and with University Hospital Tuebingen to assess the therapeutic response of L-DOS47 in cancer models expressing CEACAM6, with advanced preclinical metabolic imaging. The company has an agreement with metaShape Pharma AG for covering LEUMUNA, within the field of adipose tissue-related and metabolic diseases. Helix BioPharma Corp. was incorporated in 2008 and is headquartered in Vancouver, Canada.

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