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Coya Therapeutics, Inc. (COYA) Stock Analysis

Healthcare

Coya Therapeutics, Inc.

$4.71

$-0.10 (-2.08%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Coya Therapeutics, Inc. operates as a clinical-stage biotechnology company dedicated to the development of proprietary therapies designed to enhance the function of regulatory T cells, known as Tregs, through modalities such as Treg-enhancing biologics and Treg-derived exosomes. This organization functions within the broader Healthcare sector, specifically targeting the Biotechnology industry where innovation in cellular therapies is a primary driver of research and development. The company's current scale is defined by a market capitalization of $92.89M and an annual revenue of $7.95M over the trailing twelve months, supported by a workforce of 8 employees. These valuation and revenue figures indicate that Coya is a small-cap entity with a relatively narrow revenue base that relies heavily on future clinical milestones rather than established commercial sales to drive its market position.

Financial Health

The company reports revenue of $7.95M for the trailing twelve months, yet this top-line figure contrasts sharply with a net income of -$21,226,108, revealing a cost structure where operating expenses significantly exceed revenue generation. EBITDA stands at -$20,238,262, further highlighting the substantial cash burn required to advance its clinical-stage pipeline without current commercial profitability. Free cash flow is reported at -$4,613,089, indicating that the company is consuming cash reserves to fund operations and research rather than generating liquidity from its current business activities. All three margin metrics reflect this early-stage financial reality, with a gross margin of -110.6%, an operating margin of -107.5%, and a profit margin of -267.1%, each demonstrating that costs are currently well in excess of revenue on a percentage basis. The balance sheet shows $46.82M in cash against N/A for debt, resulting in a debt-to-equity ratio of N/A, which suggests a conservative capital structure reliant on equity financing rather than leverage. A current ratio of 8.51 indicates robust short-term liquidity, as the company holds significantly more current assets than current liabilities, providing ample buffer for near-term operational needs. Return on Equity stands at -51.4% and Return on Assets is -26.9%, metrics that reveal the company is currently diluting shareholder value and utilizing assets to generate losses typical of pre-revenue biotechnology firms.

Valuation Assessment

Valuation multiples for the company reflect its lack of earnings, with a P/E Ratio (TTM) of N/A and a Forward P/E of -3.43, implying that the market is pricing the stock based on future expectations of earnings recovery rather than current profitability. The price-to-book ratio is 1.93, indicating that the market values the company at nearly double its book value, which may reflect potential in its intellectual property and clinical pipeline despite current financial losses. Alternative valuation metrics include a price-to-sales ratio of 11.69 and an EV/EBITDA of -2.28, suggesting the market places a premium on the company's revenue potential and asset base relative to its tangible book value and earnings history. The stock's recent price volatility is bounded by a 52-week high of $7.75 and a 52-week low of $3.91, meaning the current trading price sits within this established range. The beta value of 0.23 indicates that the stock exhibits low volatility relative to the broader market, moving with significantly less intensity than the overall equity index.

Growth & Income

Revenue growth over the year-over-year period is reported at 202768.8%, a figure that results from the transition from negligible prior revenue to the current $7.95M, while earnings growth is N/A due to the absence of prior-period net income data. Since the company does not pay dividends, evidenced by a dividend yield of N/A and a payout ratio of 0.0%, it does not distribute cash to shareholders but instead reinvests all available earnings into research and development efforts. The overall growth and income profile is characterized by exceptional top-line expansion percentages that mask underlying profitability challenges, with no income distribution to compensate investors for the high risk and negative returns associated with the clinical-stage development phase.

Peer Comparison

Coya Therapeutics, Inc. (COYA) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Coya Therapeutics, Inc. COYA $110.48M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Coya Therapeutics, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Coya Therapeutics, Inc.

Coya Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of proprietary therapies to enhance the function of regulatory T cells (Tregs). Its candidate product pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. The company develops COYA 302, a biologic combination for subcutaneous administration intended to enhance Treg function while depleting T effector function and activated macrophages in Phase 2 trial for use in the treatment of amyotrophic lateral sclerosis, as well as frontotemporal dementia, Alzheimer's disease (AD), and Parkinson's disease. In addition, its pre-clinical product candidates include COYA 301, a low-dose interleukin 2 product candidate to treat AD; COYA 303, an investigational biologic combination of COYA 301 and a glucagon-like-peptide-1 receptor agonist for the treatment of inflammatory diseases; COYA 201, an antigen directed Treg-derived exosome product candidate to treat neurodegenerative, autoimmune, and metabolic diseases; COYA 206, an antigen directed Treg-derived exosome product candidate; and COYA 101. It has a collaboration with Dr. Reddy's Laboratories SA for the development and commercialization of COYA 302, an investigational combination therapy for treatment of amyotrophic lateral sclerosis. Coya Therapeutics, Inc. was founded in 2020 and is headquartered in Houston, Texas.

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Key Statistics

Market Cap
$110.48M
P/E Ratio
N/A
52-Week High
$7.75
52-Week Low
$3.71
Avg Volume
154.03K

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
8