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NASDAQ · Biotechnology · USD

Cardio Diagnostics Holdings, Inc. (CDIO) Stock Analysis

Cardio Diagnostics Holdings, Inc. (CDIO) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

CDIO

$1.77

+$0.05 (+2.91%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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CDIO Key Statistics

As of Oct 21, 2026
Trading
Open
$1.81
Previous Close
$1.72
Day's Range
1.71–1.84
52-Week Range
0.97–7.91
Volume
29.26K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.24
Valuation
Market Cap
$5.18M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
358.41
EPS (ttm)Profit attributable to each share over the last twelve months.
−2.91
Financials (FY)
Revenue (FY)
$14.83K−57.51%
Net Income (FY)
−$6.50M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
2.96M
1-Year Return
−59.26%
Dividend and dates
Earnings Date
November 6, 2026estimated
Avg Volume
56.62K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, CDIO closed at $1.77, −59.26% over 1 year.

Cardio Diagnostics Holdings, Inc. (CDIO) has a market capitalization of $5.18M.

In fiscal 2025, CDIO reported revenue of $14.83K.

CDIO Stock Return by Calendar Year

Cardio Diagnostics Holdings, Inc. (CDIO) return since Jan 2022: what $10,000 became

1 year
$10,000 $4,074
−59.26%
3 years
$10,000 $2,296
−77.04%
Since Jan 2022
$10,000 $60
−99.40%

If you had invested $10,000 in Cardio Diagnostics Holdings, Inc. (CDIO) at the close on January 14, 2022, the earliest close on record here, it would have been worth $60 at the close on October 21, 2026: −99.40% in total, −65.80% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−34.69%
2025−90.15%
2024−63.17%
2023+134.91%
2022−89.21%

As of October 21, 2026.

CDIO Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$14.83K−$6.50M−43,832.5%
2024$34.89K−$8.38M−24,028.2%
2023$17.07K−$8.38M−49,087.8%
2022$950.00−$4.66M−490,630.0%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$14.83K—−$6.48M−$6.50M−43,832.5%
2024$34.89K—−$8.37M−$8.38M−24,028.2%
2023$17.07K—−$7.24M−$8.38M−49,087.8%
2022$950.00—−$4.55M−$4.66M−490,630.0%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

CDIO Valuation vs Biotechnology Median

Median of 608 stocks
MetricCDIOBiotechnology medianvs median
P/S ratio358.4113.3027.0x the median

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Cardio Diagnostics Holdings, Inc. (CDIO) carries a market capitalisation of $5.18M. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 15 employees.

The 52-week range on file runs from $0.97 to $7.91. CDIO last closed at $1.77 on October 21, 2026. That is +$0.05 (+2.91%) against the previous close. The latest close sits 82.47% above that 52-week low.

Financial Health

In fiscal 2025, Cardio Diagnostics Holdings, Inc. reported revenue of $14.83K. That is −57.51% against the prior fiscal year, when revenue was $34.89K. The same year closed with a net loss of $6.50M. Earnings per share on a trailing basis come to −2.91.

Across the 4 fiscal years on file, revenue moves from $950.00 in 2022 to $14.83K in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative. The price-to-sales ratio is 358.41. On price-to-sales that is 27 times the Biotechnology median of 13.3. The medians here are taken across 608 Biotechnology companies that report the metric.

Beta against the wider market is reported at 2.24. Annualized volatility over the trailing 4 years is 197.46%. The trailing one-year total return is −59.26%. Measured over 3 years, that is −38.77% a year compounded.

Growth & Income

No dividend is on file for CDIO.

2026 is still running; the total return is −34.69% year to date. The strongest complete calendar year on file is 2023 at +134.91%; the weakest is 2025 at −90.15%. Of the 4 complete calendar years on file, 1 finished higher.

Peer Comparison

Cardio Diagnostics Holdings, Inc. (CDIO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Cardio Diagnostics Holdings, Inc. CDIO $5.18M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Cardio Diagnostics Holdings, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Cardio Diagnostics Holdings, Inc.

Cardio Diagnostics Holdings, Inc. develops and commercializes epigenetics-based clinical tests for cardiovascular disease. The company offers Epi+Gen CHD, a three-year symptomatic coronary heart disease (CHD) risk assessment clinical blood test targeting CHD events, including heart attacks; PrecisionCHD, an integrated epigenetic-genetic clinical blood test for the detection of coronary heart disease; and Actionable Clinical Intelligence, a platform that offers new epigenetic and genetic insights to clinicians prescribing to help improve chronic care management. It also provides CardioInnovate360, a research-use-only solution to support the discovery, development and validation of novel biopharmaceuticals for the assessment and management of cardiovascular diseases; and HeartRisk, a SaaS cardiovascular disease risk intelligence platform. It serves telemedicine providers; provider organizations, such as concierge practices, longevity clinics, and risk-bearing provider organizations; and employer organizations. Cardio Diagnostics Holdings, Inc. was founded in 2017 and is headquartered in Chicago, Illinois.

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