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NASDAQ · Biotechnology · USD

Crescent Biopharma, Inc. (CBIO) Stock Analysis

Crescent Biopharma, Inc. (CBIO) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

CBIO

$13.17

+$0.10 (+0.77%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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CBIO Key Statistics

As of Oct 21, 2026
Trading
Open
$13.16
Previous Close
$13.07
Day's Range
13.12–13.81
52-Week Range
8.72–27.41
Volume
250.36K
Valuation
Market Cap
$467.31M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
39.33
EPS (ttm)Profit attributable to each share over the last twelve months.
−7.63
Financials (FY)
Revenue (FY)
$10.84M
Net Income (FY)
−$153.94M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
37.14M
1-Year Return
+4.11%
Dividend and dates
Avg Volume
402.25K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, CBIO closed at $13.17, +4.11% over 1 year.

Crescent Biopharma, Inc. (CBIO) has a market capitalization of $467.31M.

CBIO Stock Return by Calendar Year

Crescent Biopharma, Inc. (CBIO) return since Sep 2022: what $10,000 became

1 year
$10,000 $10,411
+4.11%
3 years
$10,000 $1,045
−89.55%
Since Sep 2022
$10,000 $2,245
−77.55%

If you had invested $10,000 in Crescent Biopharma, Inc. (CBIO) at the close on September 21, 2022, the earliest close on record here, it would have been worth $2,245 at the close on October 21, 2026: −77.55% in total, −30.65% a year, with dividends reinvested, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+11.05%
2025−52.56%
2024−89.41%
2023−15.03%
2022 (partial year)+373.44%

As of October 21, 2026.

CBIO Dividend History

$24.00−83.2% vs 2022

Dividends per share, 2023 · 1 payments

YearDividends per sharePaymentsChange
2023$24.001−83.2%
2022$143.001—

Most recent payment: $24.00 per share, ex-dividend January 13, 2023. Per-share amounts summed by calendar year from ex-dividend dates. Partial years are shown muted and marked with an asterisk.

CBIO Valuation vs Biotechnology Median

Median of 608 stocks
MetricCBIOBiotechnology medianvs median
P/S ratio39.3313.30196% above

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 12 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Crescent Biopharma, Inc. (CBIO) is capitalised at $467.31M on the latest close. The company sits in the Healthcare sector, in the Biotechnology industry. The company reports 69 employees.

The 52-week range on file runs from $8.72 to $27.41. The most recent close on file for CBIO is $13.17, dated October 21, 2026. That is +$0.10 (+0.77%) against the previous close. The latest close sits 51.03% above that 52-week low.

Financial Health

In fiscal 2025, Crescent Biopharma, Inc. reported revenue of $10.84M. The same year closed with a net loss of $153.94M. Trailing earnings per share are −7.63.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. The price-to-sales ratio is 39.33. On price-to-sales that is 195.71% above the Biotechnology median of 13.3. 608 Biotechnology companies report these metrics, and the medians quoted come from that group.

The trailing one-year total return is +4.11%. Across 3 years the annualized return works out at −52.89%. Annualized volatility over the trailing 4 years is 138.83%.

Growth & Income

The latest dividend on file for CBIO dates from 2023. Dividends are recorded for 2 calendar years; 2023 shows 1 payments totalling $24.00 a share. The year before, 2022, totalled $143.00 a share.

Across the complete calendar years on file, 2023 returned −15.03% and 2024 returned −89.41%. Of the 3 complete calendar years on file, 0 finished higher. 2026 is still running; the total return is +11.05% year to date.

Peer Comparison

Crescent Biopharma, Inc. (CBIO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Crescent Biopharma, Inc. CBIO $467.31M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Crescent Biopharma, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Crescent Biopharma, Inc.

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.

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