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Arvinas, Inc. (ARVN) Stock Analysis

Healthcare

Arvinas, Inc.

$8.92

$-0.17 (-1.87%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Arvinas, Inc. operates as a clinical-stage biotechnology entity dedicated to the discovery, development, and commercialization of therapies designed to degrade disease-causing proteins. The company specializes in creating proteolysis targeting chimeras, or PROTACs, which function as targeted protein degraders leveraging the body's own cellular machinery to remove specific proteins associated with pathology. Arvinas functions within the healthcare sector, specifically the biotechnology industry, an environment characterized by high research expenditures and long development cycles before products reach the market. The company currently holds a market capitalization of $660.87M and reported annual revenue of $262.60M over the trailing twelve months, employing a workforce of 246 individuals. These financial figures indicate that while the company maintains a significant market presence relative to its employee base, the revenue figure represents a substantial portion of its enterprise value, suggesting a capital-intensive operation typical of biotechnology firms where revenue recognition often precedes commercial scale-up.

Financial Health

The company reported revenue of $262.60M for the trailing twelve months, accompanied by a net income of -$80,800,000 and an EBITDA of -$111,900,000. The significant gap between positive revenue and substantial negative net income reveals a cost structure where operating expenses, including research and development and general administrative costs, far exceed the gross revenue generated, resulting in a net loss. Free cash flow stands at -$89,012,496, which indicates that the company is consuming cash to fund its operations and growth initiatives, thereby limiting immediate financial flexibility without external capital injections. Despite the negative earnings, the gross margin is listed at 100.0%, suggesting that the cost of goods sold is negligible relative to revenue, a common characteristic of early-stage biotechnology companies selling therapies or intellectual property. However, the operating margin is -754.7% and the profit margin is -30.8%, figures that highlight the heavy burden of overhead costs required to advance clinical-stage assets. The company holds $685.40M in cash against $8.90M in debt, a disparity that underscores a highly conservative balance sheet with minimal leverage. The debt-to-equity ratio of 2.05, combined with the massive cash reserve, suggests the entity is well-positioned to weather the cash burn associated with clinical trials. Liquidity is further supported by a current ratio of 4.92, indicating that current assets are nearly five times current liabilities, providing a robust buffer against short-term obligations. Return on Equity is -16.2% and Return on Assets is -7.9%, metrics that reveal the company is currently destroying value in traditional terms as it invests heavily in future potential rather than generating immediate returns for shareholders or asset holders.

Valuation Assessment

The trailing P/E ratio is N/A due to negative earnings, while the forward P/E is listed at -2.92, a negative figure that implies the market is pricing in continued losses or is utilizing a non-standard multiple for a pre-profit biotechnology stock. The price-to-book ratio is 1.51, indicating that the market values the company at one and a half times its net asset value, which may reflect intangible assets like intellectual property that are not fully captured on the balance sheet. The price-to-sales ratio is 2.52, and the EV/EBITDA is 0.16; these alternative valuation metrics suggest the market is assigning a premium to the company's revenue stream despite the lack of profitability, likely betting on the successful commercialization of its protein degradation therapies. The stock has traded between a 52-week high of $14.51 and a 52-week low of $5.90. Without a specific current share price provided in the facts, the valuation context is defined by this wide trading range, which suggests significant volatility and a wide dispersion of investor sentiment regarding the company's clinical pipeline. The beta is 1.94, a value that indicates the stock is expected to be nearly twice as volatile as the broader market, reflecting the high risk and uncertainty inherent in clinical-stage biotechnology investments.

Growth & Income

Revenue growth year-over-year is -84.0%, while earnings growth year-over-year is N/A. The negative revenue growth rate combined with the absence of positive earnings growth implies that the company is experiencing a contraction in its top line, which is common in the biotech sector during transitions between clinical phases or as prior revenue streams mature without immediate replacement. Since the company does not pay dividends, as evidenced by a dividend yield of N/A and a payout ratio of 0.0%, it reinvests all available earnings and cash reserves into research and development rather than distributing income to shareholders. This strategy of zero dividends and negative earnings growth highlights a capital allocation approach focused exclusively on advancing the clinical pipeline and achieving profitability in the future. The overall growth and income profile is characterized by significant revenue contraction and a complete absence of dividend income, positioning the company as a pure-play speculative asset dependent on future clinical success rather than current financial performance.

Peer Comparison

Arvinas, Inc. (ARVN) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Arvinas, Inc. ARVN $575.53M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Arvinas, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Arvinas, Inc.

Arvinas, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. The company develops proteolysis targeting chimeras (PROTAC) targeted protein degraders that are designed to harness the body's own natural protein disposal system to degrade and remove disease-causing proteins. It is also developing clinical development programs , including ARV-102, a leucine-rich repeat kinase 2 (LRRK2) protein for the treatment of neurodegenerative diseases, such as Parkinson's disease and progressive supranuclear palsy; ARV-806, a Kirsten rat sarcoma, G12D protein for the treatment of cancers with the G12D mutation, comprising pancreatic, colorectal, and non-small cell lung cancer; ARV-393, a B-cell lymphoma 6 protein for the treatment of relapsed/refractory non-Hodgkin lymphoma (NHL); ARV-027, a polyglutamine-expanded androgen receptor in skeletal muscle; and vepdegestrant, an estrogen receptor for the treatment of locally advanced or metastatic ER+/HER2- breast cancer. In addition, the company develops Bavdegalutamide (ARV-110) and Luxdegalutamide (ARV-766), investigational orally bioavailable PROTAC protein degraders for the treatment of men with metastatic castration-resistant prostate cancer. It has collaborations with Pfizer Inc., Genentech, Inc., F. Hoffman-La Roche Ltd., Carrick Therapeutics Limited, and Bayer AG. The company was founded in 2013 and is based in New Haven, Connecticut.

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Key Statistics

Market Cap
$575.53M
P/E Ratio
N/A
52-Week High
$14.51
52-Week Low
$6.06
Avg Volume
894.59K
Beta
1.80

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
246