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NASDAQ · Biotechnology · USD

Arcturus Therapeutics Holdings Inc. (ARCT) Stock Analysis

Arcturus Therapeutics Holdings Inc. (ARCT) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

ARCT

$11.07

+$0.09 (+0.82%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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ARCT Key Statistics

As of Oct 21, 2026
Trading
Open
$11.11
Previous Close
$10.98
Day's Range
11.05–11.34
52-Week Range
5.50–17.96
Volume
341.78K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.48
Valuation
Market Cap
$314.64M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
10.71
EPS (ttm)Profit attributable to each share over the last twelve months.
−3.33
Financials (FY)
Revenue (FY)
$67.22M−51.43%
Net Income (FY)
−$65.78M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
28.42M
1-Year Return
−52.20%
Dividend and dates
Earnings Date
November 9, 2026
Avg Volume
947.00K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, ARCT closed at $11.07, −52.20% over 1 year.

Arcturus Therapeutics Holdings Inc. (ARCT) has a market capitalization of $314.64M.

In fiscal 2025, ARCT reported revenue of $67.22M.

ARCT Stock Return by Calendar Year

Arcturus Therapeutics Holdings Inc. (ARCT) 10-year return: what $10,000 became

1 year
$10,000 $4,780
−52.20%
5 years
$10,000 $2,484
−75.16%
10 years
$10,000 $6,846
−31.54%

If you had invested $10,000 in Arcturus Therapeutics Holdings Inc. (ARCT) 10 years ago, at the close on October 21, 2016, it would have been worth $6,846 at the close on October 21, 2026: −31.54% in total, −3.72% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+80.59%
2025−63.88%
2024−46.18%
2023+85.91%
2022−54.17%
2021−14.68%
2020+299.08%
2019+139.96%
2018−43.02%
2017−45.92%
2016 (partial year)−55.79%

As of October 21, 2026.

ARCT Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$67.22M−$65.78M−97.9%
2024$138.39M−$80.94M−58.5%
2023$157.75M−$29.73M−18.8%
2022$205.76M$9.35M4.5%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$67.22M—−$76.26M−$65.78M−97.9%
2024$138.39M—−$95.67M−$80.94M−58.5%
2023$157.75M—−$78.21M−$29.73M−18.8%
2022$205.76M—$12.18M$9.35M4.5%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

ARCT Valuation vs Biotechnology Median

Median of 608 stocks
MetricARCTBiotechnology medianvs median
P/S ratio10.7113.3019% below

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 19 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Arcturus Therapeutics Holdings Inc. (ARCT) carries a market capitalisation of $314.64M. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 106.

ARCT last closed at $11.07 on October 21, 2026. That is +$0.09 (+0.82%) against the previous close. Over the past 52 weeks the price has ranged from $5.50 to $17.96. The latest close sits 101.27% above that 52-week low.

Financial Health

In fiscal 2025, Arcturus Therapeutics Holdings Inc. reported revenue of $67.22M. Against the prior fiscal year total of $138.39M, that is a change of −51.43%. The same year closed with a net loss of $65.78M. Trailing earnings per share are −3.33.

Across the 4 fiscal years on file, revenue moves from $205.76M in 2022 to $67.22M in 2025. Of those 4 years, 1 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative. The price-to-sales ratio is 10.71. On price-to-sales that is 19.44% below the Biotechnology median of 13.3. The medians here are taken across 608 Biotechnology companies that report the metric.

The reported beta is 2.48. Annualized volatility over the trailing 10 years is 96.28%. The trailing one-year total return is −52.20%. Across 10 years the annualized return works out at −3.72%.

Growth & Income

No dividend is on file for ARCT.

So far in 2026 the total return is +80.59%. The strongest complete calendar year on file is 2020 at +299.08%; the weakest is 2025 at −63.88%. Of the 9 complete calendar years on file, 3 finished higher.

Peer Comparison

Arcturus Therapeutics Holdings Inc. (ARCT) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Arcturus Therapeutics Holdings Inc. ARCT $314.64M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Arcturus Therapeutics Holdings Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Arcturus Therapeutics Holdings Inc.

Arcturus Therapeutics Holdings Inc., a messenger RNA medicines company, focuses on the development of liver and respiratory rare disease therapeutics. Its technology platforms include STARR, a self-amplifying mRNA technology platform, and LUNAR, a lipid-mediated delivery system. The company also develops ARCT-032 (LUNAR-CF), an mRNA therapeutic candidate for cystic fibrosis that is in Phase 2 clinical development; and ARCT-810 (LUNAR-OTC), which is in Phase 2 clinical development to address ornithine transcarbamylase (OTC) deficiency. In addition, it develops KOSTAIVE, a self-amplifying RNA vaccine for COVID-19; ARCT-2138 (LUNAR-FLU), which is in Phase1 clinical trial for the treatment of seasonal influenza; and ARCT-2304 (LUNAR-H5N1) that is in Phase1 clinical trial for the treatment of Pandemic Influenza. Arcturus Therapeutics Holdings Inc. was founded in 2013 and is headquartered in San Diego, California.

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