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NYSE · Biotechnology · USD

Alto Neuroscience, Inc. (ANRO) Stock Analysis

Alto Neuroscience, Inc. (ANRO) is a Biotechnology stock listed on NYSE and quoted in US Dollar.

ANRO

$35.55

−$0.85 (−2.34%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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ANRO Key Statistics

As of Sep 4, 2026
Trading
Open
$36.18
Previous Close
$36.40
Day's Range
35.45–36.98
52-Week Range
3.50–37.48
Volume
269.90K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.16
Valuation
Market Cap
$1.40B
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−2.26
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$63.24M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
39.24M
1-Year Return
+912.82%
Dividend and dates
Earnings Date
November 11, 2026estimated
Avg Volume
546.47K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

ANRO Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+99.72%
2025+320.80%
2024 (partial year)−79.57%

As of September 4, 2026.

ANRO Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$63.24M
2024$0.00−$61.43M
2023$0.00−$36.31M
2022$0.00−$27.71M
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00−$66.36M−$63.24M
2024$0.00−$68.61M−$61.43M
2023$0.00−$37.81M−$36.31M
2022$0.00−$27.46M−$27.71M

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

ANRO Valuation vs Biotechnology Median

Median of 656 stocks
MetricANROBiotechnology medianvs median
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

All 10 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Alto Neuroscience, Inc. (ANRO) at $1.40B. The company sits in the Healthcare sector, in the Biotechnology industry. Headcount on file is 68.

The most recent close on file for ANRO is $35.55, dated September 4, 2026. That is −$0.85 (−2.34%) against the previous close. The 52-week range on file runs from $3.50 to $37.48. The latest close sits 915.71% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $63.24M. Profit margin runs at 0%. Earnings per share on a trailing basis come to −2.26.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Over the trailing twelve months the price has returned +912.82%. The stored price history starts on February 2, 2024, and the total return since then is +71.74%. The reported beta is 1.16. Annualized volatility over the trailing 2 years is 118.07%.

Growth & Income

No dividend is on file for ANRO.

2026 is still running; the price is +99.72% year to date. The record holds one complete calendar year, 2025, which returned +320.80%.

Peer Comparison

Alto Neuroscience, Inc. (ANRO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Alto Neuroscience, Inc. ANRO $1.40B
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. Alto Neuroscience, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Alto Neuroscience, Inc.

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company's product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson's disease for patients with Parkinson's disease. The company was incorporated in 2019 and is headquartered in Mountain View, California.

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