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Shattuck Labs, Inc. (STTK) Stock Analysis

Healthcare

Shattuck Labs, Inc.

$6.11

+$0.01 (+0.16%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Shattuck Labs, Inc. operates as a clinical-stage biotechnology entity focused on the development of antibodies designed to treat inflammatory and immune-mediated diseases within the United States market. The company specifically concentrates its research and development efforts on SL-325, a death receptor 3 blocking monoclonal antibody that is currently advancing through Phase I clinical trials. This business falls under the Healthcare sector and the Biotechnology industry, positioning the firm to leverage significant research and development capabilities while navigating a highly regulated environment for drug approval. The company maintains a market capitalization of $455.86M and employs a workforce of 40 individuals, reflecting a lean operational structure typical of early-stage biotech firms. These financial figures indicate that the company is a micro-cap entity with substantial market value relative to its reported revenue of $1.00M, suggesting that its valuation is driven primarily by the potential future value of its pipeline rather than current cash flows or earnings performance.

Financial Health

The company reported a trailing twelve-month revenue of $1.00M alongside a net income of $-48,809,000 and an EBITDA of $-47,739,000. The substantial gap between the minimal revenue and the large negative net income reveals a cost structure characterized by heavy expenditures on research, development, and clinical trial activities that far exceed current sales. Shattuck Labs, Inc. generated free cash flow of $-21,513,876, which indicates that the company is currently consuming cash reserves to fund its operations and is not yet generating positive cash flow from its business activities. Gross margin stands at -195.1%, operating margin at -5142.7%, and profit margin at 0.0%, highlighting extreme negative profitability typical of clinical-stage biotechs where expenses are incurred before product revenue is realized. The firm holds cash totaling $78.06M against a debt load of $2.42M, resulting in a debt-to-equity ratio of 2.94, which suggests a balance sheet that is leveraged but maintains significant liquidity buffers despite the negative equity position implied by returns. The current ratio is 11.70, indicating an exceptionally strong short-term liquidity position where current assets are more than eleven times current liabilities. Return on equity is -60.3% and return on assets is -35.3%, metrics that reveal management is currently diluting shareholder value and utilizing assets to generate losses as part of the standard development phase for a clinical-stage biotechnology company.

Valuation Assessment

The trailing P/E ratio is N/A due to the absence of positive earnings, while the forward P/E is -13.34, implying that the market is pricing the stock based on future expectations of earnings recovery or continued losses rather than current profitability. The price-to-book ratio is 4.89, indicating that the market values the company at nearly five times its book value, which suggests a significant premium assigned to the intangible assets of the clinical pipeline and future revenue potential. Alternative valuation metrics such as the price-to-sales ratio of 455.86 and an EV/EBITDA of -7.96 suggest that investors are placing a high multiple on the company's sales and enterprise value relative to its negative earnings, reflecting the speculative nature of investing in pre-commercial assets. The stock has traded between a 52-week low of $0.69 and a 52-week high of $6.59, with the current market capitalization of $455.86M implying a valuation that sits in the upper range of this historical volatility band relative to its smallest price point. The beta is 1.67, which indicates that the stock price is expected to be 67% more volatile than the broader market, exposing investors to significantly higher fluctuations in share price compared to large-cap healthcare peers.

Growth & Income

Shattuck Labs, Inc. reports N/A for revenue growth year-over-year and N/A for earnings growth year-over-year, reflecting the early stage of the company where historical growth rates are not yet established or meaningful due to the lack of a commercial product portfolio. Since the company does not pay a dividend, the dividend yield is N/A and the payout ratio is 0.0%, indicating that the firm retains all of its earnings and cash reserves to reinvest into its drug development programs rather than distributing income to shareholders. The absence of a dividend payout aligns with the company's lifecycle stage, where capital allocation is directed toward advancing SL-325 through clinical trials rather than returning capital to investors. The overall growth and income profile is defined by high volatility and a complete absence of current income generation, relying entirely on the successful progression of its clinical assets to unlock future value.

Peer Comparison

Shattuck Labs, Inc. (STTK) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Shattuck Labs, Inc. STTK $468.52M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Shattuck Labs, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Shattuck Labs, Inc.

Shattuck Labs, Inc., a clinical-stage biotechnology company, engages in the development of antibodies for the treatment of inflammatory and immune-mediated diseases in the United States. The company develops SL-325, a death receptor 3 blocking monoclonal antibody, which is in Phase I clinical trial for the treatment of tumor necrosis factor like ligand 1A; and SL-425, a half-life extended version of SL-325, which is under IND-enabling chronic good laboratory practices toxicity study. It is also involved in the development of various preclinical DR3-based bispecific antibodies for the treatment of patients with inflammatory bowel disease or other immune-mediated indications; and TRIM7, an oncology-focused program. The company was incorporated in 2016 and is headquartered in Austin, Texas.

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Key Statistics

Market Cap
$468.52M
P/E Ratio
N/A
52-Week High
$8.33
52-Week Low
$0.71
Avg Volume
614.40K
Beta
1.19

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
40