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NASDAQ · Biotechnology · USD

Shattuck Labs, Inc. (STTK) Stock Analysis

Shattuck Labs, Inc. (STTK) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

STTK

$5.58

−$0.26 (−4.45%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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STTK Key Statistics

As of Oct 21, 2026
Trading
Open
$5.85
Previous Close
$5.84
Day's Range
5.57–6.00
52-Week Range
1.72–8.33
Volume
1.20M
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.10
Valuation
Market Cap
$560.03M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
560.03
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.47
Financials (FY)
Revenue (FY)
$1.00M−82.52%
Net Income (FY)
−$48.81M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
100.36M
1-Year Return
+190.63%
Dividend and dates
Earnings Date
November 12, 2026estimated
Avg Volume
1.14M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, STTK closed at $5.58, +190.63% over 1 year.

Shattuck Labs, Inc. (STTK) has a market capitalization of $560.03M.

In fiscal 2025, STTK reported revenue of $1.00M.

STTK Stock Return by Calendar Year

Shattuck Labs, Inc. (STTK) return since Oct 2020: what $10,000 became

1 year
$10,000 $29,063
+190.63%
5 years
$10,000 $2,894
−71.06%
Since Oct 2020
$10,000 $2,884
−71.16%

If you had invested $10,000 in Shattuck Labs, Inc. (STTK) at the close on October 9, 2020, the earliest close on record here, it would have been worth $2,884 at the close on October 21, 2026: −71.16% in total, −18.63% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+52.88%
2025+201.65%
2024−83.03%
2023+210.00%
2022−72.97%
2021−83.76%
2020 (partial year)+170.85%

As of October 21, 2026.

STTK Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$1.00M−$48.81M−4,880.9%
2024$5.72M−$75.41M−1,318.1%
2023$1.66M−$87.30M−5,268.4%
2022$652.00K−$101.95M−15,635.7%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$1.00M—−$51.51M−$48.81M−4,880.9%
2024$5.72M—−$80.57M−$75.41M−1,318.1%
2023$1.66M—−$91.96M−$87.30M−5,268.4%
2022$652.00K—−$103.33M−$101.95M−15,635.7%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

STTK Valuation vs Biotechnology Median

Median of 608 stocks
MetricSTTKBiotechnology medianvs median
P/S ratio560.0313.3042.1x the median

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 11 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Shattuck Labs, Inc. (STTK) at $560.03M. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 40.

The most recent close on file for STTK is $5.58, dated October 21, 2026. That is −$0.26 (−4.45%) against the previous close. The 52-week range on file runs from $1.72 to $8.33. The latest close sits 224.42% above that 52-week low.

Financial Health

In fiscal 2025, Shattuck Labs, Inc. reported revenue of $1.00M. Against the prior fiscal year total of $5.72M, that is a change of −82.52%. The same year closed with a net loss of $48.81M. Trailing earnings per share are −0.47.

Across the 4 fiscal years on file, revenue moves from $652.00K in 2022 to $1.00M in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative. The price-to-sales ratio is 560.03. On price-to-sales that is 42.1 times the Biotechnology median of 13.3. 608 Biotechnology companies report these metrics, and the medians quoted come from that group.

Beta against the wider market is reported at 1.1. Annualized volatility over the trailing 6 years is 112.73%. Over the trailing twelve months the total return is +190.63%. Measured over 5 years, that is −21.96% a year compounded.

Growth & Income

The record shows no dividend for STTK.

2026 is still running; the total return is +52.88% year to date. The strongest complete calendar year on file is 2023 at +210.00%; the weakest is 2021 at −83.76%. Of the 5 complete calendar years on file, 2 finished higher.

Peer Comparison

Shattuck Labs, Inc. (STTK) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Shattuck Labs, Inc. STTK $560.03M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Shattuck Labs, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Shattuck Labs, Inc.

Shattuck Labs, Inc., a clinical-stage biotechnology company, engages in the development of antibodies for the treatment of inflammatory and immune-mediated diseases in the United States. The company develops SL-325, a death receptor 3 blocking monoclonal antibody, which is in Phase I clinical trial for the treatment of tumor necrosis factor like ligand 1A; and SL-425, a half-life extended version of SL-325, which is under IND-enabling chronic good laboratory practices toxicity study. It is also involved in the development of various preclinical DR3-based bispecific antibodies for the treatment of patients with inflammatory bowel disease or other immune-mediated indications; and TRIM7, an oncology-focused program. The company was incorporated in 2016 and is headquartered in Austin, Texas.

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