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NASDAQ · Drug Manufacturers - Specialty & Generic · USD

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) Stock Analysis

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) is a Drug Manufacturers - Specialty & Generic stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

SHPH

$4.82

−$0.09 (−1.83%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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SHPH Key Statistics

As of Oct 21, 2026
Trading
Open
$4.90
Previous Close
$4.91
Day's Range
4.76–4.95
52-Week Range
2.58–44.40
Volume
6.19K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.14
Valuation
Market Cap
$22.97M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−16.87
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$11.72M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
4.76M
1-Year Return
−86.11%
Dividend and dates
Avg Volume
130.74K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, SHPH closed at $4.82, −86.11% over 1 year.

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) has a market capitalization of $22.97M.

In fiscal 2025, SHPH reported revenue of $0.00.

SHPH Stock Return by Calendar Year

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) return since Aug 2022: what $10,000 became

1 year
$10,000 $1,389
−86.11%
3 years
$10,000 $42
−99.58%
Since Aug 2022
$10,000 $0.63
−99.99%

If you had invested $10,000 in Shuttle Pharmaceuticals Holdings, Inc. (SHPH) at the close on August 31, 2022, the earliest close on record here, it would have been worth $0.63 at the close on October 21, 2026: −99.99% in total, −90.35% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−73.22%
2025−91.62%
2024−76.40%
2023−76.79%
2022 (partial year)−94.91%

As of October 21, 2026.

SHPH Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$11.72M—
2024$0.00−$9.14M—
2023$0.00−$6.59M—
2022$0.00−$5.00M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$11.92M−$11.72M—
2024$0.00—−$7.70M−$9.14M—
2023$0.00—−$5.89M−$6.59M—
2022$0.00—−$2.34M−$5.00M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) is capitalised at $22.97M on the latest close. It is classified in the Drug Manufacturers - Specialty & Generic industry, within the Healthcare sector. The company reports 2 employees.

The most recent close on file for SHPH is $4.82, dated October 21, 2026. That is −$0.09 (−1.83%) against the previous close. The 52-week range on file runs from $2.58 to $44.40. The latest close sits 87.11% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $11.72M. Trailing earnings per share are −16.87.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative.

Beta against the wider market is reported at 1.14. Annualized volatility over the trailing 4 years is 116.78%. Over the trailing twelve months the total return is −86.11%. Measured over 3 years, that is −83.92% a year compounded.

Growth & Income

No dividend is on file for SHPH.

The strongest complete calendar year on file is 2024 at −76.40%; the weakest is 2025 at −91.62%. Of the 3 complete calendar years on file, 0 finished higher. So far in 2026 the total return is −73.22%.

Peer Comparison

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) operates in the Drug Manufacturers - Specialty & Generic industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Shuttle Pharmaceuticals Holdings, Inc. SHPH $22.97M —
Takeda Pharmaceutical Company Limited TAK $63.67B —
Teva Pharmaceutical Industries Limited TEVA $47.37B 67.7
Haleon plc HLN $44.06B 20.5

The Drug Manufacturers - Specialty & Generic industry average P/E ratio is 20.3x. Shuttle Pharmaceuticals Holdings, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Shuttle Pharmaceuticals Holdings, Inc.

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to treat cancers. It owns a pharmaceutical software artificial intelligence (AI) driven platform for molecular discovery and early-stage drug development. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.

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