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NASDAQ · Drug Manufacturers - Specialty & Generic · USD

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) Stock Analysis

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) is a Drug Manufacturers - Specialty & Generic stock listed on NASDAQ and quoted in US Dollar.

SHPH

$3.50

+$0.02 (+0.57%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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SHPH Key Statistics

As of Sep 4, 2026
Trading
Open
$3.52
Previous Close
$3.48
Day's Range
3.40–3.59
52-Week Range
2.58–55.90
Volume
8.10K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.22
Valuation
Market Cap
$2.05M
P/E Ratio
35.00
EPS (ttm)Profit attributable to each share over the last twelve months.
0.10
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$11.72M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
585.13K
1-Year Return
−89.74%
Dividend and dates
Avg Volume
2.15M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

SHPH Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−80.56%
2025−91.62%
2024−76.40%
2023−76.79%
2022 (partial year)−94.91%

As of September 4, 2026.

SHPH Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$11.72M—
2024$0.00−$9.14M—
2023$0.00−$6.59M—
2022$0.00−$5.00M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$11.92M−$11.72M—
2024$0.00—−$7.70M−$9.14M—
2023$0.00—−$5.89M−$6.59M—
2022$0.00—−$2.34M−$5.00M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

SHPH Valuation vs Drug Manufacturers - Specialty & Generic Median

Median of 103 stocks
MetricSHPHDrug Manufacturers - Specialty & Generic medianvs median
P/E35.0019.2782% above
Profit margin0.00%−3.14%3.1 pts above

Medians across 103 Drug Manufacturers - Specialty & Generic stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Analysis

Data-derived

Company Overview

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) is capitalised at $2.05M on the latest close. It is classified in the Drug Manufacturers - Specialty & Generic industry, within the Healthcare sector. The company reports 2 employees.

The most recent close on file for SHPH is $3.50, dated September 4, 2026. That is +$0.02 (+0.57%) against the previous close. The 52-week range on file runs from $2.58 to $55.90. The latest close sits 35.87% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $11.72M. Profit margin runs at 0%. That is 3.1 percentage points above the Drug Manufacturers - Specialty & Generic median of −3.14%. Trailing earnings per share are 0.1.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

On trailing earnings, the shares are priced at 35 times earnings. That is 81.68% above the Drug Manufacturers - Specialty & Generic median of 19.27. The medians here are taken across 103 Drug Manufacturers - Specialty & Generic companies that report the metric.

Beta against the wider market is reported at 1.22. Annualized volatility over the trailing 4 years is 124.4%. Over the trailing twelve months the price has returned −89.74%. Measured over 3 years, that is −86.88% a year compounded.

Growth & Income

No dividend is on file for SHPH.

The strongest complete calendar year on file is 2024 at −76.40%; the weakest is 2025 at −91.62%. Of the 3 complete calendar years on file, 0 finished higher. So far in 2026 the price is −80.56%.

Peer Comparison

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) operates in the Drug Manufacturers - Specialty & Generic industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Shuttle Pharmaceuticals Holdings, Inc. SHPH $2.05M 35.0
Takeda Pharmaceutical Company Limited TAK $58.92B —
Teva Pharmaceutical Industries Limited TEVA $42.37B 60.6
Haleon plc HLN $42.22B 20.0

The Drug Manufacturers - Specialty & Generic industry average P/E ratio is 19.3x. Shuttle Pharmaceuticals Holdings, Inc. trades at a P/E of 35.0.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Shuttle Pharmaceuticals Holdings, Inc.

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to treat cancers. It owns a pharmaceutical software artificial intelligence (AI) driven platform for molecular discovery and early-stage drug development. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.

Visit website →