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NASDAQ · Medical Devices · USD

Pacific Biosciences of California, Inc. (PACB) Stock Analysis

Pacific Biosciences of California, Inc. (PACB) is a Medical Devices stock listed on NASDAQ and quoted in US Dollar.

PACB

$1.35

+$0.05 (+3.85%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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PACB Key Statistics

As of Sep 4, 2026
Trading
Open
$1.30
Previous Close
$1.30
Day's Range
1.29–1.35
52-Week Range
1.07–2.73
Volume
2.76M
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.31
Valuation
Market Cap
$419.62M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
2.63
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.42
Financials (FY)
Revenue (FY)
$160.01M+3.89%
Net Income (FY)
−$546.38M
Profit marginThe share of revenue left as profit after all costs and taxes.
−82.49%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
310.83M
1-Year Return
+8.87%
Dividend and dates
Earnings Date
November 5, 2026
Avg Volume
6.58M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

PACB Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−27.81%
2025+2.19%
2024−81.35%
2023+19.93%
2022−60.02%
2021−21.13%
2020+404.67%
2019−30.54%
2018+180.30%
2017−30.53%
2016 (partial year)−56.07%

As of September 4, 2026.

PACB Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$160.01M−$546.38M−341.5%
2024$154.01M−$309.85M−201.2%
2023$200.52M−$306.74M−153.0%
2022$128.30M−$314.25M−244.9%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$160.01M$45.78M−$557.56M−$546.38M−341.5%
2024$154.01M$37.28M−$290.66M−$309.85M−201.2%
2023$200.52M$52.78M−$310.37M−$306.74M−153.0%
2022$128.30M$49.04M−$304.82M−$314.25M−244.9%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

PACB Valuation vs Medical Devices Median

Median of 151 stocks
MetricPACBMedical Devices medianvs median
P/S ratio2.632.9811% below
Profit margin−82.49%−1.69%80.8 pts below

Medians across 151 Medical Devices stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

All 11 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Pacific Biosciences of California, Inc. (PACB) carries a market capitalisation of $419.62M. The company sits in the Healthcare sector, in the Medical Devices industry. Headcount on file is 485.

The most recent close on file for PACB is $1.35, dated September 4, 2026. That is +$0.05 (+3.85%) against the previous close. The 52-week range on file runs from $1.07 to $2.73. The latest close sits 26.17% above that 52-week low.

Financial Health

In fiscal 2025, Pacific Biosciences of California, Inc. reported revenue of $160.01M. Against the prior fiscal year total of $154.01M, that is a change of +3.89%. The same year closed with a net loss of $546.38M. Profit margin runs at −82.49%. That is 80.8 percentage points below the Medical Devices median of −1.69%. Trailing earnings per share are −0.42.

Across the 4 fiscal years on file, revenue moves from $128.30M in 2022 to $160.01M in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. The price-to-sales ratio is 2.63. On price-to-sales that is 11.47% below the Medical Devices median of 2.98. 151 Medical Devices companies report these metrics, and the medians quoted come from that group.

Over the trailing twelve months the price has returned +8.87%. Across 10 years the annualized return works out at −16.59%. Beta against the wider market is reported at 2.31. Annualized volatility over the trailing 10 years is 85.28%.

Growth & Income

The record shows no dividend for PACB.

The strongest complete calendar year on file is 2020 at +404.67%; the weakest is 2024 at −81.35%. Of the 9 complete calendar years on file, 4 finished higher. So far in 2026 the price is −27.81%.

Peer Comparison

Pacific Biosciences of California, Inc. (PACB) operates in the Medical Devices industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Pacific Biosciences of California, Inc. PACB $419.62M
Abbott Laboratories ABT $187.45B 35.1
Medtronic plc. MDT $120.46B 22.9
Stryker Corporation SYK $116.27B 31.9

The Medical Devices industry average P/E ratio is 26.8x. Pacific Biosciences of California, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About Pacific Biosciences of California, Inc.

Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems. The company provides sequencing systems; consumable products, including single molecule real-time (SMRT) technology; long-read sequencing; and various reagent kits designed for specific workflow, such as preparation kit to convert DNA into SMRTbell double-stranded DNA library formats, including molecular biology reagents, such as ligase, buffers, and exonucleases. It also offers binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing; and sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. In addition, the company provides Revio, Vega, and Sequel instruments which conduct, monitor, and analyze single-molecule biochemical reactions on SMRT cell microchips; short-read sequencing; and onso instrument. It serves academic and governmental research institutions, commercial testing and service laboratories, genome centers, public health labs, hospitals and clinical research institutes, contract research organizations, pharmaceutical companies, and agricultural companies. The company markets its products through a sales force and distribution partners in Australia, certain parts of Asia, Europe, the Middle East, Africa, Central America, and South America. It has a collaboration with DNAstack Inc. to provide federated dataset of HiFi whole genome sequencing data. The company was formerly known as Nanofluidics, Inc. and changed its name to Pacific Biosciences of California, Inc. in 2005. Pacific Biosciences of California, Inc. was incorporated in 2000 and is headquartered in Menlo Park, California.

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