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StockVS

NASDAQ · Diagnostics & Research · USD

GRAIL, Inc. (GRAL) Stock Analysis

GRAIL, Inc. (GRAL) is a Diagnostics & Research stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

GRAL

$132.60

+$7.93 (+6.36%)

Oct 21, 2026 · Market close

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Price History

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GRAL Key Statistics

As of Oct 21, 2026
Trading
Open
$123.96
Previous Close
$124.67
Day's Range
123.20–134.91
52-Week Range
41.50–166.48
Volume
599.35K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.84
Valuation
Market Cap
$5.92B
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
35.84
EPS (ttm)Profit attributable to each share over the last twelve months.
−9.70
Financials (FY)
Revenue (FY)
$147.17M+17.18%
Net Income (FY)
−$408.35M
Profit marginThe share of revenue left as profit after all costs and taxes.
−236.95%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
44.67M
1-Year Return
+58.40%
Dividend and dates
Earnings Date
November 4, 2026
Avg Volume
982.98K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, GRAL closed at $132.60, +58.40% over 1 year.

GRAIL, Inc. (GRAL) has a market capitalization of $5.92B.

In fiscal 2025, GRAL reported revenue of $147.17M.

GRAL Stock Return by Calendar Year

GRAIL, Inc. (GRAL) return since Jun 2024: what $10,000 became

1 year
$10,000 $15,840
+58.40%
Since Jun 2024
$10,000 $97,072
+870.72%

If you had invested $10,000 in GRAIL, Inc. (GRAL) at the close on June 12, 2024, the earliest close on record here, it would have been worth $97,072 at the close on October 21, 2026: +870.72% in total, +162.27% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+54.92%
2025+379.50%
2024 (partial year)+30.67%

As of October 21, 2026.

GRAL Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$147.17M−$408.35M−277.5%
2024$125.60M−$2.03B−1,613.9%
2023$93.11M−$1.47B−1,574.2%
2022$55.55M−$5.40B−9,719.3%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$147.17M−$62.57M−$534.16M−$408.35M−277.5%
2024$125.60M−$78.02M−$768.22M−$2.03B−1,613.9%
2023$93.11M−$95.61M−$796.92M−$1.47B−1,574.2%
2022$55.55M−$116.45M−$742.46M−$5.40B−9,719.3%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

GRAL Valuation vs Diagnostics & Research Median

Median of 45 stocks
MetricGRALDiagnostics & Research medianvs median
P/S ratio35.845.236.9x the median
Profit margin−236.95%−0.93%236.0 pts below

Medians across 45 Diagnostics & Research stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 20 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values GRAIL, Inc. (GRAL) at $5.92B. It is classified in the Diagnostics & Research industry, within the Healthcare sector. The company reports 910 employees.

The most recent close on file for GRAL is $132.60, dated October 21, 2026. That is +$7.93 (+6.36%) against the previous close. The 52-week range on file runs from $41.50 to $166.48. The latest close sits 219.52% above that 52-week low.

Financial Health

The most recent full year on file, fiscal 2025, shows revenue of $147.17M. That is +17.18% against the prior fiscal year, when revenue was $125.60M. The same year closed with a net loss of $408.35M. Profit margin runs at −236.95%. That is 236 percentage points below the Diagnostics & Research median of −0.93%. Earnings per share on a trailing basis come to −9.7.

Across the 4 fiscal years on file, revenue moves from $55.55M in 2022 to $147.17M in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. The price-to-sales ratio is 35.84. On price-to-sales that is 6.9 times the Diagnostics & Research median of 5.23. 45 Diagnostics & Research companies report these metrics, and the medians quoted come from that group.

The reported beta is 2.84. Annualized volatility over the trailing 2 years is 107.86%. The trailing one-year total return is +58.40%. The stored price history starts on June 12, 2024, and the total return since then is +870.72%.

Growth & Income

The record shows no dividend for GRAL.

2026 is still running; the total return is +54.92% year to date. The record holds one complete calendar year, 2025, which returned +379.50%.

Peer Comparison

GRAIL, Inc. (GRAL) operates in the Diagnostics & Research industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
GRAIL, Inc. GRAL $5.92B —
Thermo Fisher Scientific Inc. TMO $256.61B 37.4
Danaher Corporation DHR $164.40B 41.7
Natera, Inc. NTRA $59.59B —

The Diagnostics & Research industry average P/E ratio is 37.6x. GRAIL, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About GRAIL, Inc.

GRAIL, Inc., a commercial-stage healthcare company, provides multi-cancer early detection testing and services in the United States and internationally. It offers Galleri, a cancer screening test for asymptomatic individuals over 50 years of age; and a diagnostic aid for cancer tests to accelerate diagnostic resolution for patients with clinical suspicion of cancer. The company also provides development services, including support for ongoing clinical studies, pilot testing, research, and therapy development. In addition, its precision oncology portfolio consists of n RUO-targeted methylation-based platform that enables applications for disease prognostication, risk stratification, minimal residual disease detection, and recurrence and relapse monitoring. The company was incorporated in 2015 and is headquartered in Menlo Park, California.

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