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NASDAQ · Biotechnology · USD

CalciMedica, Inc. (CALC) Stock Analysis

CalciMedica, Inc. (CALC) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

CALC

$1.15

+$0.08 (+7.98%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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CALC Key Statistics

As of Oct 21, 2026
Trading
Open
$1.10
Previous Close
$1.07
Day's Range
1.07–1.20
52-Week Range
1.09–36.00
Volume
103.06K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.10
Valuation
Market Cap
$7.65M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−6.85
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$29.56M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
6.83M
1-Year Return
−92.65%
Dividend and dates
Avg Volume
75.60K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, CALC closed at $1.15, −92.65% over 1 year.

CalciMedica, Inc. (CALC) has a market capitalization of $7.65M.

In fiscal 2025, CALC reported revenue of $0.00.

CALC Stock Return by Calendar Year

CalciMedica, Inc. (CALC) return since Jun 2023: what $10,000 became

1 year
$10,000 $735
−92.65%
3 years
$10,000 $1,230
−87.70%
Since Jun 2023
$10,000 $394
−96.06%

If you had invested $10,000 in CalciMedica, Inc. (CALC) at the close on June 14, 2023, the earliest close on record here, it would have been worth $394 at the close on October 21, 2026: −96.06% in total, −61.88% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−96.51%
2025+86.16%
2024+23.78%
2023 (partial year)−51.03%

As of October 21, 2026.

CALC Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$29.56M—
2024$0.00−$13.70M—
2023$0.00−$34.36M—
2022$0.00−$7.82M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$23.12M−$29.56M—
2024$0.00—−$24.20M−$13.70M—
2023$0.00—−$38.08M−$34.36M—
2022$0.00—−$14.19M−$7.82M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

All 8 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values CalciMedica, Inc. (CALC) at $7.65M. The company sits in the Healthcare sector, in the Biotechnology industry. Headcount on file is 15.

The most recent close on file for CALC is $1.15, dated October 21, 2026. That is +$0.08 (+7.98%) against the previous close. Over the past 52 weeks the price has ranged from $1.09 to $36.00. The latest close sits 5.99% above that 52-week low.

Financial Health

In fiscal 2025, CalciMedica, Inc. reported revenue of $0.00. The same year closed with a net loss of $29.56M. Trailing earnings per share are −6.85.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

Beta against the wider market is reported at 1.1. Daily returns over the trailing 3 years annualize to a volatility of 115.91%. The trailing one-year total return is −92.65%. Across 3 years the annualized return works out at −50.27%.

Growth & Income

The record shows no dividend for CALC.

The strongest complete calendar year on file is 2025 at +86.16%; the weakest is 2024 at +23.78%. So far in 2026 the total return is −96.51%.

Peer Comparison

CalciMedica, Inc. (CALC) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
CalciMedica, Inc. CALC $7.65M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. CalciMedica, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About CalciMedica, Inc.

CalciMedica, Inc., a clinical-stage biopharmaceutical company, develops therapeutics for illnesses caused by inflammatory and immunologic processes and direct cellular damage. Its lead product candidate comprises Auxora, an intravenous formulated small molecule calcium release-activated calcium (CRAC) channel inhibitors for the treatment of acute pancreatitis, asparaginase-induced pancreatic toxicity, and acute kidney injury, as well as severe COVID-19 pneumonia. The company also develops Auxora for the treatment of ulcerative colitis, traumatic brain injury, and allergic asthma; and oral CRAC channel inhibitors for use in chronic inflammatory and immunologic disease. The company is based in La Jolla, California.

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