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UroGen Pharma Ltd. (URGN) Stock Analysis

Healthcare

UroGen Pharma Ltd.

$29.46

+$0.57 (+1.97%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

UroGen Pharma Ltd. operates within the healthcare sector as a biotechnology company dedicated to the development and commercialization of therapeutic solutions specifically for urothelial and specialty cancers. The firm leverages its proprietary technology, RTGel, which utilizes a novel polymeric biocompatible, reverse thermal gelation hydrogel technology, alongside Mitomycin, a generic drug utilized off-label to address specific treatment needs. The company currently maintains a market capitalization of $855.83M and employs a workforce of 291 individuals to support its R&D and commercial operations. With annual revenue reaching $109.79M, the market cap indicates that the market values the company at a premium relative to its current sales, reflecting high expectations for the potential commercial success of its pipeline in the specialized oncology space.

Financial Health

The company reported revenue of $109.79M for the trailing twelve months, yet this figure stands in stark contrast to a net income of -$153.49M and an EBITDA of -$124.55M, revealing a significant gap where operating expenses heavily outweigh earnings before interest, taxes, depreciation, and amortization. This disparity highlights a cost structure characterized by substantial investment in research and development or commercialization activities that has not yet translated into profitable operations. Free cash flow stands at -$99.42M, indicating that the company is consuming cash reserves to fund its strategic initiatives rather than generating surplus liquidity for distribution or debt reduction. Despite these outflows, the balance sheet retains $120.46M in cash against $130.09M in total debt, suggesting a leveraged position where liabilities slightly exceed liquid assets. The debt-to-equity ratio is not available, but the negative price-to-book ratio of -8.06 further underscores the challenges in valuing the firm's tangible equity against its obligations. Liquidity is supported by a current ratio of 4.01, which implies that the company holds more than four times the value of current assets compared to its current liabilities, providing a buffer for short-term obligations. Return on equity is not available due to the lack of traditional earnings, while return on assets stands at -32.1%, indicating that the company's asset base is currently generating negative returns relative to its total capitalization.

Valuation Assessment

The trailing twelve-month P/E ratio is not available, whereas the forward P/E is 19.06, implying that the market prices the stock based on anticipated future earnings rather than historical performance. The price-to-book ratio is -8.06, which indicates a negative market premium over book value, suggesting that the market valuation is significantly detached from the company's tangible net asset position. Alternative valuation metrics provide further insight, with a price-to-sales ratio of 7.80 and an EV/EBITDA of -6.96, suggesting that investors are valuing the company primarily on revenue generation potential rather than profitability or cash flow generation. The stock has exhibited high volatility, trading between a 52-week high of $30.00 and a low of $3.42, placing the current trading range well below the recent peak. The beta of 1.37 indicates that the stock price is 37% more volatile than the broader market, reflecting the inherent risks associated with early-stage biotechnology development and commercialization.

Growth & Income

Revenue growth year-over-year is 54.0%, while earnings growth is not available due to the company's negative net income history, implying that top-line expansion is occurring without a corresponding improvement in profitability. As the company does not pay dividends, evidenced by a dividend yield of N/A and a payout ratio of 0.0%, it currently reinvests all available resources back into operations rather than returning capital to shareholders. This non-dividend strategy is typical for biotechnology firms that must prioritize funding their development pipelines and commercialization efforts over income distribution. The overall profile suggests a high-growth, non-income asset where value accrual is tied entirely to future product approvals and commercial success rather than current cash returns.

Peer Comparison

UroGen Pharma Ltd. (URGN) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
UroGen Pharma Ltd. URGN $1.44B N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. UroGen Pharma Ltd. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About UroGen Pharma Ltd.

UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty cancers. It offers RTGel, a novel proprietary polymeric biocompatible, reverse thermal gelation hydrogel technology; Mitomycin a generic drug used off-label as an adjuvant chemotherapy for the treatment of low-grade NMIBC after trans-urethral resection of bladder tumor; Zusduri, a sustained-release formulation of mitomycin for the treatment of non-muscle invasive bladder cancer (NMIBC); and Jelmyto for pyelocalyceal solutions. The company's lead product candidates are UGN-103, which is in phase 3 of clinical trial for intravesical solution; and UGN-104 that is in phase 3 of clinical trial for pyelocalyceal solution designed for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial cancer and low-grade intermediate risk NMIBC. It is also developing UGN-301, UGN-301+UGN 201, and UGN-301+gemcitabine that are in phase 1 of clinical trial for the treatment of high-grade NMIBC. The company has license agreement with Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; and licensing and supply agreement with medac Gesellschaft für klinische Spezialpräparate m.b.H. to develop UGN-103 and UGN-104. UroGen Pharma Ltd. was incorporated in 2004 and is headquartered in Princeton, New Jersey.

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Key Statistics

Market Cap
$1.44B
P/E Ratio
N/A
52-Week High
$32.37
52-Week Low
$3.60
Avg Volume
887.91K
Beta
1.59

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
298