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NASDAQ · Biotechnology · USD

Tenaya Therapeutics, Inc. (TNYA) Stock Analysis

Tenaya Therapeutics, Inc. (TNYA) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

TNYA

$0.39

−$0.02 (−4.83%)

Oct 21, 2026 · Market close

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Price History

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TNYA Key Statistics

As of Oct 21, 2026
Trading
Open
$0.41
Previous Close
$0.41
Day's Range
0.39–0.42
52-Week Range
0.36–1.84
Volume
2.16M
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
2.88
Valuation
Market Cap
$87.49M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
65.54
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.52
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$90.60M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
224.23M
1-Year Return
−78.68%
Dividend and dates
Earnings Date
November 11, 2026estimated
Avg Volume
2.71M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, TNYA closed at $0.39, −78.68% over 1 year.

Tenaya Therapeutics, Inc. (TNYA) has a market capitalization of $87.49M.

In fiscal 2025, TNYA reported revenue of $0.00.

TNYA Stock Return by Calendar Year

Tenaya Therapeutics, Inc. (TNYA) return since Jul 2021: what $10,000 became

1 year
$10,000 $2,132
−78.68%
5 years
$10,000 $189
−98.11%
Since Jul 2021
$10,000 $254
−97.46%

If you had invested $10,000 in Tenaya Therapeutics, Inc. (TNYA) at the close on July 30, 2021, the earliest close on record here, it would have been worth $254 at the close on October 21, 2026: −97.46% in total, −50.47% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−45.20%
2025−50.21%
2024−55.86%
2023+61.19%
2022−89.39%
2021 (partial year)+23.45%

As of October 21, 2026.

TNYA Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$90.60M—
2024$0.00−$111.13M—
2023$0.00−$124.08M—
2022$0.00−$123.67M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$93.33M−$90.60M—
2024$0.00—−$115.95M−$111.13M—
2023$0.00—−$131.19M−$124.08M—
2022$0.00—−$125.62M−$123.67M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

TNYA Valuation vs Biotechnology Median

Median of 608 stocks
MetricTNYABiotechnology medianvs median
P/S ratio65.5413.304.9x the median

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values Tenaya Therapeutics, Inc. (TNYA) at $87.49M. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 70.

TNYA last closed at $0.39 on October 21, 2026. That is −$0.02 (−4.83%) against the previous close. Over the past 52 weeks the price has ranged from $0.36 to $1.84. The latest close sits 8.39% above that 52-week low.

Financial Health

In fiscal 2025, Tenaya Therapeutics, Inc. reported revenue of $0.00. The same year closed with a net loss of $90.60M. Earnings per share on a trailing basis come to −0.52.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative. The price-to-sales ratio is 65.54. On price-to-sales that is 4.9 times the Biotechnology median of 13.3. 608 Biotechnology companies report these metrics, and the medians quoted come from that group.

Beta against the wider market is reported at 2.88. Annualized volatility over the trailing 5 years is 106.01%. The trailing one-year total return is −78.68%. Across 5 years the annualized return works out at −54.79%.

Growth & Income

No dividend is on file for TNYA.

2026 is still running; the total return is −45.20% year to date. Across the complete calendar years on file, 2023 returned +61.19% and 2022 returned −89.39%. Of the 4 complete calendar years on file, 1 finished higher.

Peer Comparison

Tenaya Therapeutics, Inc. (TNYA) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Tenaya Therapeutics, Inc. TNYA $87.49M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Tenaya Therapeutics, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Tenaya Therapeutics, Inc.

Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial. The company develops its products through gene addition, gene editing, gene silencing, and cellular regeneration. It has a research collaboration agreement with Alnylam Pharmaceuticals, Inc. to identify and validate novel gene targets for the potential treatment of cardiovascular disease. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.

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