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NASDAQ · Biotechnology · USD

ProMIS Neurosciences, Inc. (PMN) Stock Analysis

ProMIS Neurosciences, Inc. (PMN) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

PMN

$9.13

+$1.04 (+12.86%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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PMN Key Statistics

As of Oct 21, 2026
Trading
Open
$8.18
Previous Close
$8.09
Day's Range
8.18–9.13
52-Week Range
6.27–27.40
Volume
7.49K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
−0.25
Valuation
Market Cap
$81.88M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−11.65
Financials (FY)
Revenue (FY)
$0.00
Net Income (FY)
−$39.72M−1,529.33%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
8.97M
1-Year Return
−17.00%
Dividend and dates
Earnings Date
November 13, 2026estimated
Avg Volume
68.73K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, PMN closed at $9.13, −17.00% over 1 year.

ProMIS Neurosciences, Inc. (PMN) has a market capitalization of $81.88M.

In fiscal 2025, PMN reported revenue of $0.00.

PMN Stock Return by Calendar Year

ProMIS Neurosciences, Inc. (PMN) 10-year return: what $10,000 became

1 year
$10,000 $8,300
−17.00%
5 years
$10,000 $406
−95.94%
10 years
$10,000 $609
−93.91%

If you had invested $10,000 in ProMIS Neurosciences, Inc. (PMN) 10 years ago, at the close on October 21, 2016, it would have been worth $609 at the close on October 21, 2026: −93.91% in total, −24.41% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+33.67%
2025−71.24%
2024−17.39%
2023−73.50%
2022−34.24%
2021+37.50%
2020−38.46%
2019−35.00%
2018+17.65%
2017+70.00%
2016 (partial year)−9.09%

As of October 21, 2026.

PMN Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$0.00−$39.72M—
2024$0.00$2.78M—
2023$0.00−$13.21M—
2022$0.00−$18.06M—
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$0.00—−$40.17M−$39.72M—
2024$0.00—−$16.83M$2.78M—
2023$0.00—−$14.26M−$13.21M—
2022$0.00—−$23.38M−$18.06M—

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

All 10 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

ProMIS Neurosciences, Inc. (PMN) is capitalised at $81.88M on the latest close. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 10.

The most recent close on file for PMN is $9.13, dated October 21, 2026. That is +$1.04 (+12.86%) against the previous close. Over the past 52 weeks the price has ranged from $6.27 to $27.40. The latest close sits 45.61% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $0.00. The same year closed with a net loss of $39.72M. Trailing earnings per share are −11.65.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $0.00 in 2025. Of those 4 years, 1 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published.

The trailing one-year total return is −17.00%. Measured over 10 years, that is −24.41% a year compounded. Beta against the wider market is reported at −0.25. Annualized volatility over the trailing 10 years is 123.34%.

Growth & Income

No dividend is on file for PMN.

The strongest complete calendar year on file is 2017 at +70.00%; the weakest is 2023 at −73.50%. Of the 9 complete calendar years on file, 3 finished higher. So far in 2026 the total return is +33.67%.

Peer Comparison

ProMIS Neurosciences, Inc. (PMN) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
ProMIS Neurosciences, Inc. PMN $81.88M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. ProMIS Neurosciences, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About ProMIS Neurosciences, Inc.

ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines for neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS, which enables drug discovery through a combination of protein biology, physics, and supercomputing. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers for treating Alzheimer's disease; PMN267 for the treatment of amyotrophic lateral sclerosis; and PMN442, a mAb targeting toxic a-syn oligomers and seeding fibrils for treating multiple system atrophy. The company also develops PNM440, an alpha-synuclein vaccine for treating multiple synucleinopathies; and PMN311, an amyloid-beta vaccine for the treatment of Alzheimer's. In addition, it is developing therapies for frontotemporal lobar degeneration, Huntington's disease, progressive supranuclear palsy, corticobasal degeneration, and schizophrenia. The company was formerly known as Amorfix Life Sciences Ltd. and changed its name to ProMIS Neurosciences, Inc. in July 2015. ProMIS Neurosciences, Inc. is headquartered in Toronto, Canada.

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