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Jaguar Health, Inc. (JAGX) Stock Analysis

Healthcare

Jaguar Health, Inc.

$3.11

+$0.20 (+6.87%)

Last Updated: May 26, 2026

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Analysis

Company Overview

Jaguar Health, Inc. operates as a commercial-stage pharmaceuticals company dedicated to developing plant-based prescription medicines designed to alleviate gastrointestinal distress in both human patients and animals. The enterprise functions within the broader Healthcare sector and specifically targets the Biotechnology industry, where its focus lies in the research and commercialization of specialized therapeutic agents. As of the latest reporting period, the company maintains a market capitalization of $3.84M, generates annual revenue of $11.79M, and employs a workforce of 49 individuals. The combination of a sub-$4M market cap and revenue figures slightly exceeding $11M indicates that Jaguar Health occupies a niche position with limited scale relative to large-cap pharmaceutical peers, suggesting a business model that relies on high-margin, specialized product lines rather than broad-market volume sales.

Financial Health

The company reported revenue of $11.79M over the trailing twelve months, yet this revenue generated a net income of -$40,293,000, revealing a cost structure where operating expenses significantly exceed total revenue. This negative net income corresponds with an EBITDA of -$30,909,000, indicating that the core operations are currently burning cash despite generating top-line sales. Free cash flow stands at -$15,181,375, which implies that the company is utilizing its existing cash reserves to fund operations and development rather than generating surplus liquidity for debt reduction or shareholder returns. The company holds $3.53M in cash against $31.90M in debt, resulting in a debt-to-equity ratio of 731.82, which characterizes the balance sheet as highly leveraged and reliant on future financing or operational turnaround to meet obligations. Profitability metrics reflect this financial stress, with a gross margin of 81.9% demonstrating strong pricing power or low cost of goods sold, contrasted sharply by an operating margin of -234.8% and a profit margin of 0.0%. The return on equity is calculated at -411.6% and the return on assets sits at -38.0%, metrics that indicate that management is currently deploying capital in a manner that destroys value rather than generating positive returns. Furthermore, the current ratio of 0.81 suggests that the company possesses fewer current assets than current liabilities, signaling potential short-term liquidity challenges as it seeks to settle its immediate financial commitments.

Valuation Assessment

Valuation multiples for Jaguar Health reflect its lack of profitability, with a trailing P/E ratio listed as N/A and a forward P/E of -0.06, implying that traditional earnings-based valuation models are not applicable and that the market is pricing the stock based on assets or future potential rather than current earnings. The price-to-book ratio is 0.40, indicating that the market values the company at less than half of its book value, which often suggests the market perceives significant risks or that the asset base may be undervalued relative to the equity claims. Alternative valuation metrics further highlight the company's financial distress, as the price-to-sales ratio is 0.33 and the EV/EBITDA is -1.00, suggesting that the stock is priced at a deep discount relative to its sales and adjusted earnings. Regarding trading range volatility, the 52-week high was $15.48 and the 52-week low was $0.34, meaning the current price sits significantly closer to the bottom of the trading range, reflecting a prolonged period of depressed valuation. The beta value is recorded at 0.05, which indicates that the stock price exhibits extremely low volatility relative to the broader market, moving independently of general market trends and suggesting a defensive or speculative characteristic rather than a cyclical one.

Growth & Income

Revenue growth for the year-over-year period was -0.8%, while earnings growth is listed as N/A, indicating that the company is currently shrinking rather than expanding its top line and has no positive earnings trajectory to measure. Because earnings are negative, the concept of earnings growth is not applicable in the traditional sense, and the decline in revenue suggests a contraction in the commercialization of its plant-based medicines. Regarding income distributions, the company does not pay a dividend, evidenced by a dividend yield of N/A and a payout ratio of 0.0%, which means the company retains all its earnings (or rather, its losses) to attempt to fund operations and development initiatives. Consequently, the overall growth and income profile for Jaguar Health is defined by revenue contraction and a total absence of income generation, leaving shareholders with no current yield and exposure to a shrinking revenue base as the company navigates its commercial-stage challenges.

Peer Comparison

Jaguar Health, Inc. (JAGX) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Jaguar Health, Inc. JAGX $1.88M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Jaguar Health, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Jaguar Health, Inc.

Jaguar Health, Inc., a commercial-stage pharmaceuticals company, focuses on developing plant-based prescription medicines for people and animals with gastrointestinal distress. It operates through two segments, Animal Health and Human Health. The company focuses on developing and commercializing prescription and non-prescription products for companion and production animals; and human products. Its lead prescription drug is Mytesi, an anti-secretory antidiarrheal drug for the symptomatic relief of non-infectious diarrhea in adults with HIV/AIDS on antiretroviral therapy; and Canalevia-CA1, a prescription drug product for chemotherapy-induced diarrhea in dogs. It is also developing Crofelemer, an anti-secretory antidiarrheal drug, which is in Phase III clinical trial for prophylaxis of diarrhea in adult cancer patients; Phase II clinical trials for rare/orphan disease indications, including short bowel syndrome with intestinal failure and microvillus inclusion disease; diarrhea-predominant irritable bowel syndrome; and for idiopathic/functional diarrhea. In addition, the company is developing Mytesi which is in Phase III clinical trial for cancer therapy-related diarrhea, as well as Phase II clinical trial for irritable bowel syndrome; and NP-300, a second-generation antidiarrheal drug that is in Phase I clinical trial for symptomatic relief and treatment of moderate-to-severe diarrhea. The company is headquartered in San Francisco, California.

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Key Statistics

Market Cap
$1.88M
P/E Ratio
N/A
52-Week High
$171.50
52-Week Low
$2.53
Avg Volume
62.06K
Beta
0.03

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
47