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NASDAQ · Biotechnology · USD

Inovio Pharmaceuticals, Inc. (INO) Stock Analysis

Inovio Pharmaceuticals, Inc. (INO) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

INO

$0.80

−$0.21 (−21.26%)

Oct 21, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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INO Key Statistics

As of Oct 21, 2026
Trading
Open
$1.08
Previous Close
$1.01
Day's Range
0.80–1.08
52-Week Range
0.56–2.72
Volume
11.37M
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.61
Valuation
Market Cap
$82.23M
P/E Ratio
unprofitable
EPS (ttm)Profit attributable to each share over the last twelve months.
−0.90
Financials (FY)
Revenue (FY)
$65.34K−69.99%
Net Income (FY)
−$84.95M
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
103.40M
1-Year Return
−65.87%
Dividend and dates
Earnings Date
November 10, 2026estimated
Avg Volume
4.24M

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, INO closed at $0.80, −65.87% over 1 year.

Inovio Pharmaceuticals, Inc. (INO) has a market capitalization of $82.23M.

In fiscal 2025, INO reported revenue of $65.34K.

INO Stock Return by Calendar Year

Inovio Pharmaceuticals, Inc. (INO) 10-year return: what $10,000 became

1 year
$10,000 $3,413
−65.87%
5 years
$10,000 $94
−99.06%
10 years
$10,000 $79
−99.21%

If you had invested $10,000 in Inovio Pharmaceuticals, Inc. (INO) 10 years ago, at the close on October 21, 2016, it would have been worth $79 at the close on October 21, 2026: −99.21% in total, −38.35% a year. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)−54.29%
2025−4.92%
2024−70.10%
2023−67.31%
2022−68.74%
2021−43.62%
2020+168.18%
2019−17.50%
2018−3.15%
2017−40.49%
2016 (partial year)−25.78%

As of October 21, 2026.

INO Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$65.34K−$84.95M−130,000.0%
2024$217.76K−$107.25M−49,254.3%
2023$832.01K−$135.12M−16,239.9%
2022$10.26M−$279.82M−2,726.7%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$65.34K—−$86.82M−$84.95M−130,000.0%
2024$217.76K—−$112.40M−$107.25M−49,254.3%
2023$832.01K—−$133.43M−$135.12M−16,239.9%
2022$10.26M—−$267.57M−$279.82M−2,726.7%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

Recent News

All 16 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Inovio Pharmaceuticals, Inc. (INO) is capitalised at $82.23M on the latest close. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 112.

The most recent close on file for INO is $0.80, dated October 21, 2026. That is −$0.21 (−21.26%) against the previous close. Over the past 52 weeks the price has ranged from $0.56 to $2.72. The latest close sits 42.02% above that 52-week low.

Financial Health

In fiscal 2025, Inovio Pharmaceuticals, Inc. reported revenue of $65.34K. Against the prior fiscal year total of $217.76K, that is a change of −69.99%. The same year closed with a net loss of $84.95M. Earnings per share on a trailing basis come to −0.9.

Across the 4 fiscal years on file, revenue moves from $10.26M in 2022 to $65.34K in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative.

The reported beta is 1.61. Daily returns over the trailing 10 years annualize to a volatility of 94.95%. Over the trailing twelve months the total return is −65.87%. Across 10 years the annualized return works out at −38.35%.

Growth & Income

No dividend is on file for INO.

Across the complete calendar years on file, 2020 returned +168.18% and 2024 returned −70.10%. Of the 9 complete calendar years on file, 1 finished higher. So far in 2026 the total return is −54.29%.

Peer Comparison

Inovio Pharmaceuticals, Inc. (INO) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Inovio Pharmaceuticals, Inc. INO $82.23M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Inovio Pharmaceuticals, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Inovio Pharmaceuticals, Inc.

Inovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses SynCon, to help engineer precisely designed plasmid DNA plasmids, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. The company's lead product candidate is INO-3107 for HPV-related recurrent respiratory papillomatosis and is under Phase 1/2 trial. Its products in pipeline include VGX-3100 for the treatment of HPV-related cervical high-grade squamous intraepithelial lesions; INO-3112 for the treatment of HPV-related Oropharyngeal squamous cell carcinoma and is under Phase 2 trial; INO-5401 for the treatment of glioblastoma multiforme and is under Phase 2 trial; INO-4201 for Ebola Virus Disease and is under Phase 1b trial; INO-4800 for COVID-19 and is under Phase 2/3 trial; and INO-6160 for the treatment of human immunodeficiency virus and is under Phase 1 trial. The company's partners and collaborators ApolloBio Corporation, AstraZeneca, Coherus Biosciences, Defense Advanced Research Projects Agency, HIV Vaccines Trial Network, Kaneka Eurogentec, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Plumbline Life Sciences, Regeneron Pharmaceuticals, Richter BioLogics, the University of Pennsylvania, and The Wistar Institute. The company was incorporated in 1983 and is headquartered in Plymouth Meeting, Pennsylvania.

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