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NASDAQ · Biotechnology · USD

SeaStar Medical Holding Corporation (ICU) Stock Analysis

SeaStar Medical Holding Corporation (ICU) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

ICU

$2.98

+$0.07 (+2.41%)

Sep 4, 2026 · Market close

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Price History

Hover for the daily close. The dotted line marks the period open.

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ICU Key Statistics

As of Sep 4, 2026
Trading
Open
$2.84
Previous Close
$2.91
Day's Range
2.84–3.01
52-Week Range
2.07–12.50
Volume
25.50K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
−1.03
Valuation
Market Cap
$13.13M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
7.67
EPS (ttm)Profit attributable to each share over the last twelve months.
−1.94
Financials (FY)
Revenue (FY)
$1.23M+814.07%
Net Income (FY)
−$12.15M
Profit marginThe share of revenue left as profit after all costs and taxes.
0.00%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
4.41M
1-Year Return
−63.61%
Dividend and dates
Avg Volume
85.51K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

ICU Stock Return by Calendar Year

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+24.17%
2025−87.63%
2024−82.48%
2023−89.20%
2022−59.16%
2021 (partial year)+2.45%

As of September 4, 2026.

ICU Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$1.23M−$12.15M−984.6%
2024$135.00K−$24.83M−18392.6%
2023$0.00−$26.23M
2022$0.00−$12.19M
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$1.23M$1.18M−$12.18M−$12.15M−984.6%
2024$135.00K$135.00K−$17.84M−$24.83M−18392.6%
2023$0.00$0.00−$14.21M−$26.23M
2022$0.00−$11.61M−$12.19M

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

ICU Valuation vs Biotechnology Median

Median of 656 stocks
MetricICUBiotechnology medianvs median
P/S ratio7.6715.2650% below
Profit margin0.00%0.00%0.0 pts above

Medians across 656 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of September 4, 2026.

Recent News

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

The market values SeaStar Medical Holding Corporation (ICU) at $13.13M. It is classified in the Biotechnology industry, within the Healthcare sector. Headcount on file is 18.

ICU last closed at $2.98 on September 4, 2026. That is +$0.07 (+2.41%) against the previous close. Over the past 52 weeks the price has ranged from $2.07 to $12.50. The latest close sits 43.96% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $1.23M. That is +814.07% against the prior fiscal year, when revenue was $135.00K. The same year closed with a net loss of $12.15M. The reported profit margin is 0%. Trailing earnings per share are −1.94.

Across the 4 fiscal years on file, revenue moves from $0.00 in 2022 to $1.23M in 2025. Of those 4 years, 0 report positive net income.

Valuation Assessment

No trailing P/E applies: the last reported earnings figure is negative. Measured against sales, the shares trade at 7.67 times revenue. On price-to-sales that is 49.78% below the Biotechnology median of 15.26. 656 Biotechnology companies report these metrics, and the medians quoted come from that group.

Over the trailing twelve months the price has returned −63.61%. Measured over 5 years, that is −73.95% a year compounded. Beta against the wider market is reported at −1.03. Daily returns over the trailing 5 years annualize to a volatility of 131.6%.

Growth & Income

No dividend is on file for ICU.

2026 is still running; the price is +24.17% year to date. The strongest complete calendar year on file is 2022 at −59.16%; the weakest is 2023 at −89.20%. Of the 4 complete calendar years on file, 0 finished higher.

Peer Comparison

SeaStar Medical Holding Corporation (ICU) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
SeaStar Medical Holding Corporation ICU $13.13M
Vertex Pharmaceuticals Incorporated VRTX $138.42B 32.5
Regeneron Pharmaceuticals, Inc. REGN $85.22B 20.5
argenx SE ARGX $64.25B 40.1

The Biotechnology industry average P/E ratio is 12.6x. SeaStar Medical Holding Corporation has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each nightly rebuild. Informational only, not financial advice. As of September 4, 2026.

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About SeaStar Medical Holding Corporation

SeaStar Medical Holding Corporation, a commercial-stage healthcare company, develops a proprietary platform therapy to reduce the consequences of hyperinflammation on vital organs in the United States. The company offers the selective cytopheretic device (SCD), which is a disease-modifying device that neutralizes over-active immune cells and stops the cytokine storm that yields destructive hyperinflammation; and QUELIMMUNE, an SCD therapy for pediatric patients with acute kidney injury (AKI) due to sepsis. It also develops NEUTRALIZE-AKI, an SCD therapy that is in clinical trials for adult patients with AKI; and other products in various therapeutic areas, including cardiorenal syndrome, hepatorenal syndrome, and myocardial stunning in end-stage renal disease. SeaStar Medical Holding Corporation was founded in 2007 and is headquartered in Denver, Colorado.

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