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NASDAQ · Biotechnology · USD

Precision BioSciences, Inc. (DTIL) Stock Analysis

Precision BioSciences, Inc. (DTIL) is a Biotechnology stock listed on NASDAQ and quoted in US Dollar.

Last Updated: October 21, 2026

DTIL

$6.71

+$0.15 (+2.29%)

Oct 21, 2026 · Market close

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Price History

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DTIL Key Statistics

As of Oct 21, 2026
Trading
Open
$6.62
Previous Close
$6.56
Day's Range
6.55–6.86
52-Week Range
3.53–9.62
Volume
231.04K
BetaHow much the share price moves relative to the wider market. 1.0 moves in line with it; above 1.0 swings more, below 1.0 less.
1.28
Valuation
Market Cap
$185.21M
P/E Ratio
unprofitable
P/S ratioMarket value divided by annual revenue. Useful for companies that are not yet profitable, where a P/E cannot be calculated.
4.11
EPS (ttm)Profit attributable to each share over the last twelve months.
−1.35
Financials (FY)
Revenue (FY)
$34.26M−50.12%
Net Income (FY)
−$45.72M−737.98%
Profit marginThe share of revenue left as profit after all costs and taxes.
−117.04%
Shares OutstandingThe total number of shares held by all investors. Market value is this figure multiplied by the share price.
27.60M
1-Year Return
−4.01%
Dividend and dates
Earnings Date
November 2, 2026estimated
Avg Volume
261.43K

Only metrics the company reports are shown. Data provided by Yahoo Finance via yfinance. Updated daily.

Key facts

As of October 21, 2026, DTIL closed at $6.71, −4.01% over 1 year.

Precision BioSciences, Inc. (DTIL) has a market capitalization of $185.21M.

In fiscal 2025, DTIL reported revenue of $34.26M.

DTIL Stock Return by Calendar Year

Precision BioSciences, Inc. (DTIL) return since Mar 2019: what $10,000 became

1 year
$10,000 $9,599
−4.01%
5 years
$10,000 $232
−97.68%
Since Mar 2019
$10,000 $128
−98.72%

If you had invested $10,000 in Precision BioSciences, Inc. (DTIL) at the close on March 28, 2019, the earliest close on record here, it would have been worth $128 at the close on October 21, 2026: −98.72% in total, −43.77% a year, over a partial period shorter than 10 years. A historical calculation from closing prices adjusted for splits and dividends, before fees and taxes.

Calendar-year returns computed from daily closing prices. Partial years are shown muted and marked with an asterisk.

YearReturn
2026 (partial year)+61.30%
2025+9.19%
2024−65.21%
2023−69.33%
2022−83.92%
2021−11.27%
2020−39.96%
2019 (partial year)−20.36%

As of October 21, 2026.

DTIL Revenue and Earnings by Fiscal Year

FY ends December
Fiscal yearRevenueNet incomeNet margin
2025$34.26M−$45.72M−133.4%
2024$68.70M$7.17M10.4%
2023$48.73M−$61.32M−125.8%
2022$25.10M−$111.64M−444.8%
Fiscal yearRevenueGross profitOperating incomeNet incomeNet margin
2025$34.26M—−$52.15M−$45.72M−133.4%
2024$68.70M—−$26.16M$7.17M10.4%
2023$48.73M—−$43.74M−$61.32M−125.8%
2022$25.10M—−$62.31M−$111.64M−444.8%

Annual figures as reported, in the company's reporting currency. As of December 31, 2025.

DTIL Valuation vs Biotechnology Median

Median of 608 stocks
MetricDTILBiotechnology medianvs median
P/S ratio4.1113.300.3x the median
Profit margin−117.04%−38.31%78.7 pts below

Medians across 608 Biotechnology stocks that report the metric. Medians, not averages, so one outlier cannot move them. As of October 21, 2026.

Recent News

All 7 articles ↓

News provided by third-party sources. Not financial advice.

Analysis

Data-derived

Company Overview

Precision BioSciences, Inc. (DTIL) carries a market capitalisation of $185.21M. It is classified in the Biotechnology industry, within the Healthcare sector. The company reports 67 employees.

DTIL last closed at $6.71 on October 21, 2026. That is +$0.15 (+2.29%) against the previous close. The 52-week range on file runs from $3.53 to $9.62. The latest close sits 90.08% above that 52-week low.

Financial Health

Fiscal 2025 revenue came to $34.26M. Against the prior fiscal year total of $68.70M, that is a change of −50.12%. The same year closed with a net loss of $45.72M. The reported profit margin is −117.04%. That is 78.7 percentage points below the Biotechnology median of −38.31%. Trailing earnings per share are −1.35.

Across the 4 fiscal years on file, revenue moves from $25.10M in 2022 to $34.26M in 2025. Of those 4 years, 1 report positive net income.

Valuation Assessment

The record shows negative trailing earnings, so no price-to-earnings ratio is published. The price-to-sales ratio is 4.11. On price-to-sales that is 0.3 times the Biotechnology median of 13.3. 608 Biotechnology companies report these metrics, and the medians quoted come from that group.

The trailing one-year total return is −4.01%. Across 5 years the annualized return works out at −52.89%. Beta against the wider market is reported at 1.28. Annualized volatility over the trailing 7 years is 84.83%.

Growth & Income

The record shows no dividend for DTIL.

So far in 2026 the total return is +61.30%. The strongest complete calendar year on file is 2025 at +9.19%; the weakest is 2022 at −83.92%. Of the 6 complete calendar years on file, 1 finished higher.

Peer Comparison

Precision BioSciences, Inc. (DTIL) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Precision BioSciences, Inc. DTIL $185.21M —
Vertex Pharmaceuticals Incorporated VRTX $132.95B 30.4
Moderna, Inc. MRNA $98.14B —
Regeneron Pharmaceuticals, Inc. REGN $82.95B 19.9

The Biotechnology industry average P/E ratio is 16.6x. Precision BioSciences, Inc. has no P/E ratio because it is not currently profitable.

Every figure above is read from this page's own data on each daily rebuild. Informational only, not financial advice. As of October 21, 2026.

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About Precision BioSciences, Inc.

Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; and PBGENE-DMD (Excision) for the treatment of Duchenne muscular dystrophy. In addition, the company develops PBGENE-3243 for the treatment of m.3243 associated mitochondrial diseases; and iECURE-OTC (Insertion) for ornithine transcarbamylase deficiency. It has collaboration agreements with TG Cell Therapy, Inc. to develop, manufacture, and commercialize azercabtagene zapreleucel for autoimmune diseases and other indications; and iECURE, Inc., an ARCUS-mediated targeted gene insertion. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.

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