StockVS

Precision BioSciences, Inc. (DTIL) Stock Analysis

Healthcare

Precision BioSciences, Inc.

$7.58

+$0.35 (+4.84%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Precision BioSciences, Inc. operates as a clinical stage gene editing company focused on developing in vivo gene editing therapies within the United States, specifically targeting gene edits that include insertion, excision, and elimination. The company functions within the Healthcare sector and the Biotechnology industry, positioning itself as a specialized developer of ARCUS, a genome editing platform capable of DNA genome insertion, removal, and repair. The firm currently maintains a market capitalization of $159.98M, generates annual revenue of $34.26M, and employs 68 individuals to execute its research and development objectives. These financial figures indicate a mid-cap biotechnology entity that has achieved significant revenue expansion while maintaining a relatively lean operational workforce, suggesting a capital-intensive growth model typical of the early-to-mid stages of biotechnology development where revenue scales rapidly to fund clinical trials and platform expansion.

Financial Health

The company reports a trailing twelve-month revenue of $34.26M alongside a net income of -$46,609,000 and an EBITDA of -$50,680,000, revealing a cost structure where operating expenses and R&D investments substantially exceed current revenue generation. This negative net income relative to revenue highlights the inherent burn rate of a clinical-stage enterprise investing heavily in platform development before reaching commercial profitability. Free cash flow stands at -$21,974,250, indicating that the company is currently burning cash, which implies a reliance on external capital markets or existing cash reserves to fund ongoing operations and pipeline progression. The firm holds $115.58M in cash against $28.81M in debt, supported by a debt-to-equity ratio of 31.23, presenting a balance sheet that appears conservative regarding leverage despite the negative earnings profile. Profit margins reflect the pre-commercial nature of the business, with a gross margin of 100.0% suggesting high-value intellectual property and low cost of goods sold, contrasted by an operating margin of 36.6% and a profit margin of -133.4% driven by the significant net loss. Liquidity is robust, evidenced by a current ratio of 13.32, which indicates the company possesses more than thirteen times the current assets necessary to cover its short-term liabilities without immediate distress. Return metrics show a return on equity of -62.7% and a return on assets of -22.4%, revealing that management is currently deploying capital to generate negative returns as the business scales its clinical pipeline rather than distributing profits.

Valuation Assessment

Valuation metrics for the company reflect its status as a loss-making growth entity, with a trailing P/E ratio of N/A and a forward P/E of -1.90, implying that traditional earnings-based valuation models are not yet applicable due to negative earnings and that the market is pricing in future potential rather than current profitability. The price-to-book ratio is recorded at 1.69, indicating that the market values the company at a 69% premium over its book value, which often occurs in biotechnology when investors assign high value to intangible assets like intellectual property and clinical data not fully captured on the balance sheet. Alternative valuation measures include a price-to-sales ratio of 4.67 and an EV/EBITDA of -1.44, suggesting the market is willing to pay a significant multiple of sales to acquire the revenue streams generated by the ARCUS platform. The stock has traded between a 52-week high of $8.82 and a 52-week low of $3.53, meaning the current trading price sits within a range where the upper limit suggests a potential ceiling based on recent volatility while the lower limit establishes a floor of support. The stock exhibits a beta of 1.32, meaning its price volatility is approximately 32% higher than the broader market, reflecting the heightened sensitivity of biotechnology equities to sector-specific developments and clinical trial outcomes.

Growth & Income

Revenue growth over the past year stands at an extraordinary 5261.1%, while earnings growth is listed as N/A due to the company's continued net losses, implying that top-line expansion is outpacing profitability as the company scales its commercial operations. Since the company does not pay dividends, the dividend yield is N/A and the payout ratio is 0.0%, confirming that the firm retains all earnings and cash flow to reinvest into its research and development efforts rather than distributing income to shareholders. This reinvestment strategy is standard for clinical-stage biotechnology firms that prioritize expanding their pipeline and advancing their gene editing platform over providing income to investors. The overall growth and income profile is characterized by explosive revenue expansion and a complete absence of dividend income, relying entirely on capital appreciation potential and future commercial success to generate value for equity holders.

Peer Comparison

Precision BioSciences, Inc. (DTIL) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Precision BioSciences, Inc. DTIL $195.58M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Precision BioSciences, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Precision BioSciences, Inc.

Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; and PBGENE-DMD (Excision) for the treatment of Duchenne muscular dystrophy. In addition, the company develops PBGENE-3243 for the treatment of m.3243 associated mitochondrial diseases; and iECURE-OTC (Insertion) for ornithine transcarbamylase deficiency. It has collaboration agreements with TG Cell Therapy, Inc. to develop, manufacture, and commercialize azercabtagene zapreleucel for autoimmune diseases and other indications; and iECURE, Inc., an ARCUS-mediated targeted gene insertion. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.

Visit website →

Key Statistics

Market Cap
$195.58M
P/E Ratio
N/A
52-Week High
$8.82
52-Week Low
$3.53
Avg Volume
281.31K
Beta
1.31

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
66