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Cabaletta Bio, Inc. (CABA) Stock Analysis

Healthcare

Cabaletta Bio, Inc.

$3.72

+$0.07 (+1.92%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Cabaletta Bio, Inc. operates as a clinical-stage biotechnology entity dedicated to the discovery and development of engineered T cell therapies specifically designed for patients suffering from autoimmune diseases. The company functions within the broader healthcare sector and the specialized biotechnology industry, a landscape defined by high capital requirements, rigorous regulatory pathways, and a focus on innovative cell-based treatments that aim to address unmet medical needs. At its current scale, the company maintains a market capitalization of $267.62M and employs a workforce of 154 individuals to support its research and development initiatives. The combination of a market cap under $300 million and a lack of reported annual revenue indicates that Cabaletta Bio is in a pre-commercialization phase where value is derived primarily from intellectual property potential and pipeline progression rather than current sales performance.

Financial Health

The financial profile of Cabaletta Bio, Inc. is characterized by significant negative earnings, with a net income of $-167,856,000 and an EBITDA of $-170,595,008, while reported revenue remains N/A. The substantial gap between the zero revenue figure and the deep net loss reveals a cost structure dominated by heavy research and development expenditures and operational burn typical of clinical-stage ventures that have not yet achieved commercial product sales. The company generates a free cash flow of $-81,283,128, a metric that highlights its ongoing consumption of cash reserves to fund operations and clinical trials, thereby limiting immediate financial flexibility for external expansion or shareholder returns. All three margin metrics reflect this pre-revenue status, with gross margin, operating margin, and profit margin all recorded at 0.0%, indicating that no revenue has been generated to support operating costs or generate profit. Regarding liquidity and leverage, the company holds $133.60M in cash against $27.10M in debt, supported by a current ratio of 2.77 which suggests a robust ability to meet short-term obligations with existing liquid assets. Despite the strong cash position relative to debt, the return on equity stands at -127.0% and the return on assets is -61.5%, metrics that reveal management is currently destroying shareholder value through high operational costs rather than generating returns, a necessary condition for development-stage companies but one that must be reversed upon commercialization.

Valuation Assessment

Valuation metrics for Cabaletta Bio, Inc. present a complex picture due to the absence of earnings, with a trailing twelve-month P/E ratio listed as N/A and a forward P/E of -1.78. The negative forward P/E ratio implies that analysts or data sources are projecting continued losses in the near term, making traditional earnings-based valuation methods inapplicable and suggesting the market prices the stock based on future pipeline potential rather than current profitability. The price-to-book ratio is recorded at 2.49, indicating that the market values the company at a significant premium over its book value, likely reflecting the high value placed on its intangible assets such as patents and clinical trial data. Alternative valuation measures include a price-to-sales ratio of N/A and an EV/EBITDA of -1.19, both of which suggest that the company cannot be valued using standard multiples due to its lack of sales and negative earnings before interest, taxes, depreciation, and amortization. Price volatility is evident in the 52-week range, where the stock has traded between a low of $0.99 and a high of $3.78, meaning the current valuation sits at a level that fluctuates significantly based on clinical data releases and market sentiment. The stock exhibits a beta of 3.28, which indicates that its price is highly volatile and expected to move with much greater intensity than the broader market, posing higher risk for investors compared to large-cap securities.

Growth & Income

Growth metrics for Cabaletta Bio, Inc. show revenue growth year-over-year as N/A and earnings growth year-over-year as N/A, reflecting the reality that the company has not yet generated sales to measure growth rates or compare earnings trajectory against revenue. Because the company is not a dividend payer, the dividend yield is N/A and the payout ratio is 0.0%, meaning the firm retains all available resources to reinvest into its drug development programs rather than distributing income to shareholders. The absence of a dividend policy is consistent with the company's life cycle stage, where earnings are negative and cash is prioritized for sustaining operations and advancing clinical trials rather than paying out returns. Consequently, the overall growth and income profile of Cabaletta Bio is defined entirely by the potential for future commercialization rather than current income generation or historical growth rates, creating a high-risk, high-reward dynamic where value creation depends on successfully transitioning from a clinical-stage asset to a revenue-generating product.

Peer Comparison

Cabaletta Bio, Inc. (CABA) operates in the Biotechnology industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Cabaletta Bio, Inc. CABA $606.56M N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

The Biotechnology industry average P/E ratio is 53.8x. Cabaletta Bio, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Cabaletta Bio, Inc.

Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with autoimmune diseases. The company's lead product candidate is resecabtagene autoleucel, a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T, which is in Phase 1/2 clinical trials for the treatment of dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, juvenile myositis, lupus nephritis, systemic lupus erythematosus, relapsing and progressive multiple sclerosis, mucocutaneous and mucosal pemphigus vulgaris (PV), systemic sclerosis, and generalized myasthenia gravis. It also develops DSG3-CAART, a CAAR T cell therapy that is in Phase 1 clinical trial for the treatment of mucosal PV; and MuSK-CAART, an investigational cell therapy in Phase 1 trial for treating patients with anti-muscle-specific kinase (MuSK) antibody positive myasthenia gravis. It has collaborations with the University of Pennsylvania and the Children's Hospital of Philadelphia; Nanjing IASO Biotherapeutics Co., Ltd; Oxford Biomedica; Autolus Holdings (UK) Limited; and WuXi Advanced Therapies, Inc. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.

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Key Statistics

Market Cap
$606.56M
P/E Ratio
N/A
52-Week High
$4.23
52-Week Low
$1.26
Avg Volume
2.99M
Beta
3.17

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
154