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Akebia Therapeutics, Inc. (AKBA) Stock Analysis

Healthcare

Akebia Therapeutics, Inc.

$1.04

+$0.02 (+1.96%)

Last Updated: May 26, 2026

Price History

Analysis

Company Overview

Akebia Therapeutics, Inc. operates as a biopharmaceutical company dedicated to the development and commercialization of therapeutics specifically designed for patients suffering from kidney diseases. The company functions within the Healthcare sector and the Drug Manufacturers - Specialty & Generic industry, a classification that highlights its focus on specialized medical treatments rather than broad consumer pharmaceuticals. This entity employs 194 individuals and maintains a total market capitalization of $372.35M, while generating annual revenue of $236.20M based on trailing twelve-month data. These financial figures indicate that Akebia Therapeutics holds a mid-cap position in the market, suggesting a company that has achieved sufficient scale to commercialize its product portfolio but still operates with the characteristics of a specialized, smaller-cap biotechnology firm rather than a large-cap diversified player.

Financial Health

The company reported revenue of $236.20M for the trailing twelve months, alongside a net income of -$5,345,000 and an EBITDA of $27.27M. The significant disparity between the positive EBITDA figure and the negative net income reveals a cost structure where non-operating expenses, such as interest payments or tax adjustments, are substantial enough to turn operational profitability into a net loss. Despite the net loss, the entity generated free cash flow of $68.61M, which provides critical financial flexibility to fund research and development activities and service debt obligations without relying solely on external financing. The margins reflect this complex financial picture, with a gross margin of 82.9% indicating high efficiency in production relative to costs, contrasted by an operating margin of -10.5% and a profit margin of -2.3% that show the pressure of overhead and non-operating items. On the balance sheet, the company holds $184.84M in cash against $198.78M in debt, resulting in a debt-to-equity ratio of 609.57, which characterizes a highly leveraged position typical for capital-intensive biopharmaceutical companies in growth phases. Liquidity is supported by a current ratio of 1.55, indicating that the company possesses 1.55 dollars in current assets for every dollar of current liabilities, providing a comfortable buffer for short-term obligations. Return on Equity is listed as N/A due to the negative equity base, while a Return on Assets of 5.4% demonstrates that management is generating positive returns on the total asset base despite the overall net loss position.

Valuation Assessment

Valuation metrics for Akebia Therapeutics show a trailing P/E Ratio (TTM) of N/A and a forward P/E of -14.63, implying that the market is pricing in future earnings recovery rather than current profitability. The price-to-book ratio stands at 11.30, which indicates a significant market premium over the company's book value, a common valuation characteristic for biotech firms where investors price in the potential value of their intellectual property and future drug approvals. Alternative valuation measures such as a price-to-sales ratio of 1.58 and an EV/EBITDA of 14.16 provide context for the stock's price relative to its revenue generation and operational earnings power. The stock has traded between a 52-week high of $4.08 and a 52-week low of $1.14, and depending on the current market price, the stock is trading at a specific percentage distance from these historical bounds, reflecting the volatility inherent in biotechnology equities. The beta of 0.40 suggests that the stock price is less volatile than the broader market, moving with only 40% of the intensity of the overall market index during periods of fluctuation.

Growth & Income

Revenue growth for the trailing twelve months is recorded at 23.9%, while earnings growth is N/A, indicating that top-line expansion is currently outpacing any potential bottom-line improvement due to the ongoing net losses. Since the company does not pay a dividend, the dividend yield is N/A and the payout ratio is 0.0%, meaning the company reinvests all available earnings and cash flow back into growth initiatives like clinical trials and product expansion rather than distributing income to shareholders. The overall growth and income profile is defined by strong revenue expansion supported by robust free cash flow generation, even in the absence of current profitability or dividend distributions. This reinvestment strategy is standard for companies in the drug manufacturing sector that prioritize product pipeline advancement over immediate shareholder returns.

Peer Comparison

Akebia Therapeutics, Inc. (AKBA) operates in the Drug Manufacturers - Specialty & Generic industry. Here is how it compares to its closest peers by market capitalization:

Company Ticker Market Cap P/E Ratio
Akebia Therapeutics, Inc. AKBA $278.99M N/A
Takeda Pharmaceutical Company Limited TAK $50.14B 41.8
Haleon plc HLN $40.92B 18.5
Teva Pharmaceutical Industries Limited TEVA $40.30B 25.8

The Drug Manufacturers - Specialty & Generic industry average P/E ratio is 47.5x. Akebia Therapeutics, Inc. trades at a P/E of N/A.

This analysis is AI-generated for informational purposes only and should not be considered financial advice. Data may be delayed or inaccurate. Always do your own research and consult a qualified financial advisor before making investment decisions.

About Akebia Therapeutics, Inc.

Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. Its product portfolio includes Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent (DD) and non-dialysis dependent (NDD) patients; and Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD and the treatment of iron deficiency anemia in adult patients with NDD-CKD. The company is also developing AKB-9090, which is in Phase 2 clinical trial for treating cardiac surgery-related acute kidney injury and acute respiratory distress syndrome; and AKB-10108 for the treatment of retinopathy of prematurity in neonates. The company has license and collaboration agreements with Tanabe Pharma Corporation for the development and commercialization of Vafseo in Japan and other Asian countries; Vafseo License and Collaboration Agreements; CSL Vifor Agreements; Averoa License Agreement; License Agreement with Panion & BF Biotech, Inc.; Cyclerion Therapeutics License Agreement; and Q32 Asset Purchase Agreement. Akebia Therapeutics, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

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Key Statistics

Market Cap
$278.99M
P/E Ratio
N/A
52-Week High
$4.08
52-Week Low
$0.88
Avg Volume
3.55M
Beta
0.35

Data provided by Yahoo Finance via yfinance. Updated daily.

Company Info

Exchange
NASDAQ
Country
United States
Employees
194