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Septerna, Inc. (SEPN) Análise de ações

Saúde

Septerna, Inc.

$30.64

+$2.29 (+8.06%)

Última atualização: 26 de maio de 2026

Histórico de Preços

Análise

Visão geral da empresa

A clinical-stage biotechnology firm, Septerna, Inc. is dedicated to the discovery and development of oral small molecule products targeting G protein-coupled receptors (GPCR) for applications in endocrinology, immunology, inflammation, and metabolic diseases. The company operates within the healthcare sector, specifically the biotechnology industry, which typically involves high capital expenditure and a long development timeline before commercialization of new therapies. Septerna maintains a market capitalization of $1.10B and reports an annual revenue (TTM) of $45.95M, employing a workforce of 130 individuals. These valuation and revenue figures suggest that the market assigns significant potential value to the company's pipeline, particularly its PTH1R Program involving oral small molecule Parathyroid Hormone 1, despite the current lack of profitability. The disparity between the substantial market cap and the relatively modest revenue stream is characteristic of early-stage biotechnology companies where investor pricing is heavily weighted toward future clinical success rather than current cash flows.

Saúde financeira

The company reported revenue of $45.95M over the trailing twelve months, while recording a net income of -$48,879,000 and an EBITDA of -$79,193,000. The significant gap between the positive revenue and the deeply negative net income reveals a cost structure dominated by high research and development expenses typical of clinical-stage operations. Despite the operating losses, the company generated positive free cash flow of $18.81M, which provides essential financial flexibility to fund ongoing clinical trials without immediate reliance on external equity financing. The gross margin stands at 100.0%, indicating that the cost of goods sold is negligible relative to sales, while the operating margin of -66.4% and profit margin of -106.4% reflect the intense investment required to bring a drug to market. Septerna holds a cash balance of $391.09M against total debt of $23.62M, resulting in a debt-to-equity ratio of 6.19, which suggests a balance sheet that is highly leveraged in terms of equity but possesses ample liquid assets to cover obligations. The current ratio of 4.73 indicates strong short-term liquidity, as the company's current assets are more than four times its current liabilities. Furthermore, the return on equity is -12.2% and the return on assets is -9.6%, metrics that reveal that management is currently utilizing shareholder capital to generate losses as part of the growth strategy rather than immediate profit generation.

Avaliação de valorização

The valuation metrics show a trailing P/E ratio of N/A due to negative earnings, while the forward P/E is listed as -12.59, implying that the market expects earnings to remain negative or volatile in the near term. The price-to-book ratio is 2.87, which indicates that the stock is trading at a premium of nearly three times its net asset value, a common phenomenon for companies with valuable intangible assets like intellectual property. Alternative valuation metrics such as the price-to-sales ratio of 23.93 and an EV/EBITDA of -9.25 suggest that investors are pricing the company based on future revenue potential rather than current profitability or earnings power. Regarding price volatility, the 52-week high is $32.63 and the 52-week low is $4.66, meaning the current price sits significantly below the 52-week high and near the lower end of its trading range over the past year. The beta value is N/A, which implies that historical volatility data relative to the broader market index is either unavailable or not calculated for this specific stock, limiting the ability to quantify systematic risk using standard metrics.

Growth & Income

Revenue growth year-over-year has surged by 11276.4%, reflecting a massive expansion in sales, possibly driven by the commercial launch of specific products or strategic acquisitions, whereas earnings growth is N/A due to the absence of positive net income. The company does not pay dividends, evidenced by a dividend yield of N/A and a payout ratio of 0.0%, which means all available earnings are theoretically reinvested into research and development rather than distributed to shareholders. Since the company is not a dividend payer, the strategy focuses entirely on capital appreciation and pipeline expansion to create long-term value. The overall growth and income profile for Septerna is characterized by explosive revenue expansion and a complete reliance on capital markets for funding operations, offering no current income yield to investors.

Comparação com pares

Septerna, Inc. (SEPN) atua no setor de Biotecnologia. Veja como se compara com seus pares mais próximos por capitalização de mercado:

Empresa Ticker Cap. de Mercado Índice P/L
Septerna, Inc. SEPN $1.38B N/A
Vertex Pharmaceuticals Incorporated VRTX $110.64B 25.8
Regeneron Pharmaceuticals, Inc. REGN $66.98B 15.6
argenx SE ARGX $50.52B 36.0

O índice P/L médio do setor Biotecnologia é 53.8x. Septerna, Inc. é negociada a um P/L de N/A.

Esta análise é gerada por IA apenas para fins informativos e não constitui aconselhamento financeiro. Os dados podem estar atrasados ou imprecisos. Sempre faça sua própria pesquisa e consulte um consultor financeiro qualificado antes de tomar decisões de investimento.

Sobre Septerna, Inc.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves' disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women's health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

A descrição da empresa é mostrada em inglês.

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Estatísticas Principais

Capitalização
$1.38B
Índice P/L
N/A
Máx. 52 Sem.
$32.63
Mín. 52 Sem.
$9.11
Volume Médio
318.48K

Dados fornecidos pelo Yahoo Finance via yfinance. Atualizado diariamente.

Informações da Empresa

Indústria
Biotecnologia
Bolsa
NASDAQ
País
United States
Funcionários
130